21 research outputs found
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
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- The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
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- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
A Comparative Study of Task Scheduling and Load Balancing Techniques with MCT using ETC on Computational Grids
- Author
- Abraham A Buyya R, Nath B.
- Alam M Varshney AK.
- Braun TD Siegel HJ, Beck N, Bölöni LL, Maheswaran M, Reuther AI, Robertson JP, Theys MD, Yao B, Hensgen D, Freund RF.
- Chatrapati KS Rekha JU, Babu AV.
- Goswami S Das A.
- Grosan C Abraham A, Helvik B.
- Grzonka D Koƚodziej J, Tao J, Khan SU.
- Hao Y Liu G, Wen N.
- Keerthika P Kasthuri N.
- Kokilavani T Amalarethinam DG.
- Kokilavani T Amalarethinam DG.
- Kumar ES Sumathi A, Zubar HA.
- Lu K Zomaya AY.
- Patel DK Tripathy C.
- Rajavel R.
- Reddy KH Roy DS.
- Salimi R Motameni H, Omranpour H.
- Salimi R Motameni H, Omranpour H.
- Sathish K Reddy AR.
- Saxena R Kumar A, Kumar A, Saxena S.
- Selvi S Manimegalai D.
- Shah R Veeravalli B, Misra M.
- Shah SN Zakaria MN, Mahmood AK, Pal AJ, Haron N.
- Shahid M Raza Z, Sajid M.
- Shahid M Raza Z.
- Subrata R Zomaya AY, Landfeldt B.
- Wu M Sun XH.
- Xhafa F Barolli L.
- Xiao P Hu Z.
- Zarrabi A Samsudin K.
- Publication venue
- 'Indian Society for Education and Environment'
- Publication date
- Field of study
Developments in Hydrometallurgy
- Author
- A Fuwa
- A J Zeeuw Van der
- A Masana
- AB King
- AD Stuart
- AM Ellar
- AP Novikov
- AP Sychev
- AR Maycock
- B Pesic
- BF Smith
- C Musikas
- C Nunez
- C-T Huang
- D Bauer
- D Ellingson
- D Huahua
- D Pauly
- D Pouillon
- DB Dreisinger
- DI McKenzie
- DJ Fray
- DR Tyson
- DS Flett
- DW Kirk
- EA Aprahamian Jr.
- EF Aglietti
- EH Cho
- EH Cho
- EP Horwitz
- EP Horwitz
- F Barriga Mateos
- F J Alguacil
- F Letowski
- F Xun
- Fiona M. Doyle
- FJ Alguacil
- FK Crundwell
- FK Crundwell
- FK Crundwell
- FM Doyle
- G Bouboukas
- G Roy Chaudhury
- GA Jauregui
- GA Kordosky
- GJ McDougall
- GJ Parsons
- GK Chibuye
- GMK Abotsi
- GO Argall
- GP Demopoulos
- GW McDonald
- GW Warren
- H Majima
- H Majima
- H Michaelis von
- H Michaelis von
- H Oshmori
- H-Y Lee
- HG Vazarlis
- HJ Bart
- HK Lin
- I Brcic
- J Avraamides
- J Hala
- JA Eisele
- JB Farrow
- JB Hiskey
- JC Angus
- JD Miller
- JE Dutrizac
- JE Dutrizac
- JE Dutrizac
- JE Dutrizac
- JE Dutrizac
- JE Dutrizac
- JGH Preez du
- JH Bae
- JP Hicks
- JP Lotens
- JR Arnold
- JS Hopkins
- K Inoue
- K Inoue
- K Kondo
- K Mitsutomi
- K Sutill
- KC Nathsarma
- KE Haque
- KG Tan
- KG Tan
- KH Soldenhoff
- KH Soldenhoff
- KL Bhat
- KN Han
- KN Han
- KS Gratton
- KY Ki
- L Dukov
- L Ruixing
- L White
- L Zhou
- LG Leduc
- LL LakeZapata
- LL Tavlarides
- LN O’Quinn
- LP Berube
- M Abe
- M Akser
- M Grote
- M Kawahara
- M Tsezos
- MA Ford
- MC Fuerstenau
- MC Fuerstenau
- MC Fuerstenau
- MD Adams
- MD Adams
- ME Wadsworth
- ME Wadsworth
- MI Stefanakis
- MJ Dry
- MJ Zapatero
- MJV Beattie
- ML O’Malley
- MP Wardell
- NA Yakabu
- NC Hung
- NM Patel
- NN Clark
- NP Brandon
- NT Bailey
- NT Bailey
- O Kanome
- PVRB Sarma
- Q Rong
- R Chiarizia
- R Hirasawa
- R Kammel
- R Luo
- R Raudsepp
- R Woods
- RA Leonard
- RD Schmidt
- RG Holdich
- RJ Ragozzini
- RJM Wyllie
- RJM Wyllie
- RK Biswas
- RM Morrison
- RR Reddy
- S Acharya
- S Acharya
- S Addy
- S Chander
- S Colak
- S Mukkavilli
- S Raghavan
- S Stenstrom
- SB Kanungo
- SD Alexandratos
- SD Atchison
- SJ Al-Bazi
- SL Harris
- T Hirato
- T Hirato
- T Sato
- T Sato
- T Warnheim
- V Sanmugasunderam
- W Mulak
- W Mulak
- WA Rickelton
- WC Cooper
- WD Stanford
- WR Ernst
- Y Awakura
- Y Awakura
- Y Desin
- Y Konishi
- Y Paspaliaris
- Y Umetsu
- Y-C Hoh
- Z Wangsheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Alginate: Pharmaceutical and Medical Applications
- Author
- A Abdellatif
- A Angspatt
- A Dalaty Al
- A Gamboa
- A Hasan
- A Kumar
- A Kumar
- A Liberski
- A Nešić
- A Petchsomrit
- A Radhakrishnan
- A Rangaraj
- A Ruigh De
- A Sarker
- A Shilpa
- A Sosnik
- A Sumayya
- A Tøndervik
- A Wassermann
- AA Chang
- AA Egorov
- AD Augst
- AK Anal
- AL Hillberg
- AM Alsharabasy
- AR Liberski
- B Balakrishnan
- B Balakrishnan
- B Duan
- B Joddar
- B McSwain
- B Riva De la
- B Sibaja
- B Yao
- B-B Lee
- C García-Astrain
- C Godugu
- C Godugu
- C Knill
- CB Cunha da
- CH Goh
- CI Gama
- CJ Rogers
- CSC Chiew
- D Gregurec
- D Jaikumar
- D Jain
- D Kingsley
- D Maciel
- D Roy
- D Ummarino
- DF Duarte Campos
- DM Ramsey
- DS Seeli
- E Ausili
- E Caló
- E Chellini
- E Mata
- E Rosellini
- E Ruvinov
- E Thomas
- EA Kamoun
- EC Newsom
- EG Popa
- F Sarei
- G Coşkun
- G Duncan
- G Gainza
- G Kavoosi
- G Miralles
- G Orive
- G Orive
- G Simó
- G Skjåk-Bræk
- G Skjåk-Bræk
- G Yan
- GF Caetano
- GG d’Ayala
- GT Grant
- H Dai
- H Hajiali
- H Kaygusuz
- H Park
- H Ronghua
- H Xie
- H-J Kong
- H-R Lin
- HH Beherei
- HH Tønnesen
- HJ Kong
- HJ Kong
- HL Ma
- HS Samanta
- I Donati
- I Freeman
- I Liakos
- I Sweeney
- ID Hay
- J Cheng
- J Dahlmann
- J Guo
- J Koehler
- J Kopeček
- J Lewandowska-Łańcucka
- J Malakar
- J Shi
- J Sowjanya
- J Sun
- J Venkatesan
- J Yang
- J Yu
- J-B Lee
- J-S Yang
- JA Rowley
- JM Kanczler
- JM Unagolla
- JP Paques
- K Chen
- K Hölzl
- K Istenič
- K Murakami
- K Nahar
- K Paul
- K Sajesh
- K Wang
- KH Bouhadir
- KI Draget
- KI Draget
- KY Lee
- KY Lee
- L Agüero
- L Bagheri
- L Fan
- L George
- L Liu
- L Shao
- L Shapiro
- L Tarusha
- L Wang
- L Yu
- L Zhao
- M Amiri
- M Boissière
- M Esposito
- M Falkeborg
- M George
- M Hajská
- M Jakaria
- M Kessler
- M Martins
- M Mori
- M Ménard
- M Nieto-Suárez
- M Otterlei
- M Rezvanian
- M Rinaudo
- M Shachar
- M Summa
- M Szekalska
- M Szekalska
- M Szymonowicz
- M Tallawi
- M Tally
- M Yiğitoğlu
- MA LeRoux
- MA Moraes de
- MA Patel
- MC Straccia
- MFA Taleb
- MJ Cardoso
- MJ Costa
- MJ Franklin
- MJ Franklin
- MJ Franklin
- MP Hanga
- MØ Dalheim
- N Alemdar
- N Chamberlain
- N Chirani
- N Golafshan
- N Işıklan
- N Li
- N Reddy
- N Shaari
- N Wathoni
- N Yu
- NK Sachan
- O Catanzano
- O Gåserød
- O Jeon
- O Smidsrød
- O Smidsrød
- O Wichterle
- P Eiselt
- P Gabbai-Armelin
- P Gurikov
- P Li
- P Mukhopadhyay
- P Mukhopadhyay
- P Mukhopadhyay
- P Pankongadisak
- P Pasbakhsh
- P Vijayabaskar
- PM Arockianathan
- PS Gungor-Ozkerim
- PW Dettmar
- Q Wang
- R Al-Otoum
- R Awasthi
- R Fu
- R Gong
- R Zhou
- RG Schweiger
- RG Schweiger
- RJ Coleman
- RJ Linhardt
- RMSC Morais de
- RP Narayanan
- S Abdelghany
- S Alban
- S Bale
- S Benavides
- S Bubenikova
- S Carella
- S Chaluvadi
- S Chen
- S Choudhary
- S Das
- S Dhivya
- S Focaroli
- S Irving
- S Kumbhar
- S Mandal
- S Mazzitelli
- S Passemard
- S Quraishi
- S Rossi
- S Shah
- S Tam
- S Villani
- S Zhao
- S-C Chen
- S-F Lin
- S-J Shin
- SC-Y Lin
- SH Ching
- SJ Bidarra
- SJ Buwalda
- SK Williams
- SM Hosseini
- SN Pawar
- SO Park
- T Andersen
- T Anderson
- T Tripathy
- T Tripathy
- TA Davis
- TL Silva da
- UT Huynh
- V Tzankova
- W Shen
- W Wang
- W Xu
- WL Ng
- X Bai
- X Li
- X Liu
- X Meng
- X Xu
- X Yan
- X Zhang
- X Zhao
- X Zhao
- Y Qin
- Y Yan
- Y-H Lin
- Y-T Xue
- YS Zhang
- Z Naghizadeh
- Z Wang
- ZM Rashaan
- ZM Rzaev
- Ø Arlov
- Ý Mørch
- Ž Jovanović
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Due to their outstanding properties in terms of mild gelation conditions
and simple functionalization, biocompatibility, low toxicity, biodegradability,
non-antigenicity and chelating ability, as well as relatively low cost, alginates have
been widely used in a variety of biomedical applications including tissue engineering
and drug delivery systems. Smart alginate hydrogels for on-demand drug release in
response to environmental stimuli and 3D bioprinting will play an important role in
the future. These and the introduction of appropriate cell interactive features will be
crucial for many tissue engineering applications. The focus of the present chapter is
to highlight the great potential of the alginates as biomaterial for biomedical applications
and to discuss the role that alginate-based materials are likely to play in
biomedical applications in the future.info:eu-repo/semantics/publishedVersio
Benign Fibro-Osseous Lesions of the Craniofacial Complex A Review
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- A Daneshi
- A Daroszewska
- A Daroszewska
- A Johannsen
- A Punniamoorthy
- A Rojas-Villarraga
- A Russo
- A Sakamoto
- A Sakamoto
- A Stappen Van der
- AE Hughes
- AG Pfleiderer
- AS Miller
- B Bertrand
- B Buch
- B Chong
- BM Wenig
- BW Neville
- C Armstrong
- C Dunlap
- C Galgano
- CA Mitchell
- CA Mitchell
- CA Waldron
- CA Waldron
- CA Waldron
- CA Waldron
- CA Waldron
- CA Waldron
- CE Margo
- CE Margo
- CH Chen
- CJ Haven
- CJ Nortje
- CM Mooy
- CN Wang
- D Hosking
- D Oda
- DA Lannon
- DA McGowan
- DC Zimmerman
- DJ Summerlin
- DR Maxwell
- DS MacDonald-Jankowski
- DS MacDonald-Jankowski
- DT Millet
- E Belli
- E Lautenbach
- EC Orpe
- EK Goh
- EM Canger
- ES Siris
- EW Fisher
- F Alawi
- F Jattiot
- F Mahomed
- FJ Martinez-Tello
- G Gherardi
- G Rea
- GA Morgan
- GD Douglass
- GL Ellis
- GV Packota
- H Gogl
- H Mohammadi-Araghi
- HBG Robinson
- HC Rossbach
- HJ Mankin
- HJ Winer
- HL Jacobson
- HP Kessler
- I Velez
- I Waal Van Der
- IR Kramer
- J Bras
- J Hashimoto
- JA Hoyland
- JA Shields
- JB Ludlow
- JB Murphy
- JB O’Driscoll
- JE Hamner 3rd
- JH Yoon
- JR Cavey
- JR Sawyer
- JS Cannon
- K Antoniades
- K Ghadour
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- K Oikarinen
- KB Becktor
- KH Yip
- KR Phelps
- L Aggunlu
- L Faivre
- L Gennari
- L Harvey
- L Mancebo-Aragoneses
- L Michou
- L Sanctis de
- L Su
- L Su
- Lan Su
- LC Fonseca
- LC Hofbauer
- LC Johnson
- LC Schneider
- LR Eversole
- LR Eversole
- LR Eversole
- LR Eversole
- LS Weinstein
- LS Weinstein
- M Bhambhani
- M Campanacci
- M Fujikawa
- M Ganibegovic
- M Maki
- M Miyauchi
- M Salvati
- MA Birch
- MF Basle
- MF Basle
- MH Han
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- MJ Aldred
- MM Cohen Jr.
- MO al-Sebaei
- MP Whyte
- MP Whyte
- MP Whyte
- MT Gordon
- N Kalfa
- N Kurihara
- NJ Betts
- NJ Khoury
- P Dal Cin
- P Fransen
- P Fransen
- P Peris
- PA Edwards
- PE Horn Van Jr
- PF Perdigao
- PH Osterberg
- PJ Slootweg
- PJ Slootweg
- PJ Slootweg
- PJ Slootweg
- PJ Slootweg
- RA Abdelsayed
- RA Danforth
- RB Brannon
- RG Wallace
- RH Groot
- RJ Melrose
- RJ Reed
- Roy Eversole
- S El-Mofty
- S Eliasson
- S Goldberg
- S Jacobsson
- S Jacobsson
- S Lumbroso
- S Mintz
- S Storkel
- S Syrjanen
- S Toyosawa
- S Warnakulasuriya
- SA Lietman
- Samir ElMofty
- SH Thompson
- SJ Finical
- SK Young
- SR Singer
- ST Ong
- SV Reddy
- T Jafarov
- T Kawai
- T Kawai
- T Kawai
- TA Larheim
- TE Moore
- TP Williams
- V Tiziani
- VM Rao
- VS Lee
- W Jerjes
- WC Rabe
- WD Fraser
- WG Shafer
- WH Kelly
- XM Meng
- Y Ariji
- Y Higuchi
- Y Imai
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- Y Ramon
- Y Sagliker
- Y Suei
- YS Cheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Low temperature selective catalytic reduction of NO<sub>x</sub> with NH<sub>3</sub> over Mn-based catalyst: A review
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- Thirupathi B Smirniotis PG
- Tuenter G Vanleeuwen WF, Snepvangers LJM
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- 'American Institute of Mathematical Sciences (AIMS)'
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- 01/01/2016
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The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention
- Author
- A Abdollahi
- A Aoyama
- A Elnemr
- A Grey
- A Itami
- A Mantovani
- A Pozzi
- A Rubenstrunk
- A Tenenbaum
- AD Burdick
- AD Burdick
- AM Lefebvre
- AV Schwartz
- AV Schwartz
- B Davidson
- B Delage
- B Farrow
- B Zhu
- BD Abbott
- BG Shearer
- BG Shearer
- BH Park
- BJ Tong
- C Cheung
- C Grommes
- C Piccinni
- C Qin
- C Rohrl
- C Sharma
- C Wang
- CA McAlpine
- CB Pollock
- CK Glass
- CK Osborne
- CW Shiau
- CY Hao
- D Bishop-Bailey
- D Panigrahy
- D Wang
- D Wang
- DA Notterman
- DJ Kim
- DJ Kim
- DJ Kim
- DL Crowe
- DL Sprecher
- DS Straus
- E Erdmann
- E Kebebew
- E Mueller
- E Saez
- E Saez
- EC Jaeckel
- EE Girroir
- F Balkwill
- F Biscetti
- F Chen
- F Chen
- F Yin
- FL Khanim
- FR Greten
- Frank J. Gonzalez
- FS Harman
- G Debrock
- G Pascual
- GA Orner
- GD Demetri
- GD Girnun
- GK Schwartz
- H Fu
- H Koga
- H Koga
- H Kohno
- H Lapillonne
- H Takahashi
- HE Hollingshead
- HE Hollingshead
- HE Marin
- HJ Burstein
- HJ Lim
- HK Knutsen
- HK Roy
- HP Koeffler
- I Issemann
- J Feilchenfeldt
- J Kasuga
- JD Burton
- JD Burton
- JE Foreman
- JE Foreman
- JE Foreman
- Jeffrey M. Peters
- Jeffrey M. Peters
- JH Choi
- JI Hisatake
- JK Reddy
- JM Peters
- JM Peters
- JM Peters
- JM Peters
- JM Peters
- JM Peters
- JW Huang
- K Brautigam
- K Chu
- K Matsusue
- K Morimura
- K Schultze
- K Still
- K Tachibana
- K Tikoo
- K Yamazaki
- K Yang
- KH Yan
- KL Schaefer
- KM Sheehan
- KR Reed
- KS Kilgore
- KY Kim
- KY Wolin
- L Fajas
- L Jackson
- L Lacroix
- L Patel
- L Piqueras
- L Szeles
- L Yang
- L Yang
- LC Chen
- M Adachi
- M Guerre-Millo
- M Meissner
- M Schupp
- M Uhlen
- M Yoshinaga
- M Yoshinaga
- MA Bae
- MA Lea
- MA Peraza
- MD Leibowitz
- MG Borland
- MG Borland
- MH Fenner
- MH Kulke
- MR Smith
- MT Bility
- MT Bility
- MV Pino
- N Ahmed
- N Di-Poi
- N Hamaguchi
- N Niho
- N Ouyang
- NS Tan
- NT Zaveri
- O Takayama
- OJ Sansom
- P Desreumaux
- P Escher
- P Hau
- P Sarraf
- P Tontonoz
- P Tontonoz
- P Tontonoz
- PH Huang
- PS Palkar
- Q Zhang
- R Yoshimura
- RA Gupta
- RA Gupta
- RA Gupta
- RA Lubet
- RC Reddy
- RE Hayden
- RE Teresi
- RI Glazer
- RK Semple
- RL Stephen
- RM Cesario
- S Drori
- S Fauconnet
- S Kersten
- S Liu
- S Mandard
- S Modica
- S Müller-Brüsselbach
- S Naruhn
- S Ogino
- S Tepmongkol
- S Tsugane
- S Wei
- S Wei
- SE Kahn
- SR Pyper
- SS Palakurthi
- SY Lee
- T Adhikary
- T Baetz
- T Fevr
- T Hays
- T Nagasawa
- T Nijsten
- T Tanaka
- T Tanaka
- T Varga
- T Yoshizumi
- T Zander
- TC He
- TG Kroll
- TJ Giordano
- TT Schug
- V Chintalgattu
- VA Narkar
- W Motomura
- W Shan
- W Shan
- W Zhang
- WH Koppenol
- WL Read
- WR Oliver Jr.
- X Xin
- X Zuo
- Y Barak
- Y Kim
- Y Kodera
- Y Li
- Y Shi
- Y Yokoyama
- Y Zhu
- Yatrik M. Shah
- YM Shah
- YM Shah
- YX Wang
- YX Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Global Retinoblastoma Presentation and Analysis by National Income Level.
- Author
- Abdallah E
- Abdullahi SU
- Abdulqader RA
- Adamou Boubacar S
- Ademola-Popoola DS
- Adio A
- Afshar AR
- Aggarwal P
- Aghaji AE
- Ahmad A
- Akib MNR
- Al Ani MH
- Al Harby L
- Al-Badri SAF
- Al-Dahmash SA
- Al-Haddad C
- Al-Hussaini HHY
- Al-Jadiry MF
- Al-Jumaly U
- Al-Mafrachi AARM
- Al-Shaheen AASM
- Al-Shammary EH
- Alakbarova A
- Alcasabas APA
- Alejos A
- Alemany-Rubio E
- Alfa Bio AI
- Alfonso Carreras Y
- Ali AM
- Alia DB
- Alkatan HM
- All-Eriksson C
- Almeida AA
- Alsawidi KM
- Amiruddin PO
- Antonino R
- Astbury NJ
- Atalay HT
- Atchaneeyasakul L-O
- Atsiaya R
- Attaseth T
- Aung TH
- Ayala S
- Baizakova B
- Balaguer J
- Balayeva R
- Balwierz W
- Barranco H
- Bascaran C
- Beck Popovic M
- Benavides R
- Benmiloud S
- Bennani Guebessi N
- Berete RC
- Berry JL
- Bhaduri A
- Bhat S
- Biddulph SJ
- Biewald EM
- Bobrova N
- Boehme M
- Boldt HC
- Bonanomi MTBC
- Bornfeld N
- Bouda GC
- Bouguila H
- Boumedane A
- Bowman R
- Brennan RC
- Brichard BG
- Buaboonnam J
- Calderón-Sotelo P
- Calle Jara DA
- Camuglia JE
- Cano MR
- Capra M
- Cassoux N
- Castela G
- Castillo L
- Català-Mora J
- Chantada GL
- Chaudhry S
- Chaugule SS
- Chauhan A
- Chawla B
- Chernodrinska VS
- Chiwanga FS
- Chuluunbat T
- Cieslik K
- Cockcroft RL
- Comsa C
- Correa Llano MG
- Correa ZM
- Corson TW
- Cowan-Lyn KE
- Csóka M
- Cui X
- Da Gama IV
- Dangboon W
- Das A
- Das S
- Davanzo JM
- Davidson A
- De Potter P
- Delgado KQ
- Demirci H
- Desjardins L
- Diaz Coronado RY
- Dimaras H
- Dodgshun AJ
- Donaldson C
- Donato Macedo CR
- Dragomir MD
- Du Bruyn M
- Du Y
- Edison KS
- Eka Sutyawan IW
- El Kettani A
- Elbahi AM
- Elder JE
- Elgalaly D
- Elhaddad AM
- Elhassan MMA
- Elzembely MM
- Essuman VA
- Evina TGA
- Fabian ID
- Fadoo Z
- Fandiño AC
- Faranoush M
- Fasina O
- Fernández DDPG
- Fernández-Teijeiro A
- Foster A
- Frenkel S
- Fu LD
- Fuentes-Alabi SL
- Gallie BL
- Gandiwa M
- Garcia Pacheco HN
- Garcia JL
- García Aldana D
- Gassant PY
- Geel JA
- Ghassemi F
- Girón AV
- Gizachew Z
- Global Retinoblastoma Study Group
- Goenz MA
- Gold AS
- Goldberg-Lavid M
- Gole GA
- Gomel N
- Gonzalez Perez G
- Gonzalez E
- González-Rodríguez L
- Graells J
- Green L
- Gregersen PA
- Grigorovski NDAK
- Guedenon KM
- Gunasekera DS
- Gupta H
- Gupta S
- Gündüz AK
- Hadjistilianou T
- Hamel P
- Hamid SA
- Hamzah N
- Hansen ED
- Harbour JW
- Hartnett ME
- Hasanreisoglu M
- Hassan S
- Hassan S
- Hederova S
- Hernandez J
- Hernandez LMC
- Hessissen L
- Hordofa DF
- Huang LC
- Hubbard GB
- Hummlen M
- Husakova K
- Hussein Al-Janabi AN
- Ida R
- Ilic VR
- Jairaj V
- Jeeva I
- Jenkinson H
- Ji X
- Jo DH
- Johnson KP
- Johnson WJ
- Jones MM
- Kabesha TBA
- Kabore RL
- Kaliki S
- Kalinaki A
- Kantar M
- Kao L-Y
- Kardava T
- Kebudi R
- Kepak T
- Keren-Froim N
- Khan ZJ
- Khaqan HA
- Khauv P
- Kheir WJ
- Khetan V
- Khodabande A
- Khotenashvili Z
- Kim JH
- Kim JW
- Kiratli H
- Kivelä TT
- Klett A
- Komba Palet JEK
- Krivaitiene D
- Kruger M
- Kulvichit K
- Kuntorini MW
- Kyara A
- Lachmann ES
- Lam CPS
- Lam GC
- Larson SA
- Latinovic S
- Laurenti KD
- Le BHA
- Lecuona K
- Leverant AA
- Li C
- Limbu B
- Long QB
- Lukamba RM
- Lumbroso L
- Luna-Fineman S
- Lutfi D
- Lysytsia L
- López JP
- Magrath GN
- Mahajan A
- Majeed AR
- Maka E
- Makan M
- Makimbetov EK
- Manda C
- Martín Begue N
- Mason JO
- Mason L
- Matende IO
- Materin M
- Mattosinho CCDS
- Matua M
- Mayet I
- Mbumba FB
- McKenzie JD
- Medina-Sanson A
- Mehrvar A
- Mengesha AA
- Menon V
- Mercado GJVD
- Mets MB
- Midena E
- Mishra DKC
- Mndeme FG
- Mohamedani AA
- Mohammad MT
- Moll AC
- Montero MM
- Morales RA
- Moreira C
- Mruthyunjaya P
- Msina MS
- Msukwa G
- Mudaliar SS
- Muma KI
- Munier FL
- Murgoi G
- Murray TG
- Musa KO
- Mushtaq A
- Mustak H
- Muyen OM
- Naidu G
- Nair AG
- Naumenko L
- Ndoye Roth PA
- Nency YM
- Neroev V
- Ngo H
- Nieves RM
- Nikitovic M
- Nkanga ED
- Nkumbe H
- Nuruddin M
- Nyaywa M
- Obono-Obiang G
- Oguego NC
- Olechowski A
- Oliver SCN
- Osei-Bonsu P
- Ossandon D
- Paez-Escamilla MA
- Pagarra H
- Painter SL
- Paintsil V
- Paiva L
- Pal BP
- Palanivelu MS
- Papyan R
- Parrozzani R
- Parulekar M
- Pascual Morales CR
- Paton KE
- Pawinska-Wasikowska K
- Pe'er J
- Peric S
- Peña A
- Pham CTM
- Philbert R
- Plager DA
- Pochop P
- Polania RA
- Polyakov VG
- Pompe MT
- Pons JJ
- Portabella SA
- Prat D
- Prom V
- Purwanto I
- Qadir AO
- Qayyum S
- Qian J
- Rahman A
- Rahman S
- Rahmat J
- Rajkarnikar P
- Ramanjulu R
- Ramasubramanian A
- Ramirez-Ortiz MA
- Raobela L
- Rashid R
- Reddy MA
- Reich E
- Renner LA
- Reynders D
- Ribadu D
- Riheia MM
- Ritter-Sovinz P
- Rojanaporn D
- Romero L
- Roy SR
- Saab RH
- Saakyan S
- Sabhan AH
- Sagoo MS
- Said AMA
- Saiju R
- Salas B
- San Román Pacheco S
- Sayalith P
- Scanlan TA
- Schefler AC
- Schoeman J
- Sedaghat A
- Seregard S
- Seth R
- Shah AS
- Shakoor SA
- Sharma MK
- Sherief ST
- Shetye NG
- Shields CL
- Siddiqui SN
- Sidi Cheikh S
- Silva S
- Singh AD
- Singh N
- Singh U
- Singha P
- Sitorus RS
- Skalet AH
- Soebagjo HD
- Sorochynska T
- Ssali G
- Stacey AW
- Staffieri SE
- Stahl ED
- Stathopoulos C
- Stirn Kranjc B
- Stones DK
- Strahlendorf C
- Suarez MEC
- Sultana S
- Sun X
- Sundy M
- Superstein R
- Supriyadi E
- Surukrattanaskul S
- Suzuki S
- Svojgr K
- Sylla F
- Sánchez GL
- Tamamyan G
- Tan D
- Tandili A
- Tarrillo Leiva FF
- Tashvighi M
- Tateshi B
- Teh KH
- Tehuteru ES
- Teixeira LF
- Theophile T
- Toledano H
- Trang DL
- Traoré F
- Trichaiyaporn S
- Tuncer S
- Tyau-Tyau H
- Umar AB
- Unal E
- Uner OE
- Urbak SF
- Ushakova TL
- Usmanov RH
- Valeina S
- van Hoefen Wijsard M
- Varadisai A
- Vasquez L
- Vaughan LO
- Veleva-Krasteva NV
- Verma N
- Victor AA
- Viksnins M
- Villacís Chafla EG
- Vishnevskia-Dai V
- Vora T
- Wachtel AE
- Wackernagel W
- Waddell K
- Wade PD
- Wali AH
- Wang Y-Z
- Weiss A
- Wilson MW
- Wime ADC
- Wiwatwongwana A
- Wiwatwongwana D
- Wolley Dod C
- Wongwai P
- Xiang D
- Xiao Y
- Yam JC
- Yang H
- Yanga JM
- Yaqub MA
- Yarovaya VA
- Yarovoy AA
- Ye H
- Yousef YA
- Yuliawati P
- Zapata López AM
- Zein E
- Zhang C
- Zhang Y
- Zhao J
- Zheng X
- Zhilyaeva K
- Zia N
- Ziko OAO
- Zondervan M
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 27/02/2020
- Field of study
Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale.
To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis.
A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017.
Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis.
The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]).
This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs
Reactive oxygen species in cancer
- Author
- Ahmad IM
- Ahmed KM
- Alexandre J
- Algul H
- Antosiewicz J
- Arner ES
- Aunoble B
- Aykin-Burns N
- Babior BM
- Babior BM
- Bae YS
- Balkwill F
- Bao S
- Basseres DS
- Beg AA
- Beg AA
- Behrend L
- Ben Mahdi MH
- Bendayan M
- Bergmann M
- Bertout JA
- Beutler E
- Bienert GP
- Biswas DK
- Biswas DK
- Bonekamp NA
- Bonizzi G
- Bourguignon LY
- Brenneisen P
- Brigelius-Flohe R
- Broom OJ
- Brown LF
- Brown NS
- Browne SE
- Brunet A
- Burdick AD
- Burdon RH
- Burhans WC
- Cadenas E
- Carew JS
- Carlberg I
- Chan DW
- Chen CY
- Cheng GC
- Chiarugi P
- Chiu TT
- Chung YM
- Claffey KP
- Claudio E
- Colavitti R
- Coleman MC
- Copin JC
- Cowell CF
- Crompton M
- Cui S
- Cullen JJ
- Dang CV
- Dansen TB
- Dayal D
- del Rio LA
- Delhase M
- Dewhirst MW
- Diaz B
- Diehn M
- Donadelli M
- Doppler H
- Duffey DC
- Eiseler T
- Erler JT
- Felty Q
- Felty Q
- Felty Q
- Ferraro D
- Franco R
- Gahr S
- Ganapathy V
- Gardner HW
- Geou-Yarh Liou
- Ghoda L
- Gianni D
- Giannoni E
- Gottlieb E
- Goustin AS
- Govindarajan B
- Greer JB
- Griendling KK
- Gupta A
- Hacker H
- Han D
- Harris AL
- Hashimoto F
- Hayes JD
- Higaki Y
- Hitchler M. J
- Hockel M
- Hofmann B
- Holmgren A
- Hsu PP
- Huo YY
- Imbert V
- Imlay JA
- Irani K
- Irani K
- Janssen-Heininger YM
- Kaelin WG
- Karin M
- Kheradmand F
- Kim JS
- Kundu N
- Kuo PL
- Lander HM
- Lauschke H
- Lee CH
- Lee KH
- Lee SR
- Lee WK
- Levine RL
- Lewis A
- Li N
- Li Q
- Ling L
- Litwin JA
- Liu LZ
- Llobet D
- Lo YY
- Lowenfels AB
- Ma J
- Manna SK
- Marchetti M
- Maynard S
- Mazzio EA
- McCubrey JA
- McLachlan A
- McLean L
- Menon SG
- Mihailovic T
- Milligan SA
- Minamoto T
- Minamoto T
- Mitra S
- Mochizuki T
- Moldovan L
- Mukhopadhyay A
- Murakami M
- Mustacich D
- Nelson AR
- Nelson KK
- Neumann CA
- North JA
- Ogg S
- Ohba M
- Osada S
- Pani G
- Park SA
- Parkash J
- Pastorino JG
- Pelicano H
- Peter Storz
- Pouyssegur J
- Prasad N
- Qanungo S
- Qi XJ
- Rabbani ZN
- Radisky DC
- Rajagopalan S
- Rayet B
- Reddy KB
- Reichenbach J
- Rhee SG
- Roberts PJ
- Roebuck KA
- Rofstad EK
- Roy D
- Ruiz-Ramos R
- Rygiel TP
- Sahu RP
- Saitoh M
- Sandhya T
- Sarsour EH
- Schulze-Osthoff K
- Senger DR
- Shackleton M
- Shankar S
- Shankar S
- Sharma R
- Shi Y
- Shim H
- Shin EA
- Simon HU
- Singh I
- Singh S
- Song J
- Spitz DR
- Squier TC
- Srivastava SK
- Steelman LS
- Storz P
- Storz P
- Storz P
- Storz P
- Storz P
- Storz P
- Storz P
- Storz P
- Sun H
- Sundaresan M
- Svineng G
- Szatrowski TP
- Takeda K
- Tiku ML
- Tobar N
- Tothova Z
- Townsend DM
- Trachootham D
- Ursini F
- van Wetering S
- Visvader JE
- Wang M
- Wang Y
- Ward JF
- Wartenberg M
- Wells-Knecht MC
- Wenk J
- Werner E
- Westermarck J
- Wood ZA
- Wouters BG
- Wu WS
- Xia C
- Xiao H
- Xin M
- Xu YC
- You H
- Zhang R
- Zhang W
- Zhang Y
- Zhou J
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Applications of Nanobiomaterials in the Therapy and Imaging of Acute Liver Failure
- Author
- A Banas
- A Bielinska
- A El-Sayed
- A Higuchi
- A Higuchi
- A Higuchi
- A Lamprecht
- A Napoli
- A Pietrzak-Nguyen
- A Tagami
- AB Fajardo-Puerta
- AR Ahmadi
- B Huang
- B Kim
- B Oh
- B Smedsrød
- BL Lin
- BL Woolbright
- C Akao
- C Bernsmeier
- C Ergen
- C Kang
- C Nathan
- C Rose
- C Tapeinos
- C-K Chen
- CE Nelson
- CF Jones
- CG Antoniades
- CG Antoniades
- CN Jenne
- CW Lee
- CX Lin
- CY Tan
- D Dal-Secco
- D Lee
- D Shi
- D Yoo
- DK Yi
- DM Mosser
- DS Zagoura
- E Ko
- E Triantafyllou
- EL Romero
- F Filipponi
- F Heymann
- F Hoffmann
- F Suriano
- FJ Cubero
- FL Yen
- FQ Fan
- G Chen
- G Li Volti
- G Tiegs
- G-W Kim
- G-Z Jin
- GC Chen
- H He
- H Joyeux
- H Kim
- H Liang
- H Makino
- H Park
- H Tsutsui
- H Volt
- H Yukawa
- HC Cho
- HF Liang
- HH Wu
- HJ Heo
- HL Wang
- HX Wang
- I Aurich
- I Batinic-Haberle
- I Batinic-Haberle
- I Ogushi
- IC Sun
- J Ding
- J Fan
- J Kolosnjaj-Tabi
- J Kurreck
- J Nam
- J Pihlajamaki
- J Puppi
- J Wang
- J Wendon
- J Wu
- J-W Kang
- JA Dudakov
- JN Tiwari
- JQ Xiao
- JS Kang
- JU Baenziger
- JW Bulte
- K Knubben
- K Nakazawa
- K Poelstra
- K Sheth
- K Tonnesen
- K Tonnesen
- K Xiao
- K Yanagisawa
- KA Whitehead
- KD Lee
- KH Min
- KL Kozielski
- KM Kamruzzaman Selim
- KM Nelson
- KP Patel
- KR Karlmark
- L Brannon-Peppas
- L Chen
- L Feng
- L Kong
- L Li
- LA Zenewicz
- LB Jeng
- LE Schmidt
- LH Reddy
- LL Estevanato
- LM Ytrebø
- LM Ytrebø
- LP Liang
- M Baker
- M Bélanger
- M Hu
- M Levy
- M Li
- M Lotfinia
- M Maes
- M Otsuka
- M Schuldiner
- M Yoshida
- MA Dobrovolskaia
- MC Londono
- ME Davis
- MJ Tuñón
- MM Berger
- MN Sosef
- MR Ali
- MR McGill
- MR McGill
- MRA Abdollah
- MS Shim
- MX Xu
- MY Wang
- N Davoodian
- N Jiang
- N Mishra
- N Rolando
- NP Trivedi
- NS Hwang
- O Cheung
- OF Khan
- P Boonruamkaew
- P Kubes
- P Opanasopit
- P Roy
- P Shukla
- PCN Rensen
- PH Weigel
- R Cheng
- R Doddapaneni
- R Haas
- R Hickman
- R Kubota
- R Martin-Mateos
- R Medzhitov
- R Morishita
- R Morishita
- R Silverstein
- RA Petros
- RK Singh
- S An
- S Diez
- S Eguchi
- S Feng
- S Fujisawa
- S Girard
- S Liang
- S Sen
- S Shen
- S Snykers
- S Son
- S Wang
- S Wei
- S Wilhelm
- S Wilhelm
- S-H Cheng
- SC Shen
- SC Yang
- SD Khaja
- SK Balasubramanian
- SK Libutti
- SL Wang
- SM Moghimi
- SM Opal
- SV BerwinSingh
- T Hanawa
- T Hirano
- T Nakamura
- T Terada
- T Zhang
- TE Fick
- TK Jain
- V Dubey
- V Moenkemoeller
- VC Cogger
- W Bernal
- W Chen
- W Khamri
- W Poon
- W Zhang
- WI Weis
- WR Jo
- X Lin
- X Yang
- XG Deng
- XR Qi
- Y Cao
- Y Chien
- Y Dong
- Y Gao
- Y Go
- Y He
- Y Higuchi
- Y Higuchi
- Y Jiang
- Y Li
- Y Liu
- Y Liu
- Y Liu
- Y Zhang
- YC Li
- YH Wang
- YJ Kwon
- YJ Xu
- YL Colson
- YN Zhang
- YN Zhang
- YX Wang
- YX Wang
- Z Chen
- Z Liu
- Z Liu
- Z Machaidze
- Z Wang
- Z Zhang
- Z Zhou
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study