The timber footprint of the German bioeconomy - state of the art and past development

Gefördert durch den Publikationsfonds der Universität Kasse

The Timber Footprint of the German Bioeconomy—State of the Art and Past Development

The article gives a comprehensive overview of the roundwood equivalents (RE) consumed in the German bioeconomy from Germany and abroad between 1995 and 2015, i.e., the Timber Footprint of final Consumption (TFPcon). The calculation is based on an adapted version of Exiobase 3.4. The sustainability of roundwood procurement for the TFPcon is assessed. A systematic embedding of the tree compartments considered in the TFP in the context of national forest inventories and material flow analysis is presented. The results show that, in 2015, the total volume of the TFPcon of Germany is 90 Mm3 (slightly above the 1995 level) and is composed of 61% coniferous and 39% non-coniferous wood. Germany is strongly dependent on roundwood sourced from abroad and thus was a net importer of RE in 2015. Among the 17 countries with the largest supply of RE for the TFPcon, around one third very likely include large shares of roundwood procured from deforestation or clear-cutting. The self-sufficiency rate in 2015 was only 76%. It would be possible to increase domestic roundwood production by 8–41% (mainly in the hardwood sector) without exceeding the sustainability limits as defined in the WEHAM scenarios

Agricultural Development and Land Use Change in India: A Scenario Analysis of Trade‐Offs Between UN Sustainable Development Goals (SDGs)

Gefördert durch den Publikationsfonds der Universität Kasse

Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections.

Elimination of pulmonary Pseudomonas aeruginosa (PA) infections is challenging to accomplish with antibiotic therapies, mainly due to resistance mechanisms. Quorum sensing inhibitors (QSIs) interfering with biofilm formation can thus complement antibiotics. For simultaneous and improved delivery of both active agents to the infection sites, self-assembling nanoparticles of a newly synthesized squalenyl hydrogen sulfate (SqNPs) were prepared. These nanocarriers allowed for remarkably high loading capacities of hydrophilic antibiotic tobramycin (Tob) and a novel lipophilic QSI at 30 % and circa 10 %, respectively. The drug-loaded SqNPs showed improved biofilm penetration and enhanced efficacy in relevant biological barriers (mucin/human tracheal mucus, biofilm), leading to complete eradication of PA biofilms at circa 16-fold lower Tob concentration than Tob alone. This study offers a viable therapy optimization and invigorates the research and development of QSIs for clinical use