554 research outputs found

    A three dimensional model of the Venusian thermosphere with superrotation

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    An improved three dimensional spectral model of the thermosphere of Venus is described. The model solves the Navier-Stokes equations and includes nonlinear effects for an arbitrary number of atmospheric species. A two dimensional axisymmetric model of the superrotation of the thermosphere is also presented. This model addresses the Pioneer-Venus mission finding, which suggested the thermospheric rotation rate to be much higher than that of the planet as seen from the asymmetric distribution of hydrogen and helium. Both models include the effects of an anisotropic eddy diffusion that is consistent with atmospheric mixing length theory

    The Production of Propionic Acid from Pentoses by Propionibacterium pentosaceum

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    Propionibacterium pentosaceum attacks pentoses (xylose, arabinose) with the production of propionic and acetic acids

    Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies

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    The deciphering of the sequence of the human genome has raised the expectation of unravelling the specific role of each gene in physiology and pathology. High-throughput technologies for gene expression profiling provide the first practical basis for applying this information. In rheumatology, with its many diseases of unknown pathogenesis and puzzling inflammatory aspects, these advances appear to promise a significant advance towards the identification of leading mechanisms of pathology. Expression patterns reflect the complexity of the molecular processes and are expected to provide the molecular basis for specific diagnosis, therapeutic stratification, long-term monitoring and prognostic evaluation. Identification of the molecular networks will help in the discovery of appropriate drug targets, and permit focusing on the most effective and least toxic compounds. Current limitations in screening technologies, experimental strategies and bioinformatic interpretation will shortly be overcome by the rapid development in this field. However, gene expression profiling, by its nature, will not provide biochemical information on functional activities of proteins and might only in part reflect underlying genetic dysfunction. Genomic and proteomic technologies will therefore be complementary in their scientific and clinical application

    Special Publication No. 6, Subject: Nematoda and Nematode Diseases, Part 5: Supergenera, Genera, Species, and Subspecies: Sp-Z.

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    United States Department of Agriculture, Bureau of Animal Industr

    LPS from P. gingivalis

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    Objective. Oral inflammatory pathologies are linked to increased oxidative stress, thereby partly explaining their relevance in the etiology of systemic disorders. The purpose of this work was to determine the degree to which LPS from Porphyromonas gingivalis, the primary pathogen related to oral inflammation, altered gingival mitochondrial function and reactive oxygen species generation. Methods. Human gingival fibroblast (HGF-1) cells were treated with lipopolysaccharide of P. gingivalis. Mitochondrial function was determined via high-resolution respirometry. Results. LPS-treated HGF-1 cells had significantly higher mitochondrial complex IV and higher rates of mitochondrial respiration. However, this failed to translate into greater ATP production, as ATP production was paradoxically diminished with LPS treatment. Nevertheless, production of the reactive H2O2 was elevated with LPS treatment. Conclusions. LPS elicits an increase in gingival cell mitochondria content, with a subsequent increase in reactive oxygen species production (i.e., H2O2), despite a paradoxical reduction in ATP generation. These findings provide an insight into the nature of oxidative stress in oral inflammatory pathologies

    Supplement 19, Part 4, Parasite-Subject Catalogue: Parasites: Nematoda and Acanthocephala

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    United States Department of Agriculture, Bureau of Animal Industry, Animal Parasitology Institute, Agricultural Research Servic

    Supplement 24, Part 6, Parasite-Subject Catalogue, Treatment

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    United States Department of Agriculture, Bureau of Animal Industr

    Supplement 24, Part 1, Authors: A To Z

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    United States Department of Agriculture, Bureau of Animal Industr

    Supplement 21, Part 2, Parasite-Subject Catalogue, Parasites: Protozoa

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    United States Department of Agriculture, Bureau of Animal Industr
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