54 research outputs found
Extragalactic jets on subpc and large scales
Jets can be probed in their innermost regions (d~0.1 pc) through the study of
the relativistically-boosted emission of blazars. On the other extreme of
spatial scales, the study of structure and dynamics of extragalactic
relativistic jets received renewed impulse after the discovery, made by
Chandra, of bright X-ray emission from regions at distances larger than
hundreds of kpc from the central engine. At both scales it is thus possible to
infer some of the basic parameters of the flow (speed, density, magnetic field
intensity, power). After a brief review of the available observational
evidence, I discuss how the comparison between the physical quantities
independently derived at the two scales can be used to shed light on the global
dynamics of the jet, from the innermost regions to the hundreds of kpc scale.Comment: Proceedings of the 5th Stromlo Symposium: Disks, Winds, and Jets -
from Planets to Quasars. Accepted, to be published in Astrophysics & Space
Scienc
Comparative analysis of serine protease-related genes in the honey bee genome: possible involvement in embryonic development and innate immunity
We have identified 44 serine protease (SP) and 13 serine protease homolog (SPH) genes in the genome of Apis mellifera. Most of these genes encode putative secreted proteins, but four SPs and three SPHs may associate with the plasma membrane via a transmembrane region. Clip domains represent the most abundant non-catalytic structural units in these SP-like proteins â12 SPs and six SPHs contain at least one clip domain. Some of the family members contain other modules for proteinâprotein interactions, including disulphide-stabilized structures (LDL(r)A, SRCR, frizzled, kringle, Sushi, Wonton and Pan/apple), carbohydrate-recognition domains (C-type lectin and chitin-binding), and other modules (such as zinc finger, CUB, coiled coil and Sina). Comparison of the sequences with those from Drosophila led to a proposed SP pathway for establishing the dorsoventral axis of honey bee embryos. Multiple sequence alignments revealed evolutionary relationships of honey bee SPs and SPHs with those in Drosophila melanogaster, Anopheles gambiae, and Manduca sexta. We identified homologs of D. melanogaster persephone, M. sexta HP14, PAP-1 and SPH-1. A. mellifera genome includes at least five genes for potential SP inhibitors (serpin-1 through -5) and three genes of SP putative substrates (prophenoloxidase, spĂ€tzle-1 and spĂ€tzle-2). Quantitative RT-PCR analyses showed an elevation in the mRNA levels of SP2, SP3, SP9, SP10, SPH41, SPH42, SP49, serpin-2, serpin-4, serpin-5, and spĂ€tzle-2 in adults after a microbial challenge. The SP41 and SP6 transcripts significantly increased after an injection of Paenibacillus larva, but there was no such increase after injection of saline or Escherichia coli. mRNA levels of most SPs and serpins significantly increased by 48 h after the pathogen infection in 1st instar larvae. On the contrary, SP1, SP3, SP19 and serpin-5 transcript levels reduced. These results, taken together, provide a framework for designing experimental studies of the roles of SPs and related proteins in embryonic development and immune responses of A. mellifera
A lower bound on the local extragalactic magnetic field
Assuming that the hard gamma-ray emission of Cen A is a result of synchrotron
radiation of ultra-relativistic electrons, we derive a lower bound on the local
extragalactic magnetic field, G. This result is consistent with
(and close to) upper bounds on magnetic fields derived from consideration of
cosmic microwave background distortions and Faraday rotation measurements.Comment: Includes extensive discussion of particle acceleration above 10^20 eV
in the hot spot-like region of Cen
Production of silicon carbide Al 2124 alloy functionally graded materials by mechanical powder metallurgy technique
Modelling of MOSFET inversion layer conductivity using the resistor network method
8.00Available from British Library Document Supply Centre- DSC:9091.9F(AERE-M--3708) / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo
- âŠ