The Conselice Study of Brain Ageing

Among the age-related diseases, the development of cognitive impairments, in particular dementia, is the most devastating for the individual and has great social and healthcare costs. Accurate information is needed about the prevalence and incidence of cognitive disorders and the physiology of the ageing brain. In particular, only scant data are available about the relationship between ageing, cognitive status and nutritional factors. In order to address these issues we planned the Conselice Study of Brain Ageing, a longitudinal study of physiologic and pathologic brain ageing. The center involved in the study was the municipality of Conselice, Ravenna province, in the Northern Italian region Emilia-Romagna. A total of 1016 subjects aged 65 and over was enrolled at baseline. Information about cognitive status at 4-years of follow-up was collected for 940 of them. These data have been used to estimate prevalence and incidence of dementia in the elderly Italian population and to investigate the possible role of baseline blood homocysteine as risk factors for dementia

Coleta de material para diagnóstico das doenças infecciosas que interferem com a reprodução de bovinos.

O diagnóstico de problemas reprodutivos de bovinos é uma tarefa árdua e muitas das vezes sem o resultado esperado, em função do grande número de fatores ambientais, de manejo, nutricionais e infeciosos envolvidos. A avaliação dos parâmetros nutricionais, ambientais e de manejo são muito importantes para se diferenciar problemas de causa infecciosa daqueles advindos de deficiências nutricionais ou de falhas no manejo geral ou reprodutivo dos animais. A melhora no diagnóstico de doenças infecciosas e um maior número de informações mais precisas e rápidas para o produtor e para o técnico podem ser conseguidos com emprego de alguns cuidados relativos a coleta e envio de material aos testes requisitados devem ser observados com atenção.bitstream/item/37514/1/CT45.pd

Estimativa da capacidade de suporte das pastagens nativas do Pantanal, sub-região da Nhecolândia.

Este estudo teve como finalidade avaliar as variações mensais da capacidade de suporte de uma área no Pantanal, e propor um cálculo geral de estimativa da capacidade de suporte para as pastagens nativas, com base na produtividade e seletividade das forrageiras existentes nas unidades de paisagem preferidas por bovinos na subregião da Nhecolândia, Pantanal. O estudo foi efetuado numa área de 151 ha, com rebanho de 46 vacas de cria, no período de outubro de 1997 a setembro de 1999. Foram avaliados mensalmente a produção de matéria seca total nas unidades de campo limpo e baixadas, e as respectivas produções de matéria seca total e selecionada dos principais sítios utilizados para pastejo. Um algoritmo foi aplicado para a obtenção das estimativas da capacidade de suporte que foram variáveis entre meses, especialmente no ano hidrológico de 1998/99, considerado "atípico" em relação à distribuição de chuvas. Portanto, a capacidade de suporte de uma invernada não deve seguir regras fixas, e sim flexíveis, de acordo com a proporção de ambientes e condições climáticas de cada propriedade. No entanto, em termos práticos foi proposto cálculo geral anual, que pareceu ser adequado para os anos que apresentam distribuição regular das chuvas.bitstream/item/37425/1/BP27.pd

Postambulatory Hand Swelling (Big Hand Syndrome): Prevalence, Demographics, and Association with Dog Walking

Introduction. Postambulatory hand swelling (PAHS) seems to be common in the general population. There are few mention in the medical literature. The objective were (1) to identify prevalence; (2) to compare gender and age groups; (3) to determine if dog owners and walkers are more or less prone. Materials and Methods. 1009 semirandomly surveys were completed from walkers. Age, gender, and dog ownership were assessed. We discussed, among dog owners, whether or not they walk their dog regularly, whether or not they notice swollen hands after walking, and, if so, if the swelling resolves over 24 hours or persists. Results. 699 females and 410 males, among whom, 28.9% of females but only 16.3% of males reported PAHS (P < 0.001). Surprisingly, those with swelling were statistically younger than those without (49.2 versus 52.8 years, P = 0.003), and dog owners were more likely than nonowners to report swelling (28.1% versus 21.7%; P = 0.015). In terms of persistent swelling, this was observed in twice the percentage of females as males (13.3 versus 6.5%) and tended to involve older subjects (54.0 versus 48.8 years), but with no statistical difference significance. Conclusions. PAHS is a relatively common phenomenon, seemingly more common in females

Seismotectonics of the Southern Apennines and Adriatic foreland: insights on active regional E-W shear zones from analogue modeling

The active tectonics at the front of the Southern Apennines and in the Adriatic foreland is characterized by E-W striking, right-lateral seismogenic faults, interpreted as reactivated inherited discontinuities. The best studied among these is the Molise-Gondola shear zone (MGsz). The interaction of these shear zones with the Apennines chain is not yet clear. To address this open question we developed a set of scaled analogue experiments, aimed at analyzing: 1) how dextral strike-slip motion along a pre-existing zone of weakness within the foreland propagates toward the surface and affects the orogenic wedge; 2) the propagation of deformation as a function of displacement; 3) any insights on the active tectonics of Southern Italy. Our results stress the primary role played by these inherited structures when reactivated, and confirm that regional E-W dextral shear zones are a plausible way of explaining the seismotectonic setting of the external areas of the Southern Apennines

Classificação preliminar das paisagens da sub-região do Abobral, Pantanal, usando imagens de satélite.

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Monitoramento da campilobacteriose genital bovina no Pantanal Sul-Matogrossense: 1996 a 2004.

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Avaliação da estratégia de tratamento parcial do rebanho no controle da mosca-dos-chifres.

A mosca-dos-chifres (MDC) destaca-se dentre os principais ectoparasitos que acometem a pecuária de corte nacional. Seu controle é realizado quase exclusivamente com produtos inseticidas, o que tem levado a sérios problemas de resíduos e resistência. Alternativas não químicas e redução do uso de inseticidas tornam-se essenciais ao controle sustentável deste parasito. O presente estudo avaliou a eficiência do tratamento parcial do rebanho como estratégia de controle da MDC. Quatro experimentos foram conduzidos, utilizando produtos de diferentes classes inseticidas: lactona macrocíclica (ivermectina), fenilpirazol (fipronil), piretróide cipermetrina) e organofosforado+piretróide (clorpirifós+cipermetrina), em formulações pour-on. Em cada experimento, 200 vacas Nelore foram distribuídas em quatro grupos, para avaliação do tratamento de 20%, 50% e 100% do rebanho, além de um grupo não tratado. Contagens periódicas da MDC foram realizadas nos dias 0, 3, 7, 14, 21 e 28 em todos os animais. A eficácia dos produtos nos grupos tratados integralmente foi superior a 90% (exceto pela cipermetrina) ao final da 1ª semana pós-tratamento, sendo de modo geral superior a dos tratados parcialmente nas duas semanas iniciais. Nos grupos tratados parcialmente, a eficácia foi geralmente maior nos grupos com maior frequência de animais tratados. Independente da classe inseticida aplicada e do percentual de animais tratados (20% ou 50%), o tratamento parcial do rebanho apresentou três características principais: a) rápida e acentuada redução das infestações em todo o rebanho, b) menores níveis de redução das infestações e c) menor período de proteção, em relação ao tratamento de todo o rebanho. Apesar da redução no uso de inseticidas e do menor custo, a viabilidade do tratamento parcial do rebanho, como estratégia de controle da MDC, se limita a situações onde um menor nível e período de eficácia sejam aceitáveis, caso contrário, tratamentos adicionais podem ser necessários, comprometendo as vantagens da estratégia. As implicações do tratamento parcial do rebanho no desenvolvimento e manejo da resistência a inseticidas devem ser avaliadas. The horn fly stands out among the main ectoparasites that affect national beef cattle. This livestock pest is controlled almost exclusively by insecticide products, which has led to serious residue and resistance issues. Non-chemical alternatives and reduction of insecticide use are essential for a sustainable control of this parasite. This study evaluated the efficiency of partial herd treatment as a strategy for controlling horn flies. Four experiments were conducted using products from different insecticide classes: macrocyclic lactone (ivermectin) phenylpyrazole (fipronil), pyrethroid (cypermethrin), and an organophosphate-pyrethroid mixture (chlorpyrifos + cypermethrin), in pour-on formulations. In each experiment, 200 Nelore cows were distributed in four groups for evaluation of the treatment of 20, 50, and 100% of the herd, besides an untreated group. Periodic fly counts were performed on days 0, 3, 7, 14, 21, and 28 in all animals. Product efficacy in the full-treated herd exceeded 90% (except for cypermethrin) at the end of the 1st week after treatment, being mostly higher than in partially treated groups in the first two weeks. In the groups partially treated, efficacy was generally higher in the groups with the largest frequency of treated animals. Regardless of the insecticide class and the percentage of treated animals (20% or 50%), the partial treatment of the herd showed three main features: a) fast and marked reduction in infestations throughout the herd, b) lower reduction of horn fly infestations, and c) shorter period of protection, when compared to the full herd treatment. Despite reduction in insecticide use and lower costs, viability of partial herd treatment as a strategy for controlling the horn fly is limited to situations where a lower level and protection period are acceptable; otherwise, the need for additional treatments tends to compromise the advantages of the strategy. The implications of partial herd treatment in the development and management of insecticide resistance should be evaluated.bitstream/item/129471/1/BP125.pd

Emergency-department accesses in home care paediatric patients: Occurrence and risks of use in a six-year retrospective investigation in Northern Italy

Objective To assess the determinants of ED use in paediatric patients enrolled in an Integrated Paediatric Home Care (IPHC) program. Methods A retrospective study was conducted using administrative databases on a cohort of patients enrolled in an IPHC program between January 1st, 2012, and December 31st, 2017, in Northern Italy. ED visits that occurred during the IPHC program were considered. Data were collected considering sociodemographic, clinical and organizational variables. A multivariable stepwise logistic regression analysis was performed. The dependent variable to identify possible associations was ED visit. Results A total of 463 ED visits occurred in 465 children, with an incidence rate of 1. The risk of ED visits significantly increased among children involved in the IPHC program after hospital discharge (OR 1.94). Additionally, the risk of ED visits increased significantly as the duration of IPHC increased (OR 5.80 between 101 and 200 days, to OR 7.84 between 201 and 300 days, OR 12.54 between 301 and 400 days and OR 18.67 to more than 400 days). Conclusion The overall results represent a practical perspective to contribute improving both the service quality of IPHC and reducing low acuity and improper ED use