Soft clustering: An overview

Document clustering has been extensively investigated as a methodology for improving document retrieval process. In Traditional clustering algorithm each documents belongs to exactly one cluster & hence cannot detect the multiple themes of a document where as soft clustering algorithm each document can belong to multiple clusters. This paper gives a comparative study of hard clustering & soft clustering algorithm

Implementation of Congestion Awareness and Adaptivity in Mobile Ad Hoc Networks

Congestion in mobile ad hoc networks leads to transmission delays and packet losses and causes wastage of time and energy on recovery. In the current designs, routing is not congestion adaptive. Routing may let a congestion happen which is detected by congestion control, but dealing with congestion in this reactive manner results in longer delay and unnecessary packet loss and requires significant overhead if a new route is needed. This problem becomes more visible especially in large-scale transmission of heavy traffic such as multimedia data, where congestion is more probable and the negative impact of packet loss on the service quality is of more significance. Routing should not only be aware of, but also be adaptive to, network congestion. Routing protocols which are adaptive to the congestion status of a mobile ad hoc network can greatly improve the network performance. Many protocols which are congestion aware and congestion adaptive have been proposed. In this paper, we present a survey of congestion adaptive routing protocols for mobile ad hoc networks. Ad hoc networks consist of independent self-structured nodes. Nodes utilize a wireless medium for exchange their message or data, as a result two nodes can converse in a straight one to one connection if and only if they are within every other?s transmit range

Glucosamine HCl-based solid dispersions to enhance the biopharmaceutical properties of acyclovir

The objective of the work presented here was to assess the feasibility of using glucosamine HCl as a solid-dispersion (SD) carrier to enhance the biopharmaceutical properties of a BCS class III/IV drug, acyclovir (ACV). The solid-dispersions of acyclovir and glucosamine HCl were prepared by an ethanol-based solvent evaporation method. The prepared formulations characterized by photomicroscopy, scanning electron microscopy (SEM), differential scanning calorimetry (DSC), Fourier transforms infrared spectrophotometry (FTIR), powder x-ray diffractometry (PXRD) and drug content analysis. The functional characterization of ACV-SD was performed by aqueous solubility evaluation, dissolution studies, fasted versus fed state dissolution comparison, ex vivo permeability, and stability studies. Photomicroscopy and SEM analysis showed different surface morphologies for pure ACV, glucosamine HCl and ACV-SD. The physical-chemical characterization studies supported the formation of ACV-SD. A 12-fold enhancement in the aqueous solubility of ACV was observed in the prepared solid dispersions, compared to pure ACV. Results from in vitro dissolution demonstrated a significant increase in the rate and extent of ACV dissolution from the prepared ACV-SD formulations, compared to pure ACV. The rate and extent of ACV permeability across everted rat intestinal membrane were also found to be significantly increased in the ACV-SD formulations. Under fed conditions, the rate and extent of the in vitro dissolution of ACV from the formulation was appreciably greater compared to fasted conditions. Overall, the results from the study suggest the feasibility of utilizing glucosamine HCl as a solid dispersion carrier/excipient for enhancement of biopharmaceutical properties of acyclovir, and similar drugs with low solubility/permeability characteristics

THE NOOTROPIC EFFECT OF SWARNAYOG IN PRESCHOOL CHILDREN

In the world of competition, every child stood in the race for first position. This may exposing the young brains for educational and competitive stress, eventually result in an inability to concentrate and affect memory and the level of cognition. To overcome the situations nootropics are use as brain boosters or memory enhancer. In Ayurveda many Yogas are recommended to use as Medhya (brain booster) in children, Swarnayog is one of them. This study was design to evaluate the nootropic effect of Swarnayog in school children. Normal children without having any physical or mental illness of age group 7-9 yrs was selected. Further they were evaluated for IQ and school performance report. The IQ was not less than 70 and the school performance report was not less than 40% was considered for the study. Total of 60 children were enrolled and randomly divided in two groups A & B. A was treatment and B was control group. The group A was received Swarnayog in the dose of 5 drops per day in morning hours and the group B was received Honey as placebo in the dose of 5 drops per day in morning hours for the period of 30 days. The day 31 children are assessed for general health condition and further on the day 60 children were assessed for academic performance and IQ level. The effect of Swarnayog on group A for academic performance was statistically significant compared with group B, the p value < 0.05= the level of significance. The effect of Swarnayog on group A for IQ was statistically significant compared with group B, the p value < 0.05= the level of significance.   The study was found that group A showed significant effect compared to group B, it showed the positive changes in academic performance & IQ score. Thus the Swarnayog was a good nootropic drug, further study will require for their pharmacodynamic and pharmacokinetic actions

Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti

Bianchi type-I cosmological model in Lyra\u27s manifold is obtained assuming a massless scalar field as the source of gravitational field. Some physical and geometrical properties of the model are discussed.Razvili smo Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti kada je izvor gravitacijskog polja bezmaseno skalarno polje. Raspravljaju se neka fizička i geometrijska svojstva modela

Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti

Bianchi type-I cosmological model in Lyra\u27s manifold is obtained assuming a massless scalar field as the source of gravitational field. Some physical and geometrical properties of the model are discussed.Razvili smo Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti kada je izvor gravitacijskog polja bezmaseno skalarno polje. Raspravljaju se neka fizička i geometrijska svojstva modela

Compaction of microporous amorphous solid water by ion irradiation

We have studied the compaction of vapor-deposited amorphous solid water by energetic ions at 40 K. The porosity was characterized by ultraviolet-visible spectroscopy, infrared spectroscopy, and methane adsorption/desorption. These three techniques provide different and complementary views of the structural changes in ice resulting from irradiation. We find that the decrease in internal surface area of the pores, signaled by infrared absorption by dangling bonds, precedes the decrease in the pore volume during irradiation. Our results imply that impacts from cosmic rays can cause compaction in the icy mantles of the interstellar grains, which can explain the absence of dangling bond features in the infrared spectrum of molecular clouds.Fil: Raut, U.. University of Virginia; Estados UnidosFil: Teolis, B. D.. University of Virginia; Estados UnidosFil: Loeffler, M. J.. University of Virginia; Estados UnidosFil: Vidal, Ricardo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Famá, M.. University of Virginia; Estados UnidosFil: Baragiola, R. A.. University of Virginia; Estados Unido