Complications of in-patient cerebral angiography: Comparison between patients with and without sub arachnoid haemorrhage

Objective: To compare complications of cerebral angiography among patients with and without subarachnoid haemorrhage.Methods: This retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised records of patients undergoing inpatient therapeutic and diagnostic cerebral angiographies from 2001 to 2010. The patients were divided into subarachnoid and non-subarachnoid haemorrhage groups. During the study period no modifications were made to the operational protocol and all patients were subjected to the same procedure and prophylactic care.Results: Of the 93 patients, 42(45.2%) were women and 51(54.8%) were men. The overall mean age was 45.27±16.15 years (range: 4-80 years). The comparison between the two groups regarding new onset of neurological deficit was statistically significant (p=0.001). However, the same comparison regarding drop in Glasgow Coma Scale was statistically not significant (p=0.073).Conclusions: The rate of neurological complications was higher in patients with subarachnoid haemorrhage

Co-creation Model to Design Wearables for Emotional Wellness of Elderly

Ways to influence emotions have always been an area of interest within the scientific community. The objective of this research is to find the role of technology in order to improve emotional wellness for the elderly population. We conducted a qualitative and quantitative study with the help of interviews and a survey. A sample of 24 respondents is selected randomly from the elderly population. The results showed a strong correlation between emotional, psychological and social wellness dimensions and elders comfort with the use of technology. Based on our study, we present a co-creation model to design wearables for monitoring and improving emotional wellness for elderly. There is a need for focused efforts to develop digital interventions for emotional wellness for elderly. It is important to include elders as co-designers to form effective solutions for elderly through a co-creation process

Post-infarct cerebellar cognitive affective syndrome: a case report

Post Infarct cerebellar cognitive affective syndrome is a rare disorder, characterized by cognitive impairment in the domains of memory, language, visuo-spatial functioning and affect after cerebellar stroke. We report a case of young female who developed mood alteration and cognitive disturbance following isolated cerebellar infarct. We, therefore, advocate a potential role of cerebellum in regulation of cognition and behaviour in humans

Aktivitas Antioksidan Dan Penerimaan Panelis Teh Bubuk Daun Alpukat (Persea Americana Mill.) Berdasarkan Letak Daun Pada Ranting

The purpose of this research was to find out the effect of leaf age toward the antioxidant activity and acceptance of avocado leaves herbal tea by panelists. This research used a Completely Randomized Design Experiment with four treatments and four repetitions. The treatment applied toward the avocado leaves herbal tea were P1 : shoots (the first leaves appeared on the top of the branches), P2 : young leaves (the 1st–3rd leaves after the shoot), P3: medium old leaves (the 4th–6th leaves after the shoot), and P4 : old leaves (the 7th–9th leaves after the shoot). Collected data were statistically analized using ANOVA and DNMRT at 5% level. The results showed that the leaves age significantly affected on water content, ash, polyphenol, antioxidant activity and sensory assesment descriptive and hedonic. The choosen treatment from the results of this research was P1 (the first leaves appeared on the top of the branches) that had 5,67% of moisture content, 3,27% of ash content, 7,33% polyphenol content, 54,69 µg/mL of antioxidant activity (IC50). The results of descriptive assesment showed that tea of avocado leaves had yellow brownish color, slightly unpleasent scent, and a little slightly bitter taste. Hedonic assesment showed avocado leaf tea had favored colors, quite fond sense, and the overall assessment of tea was quite favored

FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUTUSAN PETANI PADI SAWAH DALAM MENERAPKAN SISTEM TANAM JAJAR LEGOWO DI KECAMATAN LIMBOTO BARAT KABUPATEN GORONTALO

Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi keputusan petani padi untuk menerapkan sistem tanam jajar legowo di Kecamatan Limboto Barat. Manfaat penelitian bagi Pemerintah dan Petani di Kecamatan Limboto Barat Kecamatan Limboto Barat, sebagai bahan informasi dan bahan pertimbangan dalam meningkatkan produksi padi menggunakan sistem tanam jajar legowo. Penelitian ini dilaksanakan pada bulan September 2020 di Kecamatan Limboto Barat Kabupaten Gorontalo dengan sampel Petani padi sawah. Jenis penelitian survey, data yang digunakandalam penelitian ini data yang dibutuhkan terdiri dari data primer dan data sekunder. Data primer adalah data yang diperoleh langsung dari konsumen melalui observasi, wawancara dan studi pustaka, sedangkan data sekunder adalah data yang dikumpulkan oleh pihak yang berwenang seperti perangkat desa dan lain-lain.Hasil analisis secara parsial diperoleh faktor variabel Umur (X1), Pendidikan (X2) berpengaruh tidak signifikaan, serta Luas Lahan (X3), Lama Bertani (X4), Peran Penyuluh (X5), dan peran Kelompok Tani (X6) berpengaruh positif signifikan. Kemudiandianalisis secara simultan untuk Umur, Pendidikan, Luas Lahan, Lama Bertani, Peran Penyuluh (X5), dan Peran Kelompok Tani (X6) berpengaruh signifikan

Kelayakan Usaha Tani Padi dan Sapi Potong Mendukung Pengembangan Sistem Integrasi Tanaman-Ternak di Kabupaten Merauke, Papua

Kabupaten Merauke merupakan sentra pengembangan tanaman padi dengan potensi produksi bahan kering jerami padi yang dapat dimanfaatkan sebagai pakan sapi potong sebesar 62.123,25 ton/tahun. Kajian bertujuan menganalisis kelayakan usahatani padi dan sapi potong dalam mendukung pengembangan sistem integrasi tanaman-ternak di Kabupaten Merauke. Kegiatan usahatani padi dan sapi potong dilaksanakan secara on farm di lahan petani pada dua lokasi yang berbeda yaitu Tanah Miring dan Kurik. Berdasarkan hasil kajian diperoleh produksi padi dan pertambahan berat badan sapi potong pada pola introduksi dan pola existing, berturut-turut adalah 4,43 ton/ha (PBBH 37,46 kg/ekor) dan 3,71 ton/ha (PBBH 37,1 kg/ekor). Analisis kelayakan usaha tani menunjukkan bahwa baik pola introduksi maupun pola existing diperoleh nilai R/C 1. Tetapi nilai R/C pola introduksi lebih tinggi dibandingkan dengan pola existing. Nilai MBCR 2 menunjukkan bahwa teknologi yang diintroduksikan pada pola introduksi memberikan tambahan keuntungan 2 kali lipat dari pola existing. Disimpulkan bahwa pola introduksi lebih menguntungkan dibandingkan dengan pola existing

The Validity Of 75gms OGTT For Detection Of GDM Keeping 100gms OGTT As Gold Standard

Objective: To determine the validity of 75gms (Oral Glucose Tolerance Test) OGTT for the detection of GDM keeping 100gms OGTT as the gold standard. Methodology: This was a Cross-sectional validation study done at the Mother and Child Health Centre, Pakistan Institute of Medical Sciences, Islamabad. The duration of the study was Six months from the approval of the synopsis. Data was collected from  March 2019 to September 2019. Informed consent for participating in the study was taken from all 205 patients. The patients' bio data along with the hospital registration number was entered pro forma. The patients were assessed initially by History taking and examination. All pregnant women underwent a 75g oral glucose test in the 2nd trimester at 24-28 weeks of gestation. For this, the patients were sent to the MCH laboratory with overnight fasting where FBS was taken and they were given a 75 g glucose drink. Their blood sample was taken at 1-hour and 2-hour interval. Two or more elevated values out of the 3 blood samples were sufficient to diagnose GDM. Laboratory reports were reviewed and data was entered in the performa (attached) by the researcher. All the diagnosed patients were further evaluated for a 100g OGTT dose at the MCH laboratory with overnight fasting. Their FBS was studied and women were given a 100 g glucose drink and blood samples were drawn at an interval of 1, 2 and 3 hours respectively. Out of the 4 blood samples, two or more elevated values were sufficient to diagnose GDM. Lab reports were entered in the Performa. Results: From a total of 205 patients, the sensitivity and specificity of OGTT-75 g for diagnosing GDM were 83.02% and 82.83%. However, positive predictive and negative predictive value for OGTT-75 g was 83.81% and 82% respectively. However, the overall diagnostic accuracy of OGTT-75 g was 82.93%. Conclusion: Results of this study showed that 75 gms OGTT is highly sensitive (83.02%) and specific (82.83%) for the detection/diagnosis of gestational DM. Advanced screening and diagnosis of gestational DM, and its effective treatment not only inhibit adverse perinatal and maternal outcomes but also save the lives of both child and mother from diabetes in future

Impact of Bronchoscopic Lavage and Aggressive Chest Physiotherapy on Clinical Pulmonary Infection Score of Patients of Severe Traumatic Brain Injury

Introduction:  Traumatic brain injury patients present in the emergency room with a variable conscious status depending upon the severity of the injury. The process of aspiration starts from the scene of trauma as the patients with Traumatic brain injury and chest trauma have higher rates of aspiration pneumonia. Materials and Methods:  We conducted a prospective study to assess the impact of bronchoscopy lavage and aggressive chest physiotherapy on the Critical Pulmonary Infection Score of Patients with Severe Traumatic Brain Injury in the Neurocritical Care Unit. Patients with severe traumatic brain injury who met the inclusion criteria were enrolled in the study. Patients of both genders, ages ranging from 05 – 70 years were included in the study. Results:  48 patients who met the inclusion criteria were enrolled in the study. 8 patients expired before 7 days and were excluded from the study. 88% were male and 12 % were females. Out of 40 patients, 30 were ventilated and 10 were managed without ventilation. Brain contusion was the most common CT scan finding. Out of 40 patients, 18 underwent surgical intervention, with decompressive hemicraniectomy being the most commonly performed procedure. Out of 40 patients, 32 patients underwent bronchoscopy. 8 patients out of 32 had more than two sessions of bronchoscopy. Conclusion:  As Critical Pulmonary Infection Score is an important indicator for pneumonia in the neurocritical care unit, the importance of standardized chest care with the help of bronchoscopic lavage and chest physiotherapy in keeping the Critical Pulmonary Infection Score on the lower side can prevent patients from developing life-threatening pneumonia

A Novel Single-Fed Dual-Band Dual-Circularly Polarized Dielectric Resonator Antenna for 5G Sub-6GHz Applications

In this research article, a single-fed dual-band circular polarized (CP) dielectric resonator antenna (DRA) for dual-function communication, such as GPS and WLAN, was made. Initially, the proposed design process was initiated by designing a linearly polarized singly fed-DRA. To attain CP fields, the cross-shape conformal metal strip was optimized to excite the fundamental and the high-order mode in the two frequency bands. The metallic strip (parasitic) was utilized on top of the rectangular DRA to improve and widen the impedance and axial ratio (AR) bandwidth. This step led to a 2.73% improvement on the lower band and an impact of 6.5% on the upper band while on the other side a significant improvement was witnessed in the AR bandwidth in both frequency bands. A prototype was designed and fabricated in order to validate its operations. The measurement outcomes of the proposed antennas authenticated wideband impedance bandwidths of 6.4% and 25.26%, and 3-dB axial ratios (AR) of 21.26% and 27.82% respectively. The prototype is a decent candidate for a global positioning system (GPS) and wireless local area network (WLAN).This project has received funding from the Universidad Carlos III de Madrid and the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska- Curie Grant 801538

Diosgenin normalization of disrupted behavioral and central neurochemical activity after single prolonged stress

Introduction: Post-traumatic stress disorder (PTSD) is a chronic mental illness triggered by traumatic experiences such as wars, natural disasters, or catastrophes, and it is characterized by anxiety, depression and cognitive impairment. Diosgenin is a steroidal sapogenin with known neuroprotective and antioxidant properties. This study aimed to assess the pharmacological potential of diosgenin in a single prolonged stress (SPS) model of PTSD, plus other behavioral models along with any consequent alterations in brain neurochemistry in male mice.Methodology: SPS was induced by restraining animals for 2 h, followed by 20 min of forced swim, recuperation for 15 min, and finally, exposure to ether to induce anesthesia. The SPS-exposed animals were treated with diosgenin (20, 40, and 60 mg/kg) and compared with the positive controls, fluoxetine or donepezil, then they were observed for any changes in anxiety/depression-like behaviors, and cognitive impairment. After behavioral screening, postmortem serotonin, noradrenaline, dopamine, vitamin C, adenosine and its metabolites inosine and hypoxanthine were quantified in the frontal cortex, hippocampus, and striatum by high-performance liquid chromatography. Additionally, animal serum was screened for changes in corticosterone levels.Results: The results showed that diosgenin reversed anxiety- and depression-like behaviors, and ameliorated cognitive impairment in a dose-dependent manner. Additionally, diosgenin restored monoamine and vitamin C levels dose-dependently and modulated adenosine and its metabolites in the brain regions. Diosgenin also reinstated otherwise increased serum corticosterone levels in SPS mice.Conclusion: The findings suggest that diosgenin may be a potential candidate for improving symptoms of PTSD