Screening of three wild edible fruits for their antioxidant potential

The antioxidant properties of three wild edible fruits, viz. Mimusops elengi L.Sp., (Sapotaceae), Cipadessa baccifera (Roth) Miq. (Meliaceae), Bridelia scandens (Roxb.) willd.(Euphorbiaceae) were determined by using  DPPH (2, 2-diphenyl-1-picrylhydrazyl) free radical-scavenging activity, ferric reducing antioxidant property (FRAP), reducing power ability and chelating activity on ferrous ions .The solvent systems used were Acetone, ethanol, methanol and 100% distill water. The different levels of antioxidant activities were found in the solvent systems used

Careif Position Statement on Migration and Mental Health

People have moved from one place to another within the same country or across national borders for millennia. The reasons for such movements have varied, as does the duration for which people migrate. With globalisation and global connections across countries, migration has increased. The process of migration and its impact on the mental health of individuals has been and will remain heterogeneous. The responses of migrants to the process vary, depending upon a number of factors. Individuals may migrate individually, with their families or in groups. They may move to avoid political or religious persecution and seek political asylum in another country (forced migration) or migrate for personal, employment, economic or educational reasons (voluntary migration). Although these two categorisations are often a little more complex than this. Not all migrants will feel negatively affected by migration. People may migrate on a seasonal, recurrent, permanent or temporary basis. It may be within or across generations. Many migrants will never access mental health services, whilst others may use these in varying ways and with diverse requirements or presentations. The experiences and requirements of voluntary and involuntary migrants may differ. Mental health Services may need to ensure that they are accessible and appropriate to all members of society including those who have migrated. This paper makes some suggestions in relation to this

Study of various causes of defaulter among tuberculosis patients under revised national tuberculosis control programme: a prospective analysis of 5235 tuberculosis patients

Background: The world health organization (WHO) declared tuberculosis (TB) a global public health emergency in 1993 and since then intensified its efforts to control the disease worldwide. Poor compliance with tuberculosis (TB) treatment has reportedly been cited as one of the major obstacles which have led to spread of TB and development of multi-drug resistant and extensively drug resistant tuberculosis. The objective is to investigate factors contributing to treatment non-adherence among patients on TB treatment, the results of which might help us to design intervention that would promote compliance.Methods: All TB patients admitted to the Institute were interviewed regarding the past history of anti-tuberculosis treatment (AKT). As per the revised national tuberculosis control programme (RNTCP) guidelines, we defined defaulter as patient who had interrupted AKT for more than 2 months. All the interviewed patients had taken AKT at RNTCP DOT sites. Patient who has taken AKT from private institute were excluded. All the defaulted patients were then interviewed in details. In addition to the personal and socio-demographic data, treatment history was recorded in details along with reasons for stopping treatment.Results: Among 5235 TB patients, 405 (7.7%) were found to have a past history of AKT interruption. The highest number of treatment interrupters were in the age group 21 to 50 years (n=309), constituting nearly 76.29% of all the patients studied. The most common reason stated was AKT-induced side effects (42.2%) a feeling of early improvement (33.3%) and followed by migration for work (9.6%).Conclusions: Present study concludes that the most common cause of defaulters amongst tuberculosis patients are adverse effects, feeling of early improvement and migration.

A Low Rhodium Content Smart Catalyst for Hydrogenation and Hydroformylation Reactions

Abstract: This paper describes the preparation, broad characterization and study of activity in hydrogenation and hydroformylation reactions of an easily produced 0.18% Rh/Al2O3. Analytical studies on fresh and recycled samples shed light on the smart properties of such catalyst. Results showed high activity as well as fine/excellent chemoselectivity or regioselectivity, characteristics that may suggest a wide range of applicability. Graphic Abstract: The low metal content catalyst 0.18% Rh/Al2O3 was very active in both hydrogenation and hydroformylation reactions so providing intermediates for valuable APIs, as Nabumetone and Eletriptan, and a fragrance with a fresh, green-floral smell, that recalls scent of lily of the valley.[Figure not available: see fulltext.

UK perspective on the changing landscape of non-invasive cardiac testing.

Objective: To document UK rates of exercise treadmill testing, functional stress testing and CT coronary angiography (CTCA). Specific aims were to determine how rates have changed in the context of changing guideline recommendations within the UK and to identify regional inequalities in the utilisation of testing modalities. Secondary objectives were to compare these trends with national data on revascularisation. Methods: 159 acute National Health Service trusts were served Freedom of Information (FOI) requests to provide total numbers of CTCA and functional imaging tests for each financial year from 2011-2012 to 2016-2017. Results: The FOI requests yielded data from 88% of Trusts, increasing from 81.9% in 2011-2012% to 92.1% in 2016-2017. Exercise treadmill tests (ETTs) were performed by over 97% of Trusts. ETT was the most commonly performed diagnostic test in the UK across the study period despite declining by 8.4%. Utilisation of non-invasive stress imaging tests increased by 80.9% during the same period. Myocardial perfusion scintigraphy and stress echocardiography increased by 25.8% and 73.9%, respectively. The 268% increase in CTCA scans was yet greater. Trends in test utilisation during the study period showed important regional differences between devolved nations. Comparably, only small changes in rates of invasive coronary angiography and revascularisation have been reported during the study period. Conclusion: Non-invasive imaging in UK Trusts has increased substantially since 2010 with only a small decline in use of the ETT and minimal changes in rates of invasive coronary angiography and revascularisation in the same time period

Tinea incognito with unjustified use of potent Topical Corticosteroids: a case series

Topical corticosteroids prescribed for various dermatological conditions, if used haphazardly have their adverse effects too, like aggravation of underlying infections - tinea, herpes etc. Tinea incognito is a fungal infection of skin masked and often exacerbated by application of topical immunosuppressive or steroid agent. Tinea incognito results because local physicians/chemists might mistake tinea with a simple rash. Availability of a topical steroid cream as an over the counter (OTC) drug is also one of the causes. Once it is diagnosed (clinically with or without KOH mount preparation), it should be thoroughly treated with oral and topical antifungal agents. Four cases presenting to Dermatology OPD VSGH with chief complaints of itching and aggravation of existing lesions due to application of potent topical corticosteroids like Clobetasol and Beclomethasone have been discussed here. They were diagnosed as cases of Topical Corticosteroids induced Tinea Incognito. The patients were recovering with oral and topical antifungals prescribed by dermatologist. These were also reported to nearest ADR Monitoring Centre under PvPI with Probable causality according to WHO UMC Criteria for Causality Assessment. The wide use of topical corticosteroids is due to its immediate symptomatic relief. However, the normal presentation of superficial infection gets altered with their inappropriate use. Lack of awareness among population, steroid abuse by local physicians or no strict regulations for local chemist shops have led to its inappropriate use. Its incidence ranges from 5-15%. These figures point towards the fact that implementation of appropriate regulations for the safe use of topical corticosteroids is essential

pH of soil of Majalgaon command area (Jayakwadi project stage-III), India

Present paper deals with the study of pH of soil of Majalgoan command area, India. pH varied from 7.55 to 8.98 in different soil types and showed increased trend with depth in most of the profiles