Three-dimensional imaging is a novel and reliable technique to measure total body surface area

Objective: The aim of this study was to explore the diverse clinimetric aspects of three-dimensional imaging measurements of TBSA in clinical practice compared with the methods currently used in clinical practice (i.e., the rule of nines and palm method) to measure TBSA in clinical practice. Method: To assess reliability, two independent researchers measured the TBSAs of 48 burn patients using Artec MHT™ Scanner and software. Subsequently, a resident and burn specialist estimated the TBSA of the same wounds using the rule of nines and palm method. Results: Three-dimensional imaging showed excellent inter-observer reliability, with an intra-class correlation coefficient (ICC) of 0.99, standard error of measurement (SEM) of 0.054, and limits of agreement (LoA) of ±0.15 × the mean TBSA (between the measurements of two researchers). The inter-observer reliability of the methods used in current clinical practice was less reliable, with an ICC of 0.91, SEM of 0.300 and LoA of ±0.78 × the mean TBSA. The inter-observer reliability was least reliable between three-dimensional imaging and the residents compared with the burn specialists for the estimated TBSA, with an ICC of 0.68, SEM of 0.69 and LoA of ±1.49 × the mean TBSA. Conclusion: The inter-observer reliability of three-dimensional imaging was superior compared with the rule of nines and palm method

Patterns and predictors of burn scar outcome in the first 12 months after burn: The patient's perspective

Objective: This study aimed to provide insight into the patterns and factors that predict burn scar outcomes at 3, 6 and 12 months after burn. Methods: The Patient and Observer Scar Assessment Scale (POSAS) was used to assess the scar formation of each patient. Structural equation modelling was used. The predictor variables used in this study were sex, three age categories, TBSA, depth of the wound and cause of the burn. Results: The POSAS patient total and individual item scores demonstrated a statistically significant decrease in the first 12 months after burn, except for the relief item. Male patients had a lower total and items scores (better scar quality) for pain and pruritus compared with female patients. Full thickness burns had a higher scores for pruritus, pliability, thickness and relief compared to the partial-thickness burns. Ages younger than 5 years, higher TBSA values and flame burns were predictors of various POSAS items at 3 and 6 months after burn. Conclusion: The POSAS patient total and individual item scores demonstrated a statistically significant improvement in the scar quality in the first 12 months after burn, except for the relief. Sex, age, depth of the wound, the percentage of TBSA and flame burns were predictors of various POSAS patient items at 3, 6 and 12 months after burn

Usability and effectiveness of Suprathel® in partial thickness burns in children

Trauma Surger

Alginate: Pharmaceutical and Medical Applications

Due to their outstanding properties in terms of mild gelation conditions and simple functionalization, biocompatibility, low toxicity, biodegradability, non-antigenicity and chelating ability, as well as relatively low cost, alginates have been widely used in a variety of biomedical applications including tissue engineering and drug delivery systems. Smart alginate hydrogels for on-demand drug release in response to environmental stimuli and 3D bioprinting will play an important role in the future. These and the introduction of appropriate cell interactive features will be crucial for many tissue engineering applications. The focus of the present chapter is to highlight the great potential of the alginates as biomaterial for biomedical applications and to discuss the role that alginate-based materials are likely to play in biomedical applications in the future.info:eu-repo/semantics/publishedVersio