Dampak Pengelolaan Tinja Terpadu Terhadap Infeksi Ascaris Lumbricoides Di Daerah Kota (I)

A study on the health impact of integrated environmental sanitary management was done in the village of Pisangan Baru, East Jakarta. As an indicator of health status, Ascaris lumbricoides infection in school children was used. The result of the study before the intervention showed that the prevalence of A. lumbircoides infec­tion in school children who lived in RW 06 Pisangan Baru was 46.3% and 45.7% who lived in RW 013. Ex­amination of sewage water in ditches showed 42% positive with A. lumbircoides eggs in RW 06 and 30% in RW 013. The result of soil examination in RW06 was 18% positive while in RW 013 was 20% positive with tion of sewage water in ditches showed 42% positive with A. lumbricoides eggs in RW 06 and 30% in RW 013. The result of soil examination in RW06 was 18% positive while in RW 013 was 20% positive with A. lumbricoides eggs. The result of a post - intervention study showed a prevalence of 33.7% in school children from RW 06 and 25.8% from RW 013, whereas the sewage water examination in ditches around RW 06 was 14% positive with A. lumbricoides eggs and 24% in RW 013. The soil ecamination in RW 06 revealed 6% positive while in RW 013 was 16% positive with A. lumbricoides eggs. The result of the study showed that the impact of intervention was clearly evident on the waste water contamination but not on the reinfection of school children with A. lumbricoides as well as the degree of soil contamination

Therapeutic effects of Glycyrrhiza glabra aqueous extract ointment on cutaneous wound healing in Sprague Dawley male rats

Glycyrrhiza glabra has been reported to have wide applications in the treatment of many human diseases. However, its traditional use in the treatment of wounds has not been validated by any scientific study. Also, its safety in the management of cutaneous wound conditions requires attention. The purpose of the experiment was to investigate the wound healing potential of G. glabra aqueous extract ointment. In vivo design, 120 Sprague Dawley male rats were used. After creating the cutaneous wound, the animals were randomly divided into four groups: untreated control, treatment with Eucerin ointment, treatment with 3 tetracycline ointment, treatment with 3 G. glabra aqueous extract ointment (3 g of G. glabra aqueous extract + 97-g base ointment). At days 10, 20, and 30 after creating the wound, for histopathological and biochemical analysis of the cutaneous wound healing trend, a section was prepared from all dermal thicknesses. The data were analyzed using one-way ANOVA followed by Duncan post hoc test of SPSS-22 software. At days 10, 20, and 30, G. glabra aqueous extract ointment could significantly (p ≤ 0.05) decrease the level of the wound area, total cell, macrophage, lymphocyte, and neutrophil, and enhance the level of wound contracture, fibrocyte, hexuronic acid, and hydroxyproline as compared with the basal ointment and control groups. In conclusion, the present study has demonstrated that the aqueous extracts of G. glabra have properties that render them capable of promoting accelerated wound-healing activity compared with other groups. © 2019, Springer-Verlag London Ltd., part of Springer Nature