2 research outputs found

    The use of reverse abdominoplasty for treatment of chemical burn in the thoracoabdominal region

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    Chemical burn is a challenge owing to its severity compared to thermal burns. The depth and extent of lesions in different areas of the body lead us to look for different possibilities for the best treatment of the patient. A reverse abdominoplasty surgical technique was proposed; this involves a skin flap that could reduce the exposed area of a chemical burn. The result was satisfactory, reducing the patient's treatment, surgical and hospitalization time, highlighting the proposed technique as an important tool for thoracoabdominal reconstruction

    PLLA/Triethyl citrate membrane as an alternative for the treatment of skin wounds

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    Bioresorbable polymers can be applied as membranes to sustain and guide cell growth through the regeneration process. This study evaluated poly(acid lactide), PLLA, membranes with addition of 10% triethyl citrate as skin wound healing in Wistar rats. Initially a 2cm² skin wound was exercised of the back of 24 animals. The animals were divided into two groups: treated, whose the polymer membrane was implanted, and control, in which the wound was kept exposed. The results obtained after 1, 3, 7 and 15 days showed an inflammatory response more satisfactory in the implanted wounds, with early repair and collagen more organized when compared to exposed wounds. In addition to, the protected areas showed no irritant inflammatory response which could be attributed to the membrane. Thus, we conclude that the PLLA/Triethyl citrate membrane has effectively protected the wounds, allowing the repair and presenting itself as a promising skin dressing.Polímeros sintéticos biorreabsorvíveis podem ser utilizados sob a forma de membranas para sustentar e guiar o crescimento celular, através do processo de reparação tecidual. Este trabalho avaliou membranas de poli(ácido lático), PLLA, com adição de 10% de trietil-citrato usadas como curativos de feridas cutâneas agudas em ratos Wistar. Inicialmente uma ferida de 2cm² foi provocada na região dorsal de 24 animais. Estes foram divididos em 2 grupos: tratamento, nos quais as feridas foram recobertas pela membrana polimérica e controle, com feridas permanecendo cruentas. Os resultados obtidos em 1, 3, 7 e 15 dias mostraram uma resposta inflamatória mais satisfatória nas feridas protegidas pelas membranas, com reparação precoce e colágeno mais organizado quando comparadas com as áreas incialmente mantidas sem proteção. Além do que, as áreas protegidas pelas membranas não mostraram alterações inflamatórias irritativas que pudessem ser imputadas ao uso da membrana polimérica. Diante disso, conclui-se que a membrana de PLLA/Trietil-citrato protegeu efetivamente as feridas, permitindo o processo de reparação e mostrando-se promissora como curativo cutâneo.798806Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq
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