Pierre Lombart (1612/1613-1681)

La découverte au Minutier central des notaires parisiens du testament de Pierre Lombart (mort à Paris le 30 octobre 1681) et de l’inventaire de ses biens dressé après son décès, ici publiés, sert de prétexte à une évocation de la carrière de ce graveur talentueux aujourd’hui oublié. Formé en France, sa qualité de protestant l’entraîne en Angleterre où il travaille notamment à l’illustration des œuvres de Virgile et remporte un grand succès en gravant une suite de « Comtesses anglaises » d’après Van Dyck. De retour à Paris en 1663, il travaille à l’interprétation de peintures catholiques et de portraits de personnages souvent de la mouvance calviniste. Il entre cependant à l’Académie royale de peinture et sculpture en septembre 1673.Pierre Lombart, a talented printmaker who died in Paris October 30, 1681, has since fallen into obscurity, but the present edition of his will and post mortem inventory recently discovered in the central notarial records (Minutier central des notaires is a chance to retrace his career. Lombart trained in France but his reformed faith drove him to England; there he illustrated Virgil and his series of « English Countesses » after Van Dyck was a resounding success. He came back to Paris in 1663, and there worked on the reinterpretation of catholic paintings and portraits, often of Calvinist personalities. He did however join the Académie royale de peinture et sculpture in September 1673

Cardiovascular ultrasound exploration contributes to predict incident atrial fibrillation in arterial hypertension: the Campania Salute Network

Interaction of cardiovascular (CV) risk factors with structural and hemodynamic alterations as combined promoters of atrial fibrillation (AF) is not yet well studied. We designed an observational, longitudinal, retrospective study to predict risk of incident AF by combination of CV risk profile, target organ damage and therapy in hypertensive patients

Effectiveness of subcutaneous implantable cardioverter-defibrillator testing in patients with hypertrophic cardiomyopathy

Background Subcutaneous ICD (S-ICD) is a promising option for Hypertrophic Cardiomyopathy (HCM) patients at risk of Sudden Cardiac Death (SCD). However, its effectiveness in terminating ventricular arrhythmias in HCM is yet unresolved. Methods Consecutive HCM patients referred for S-ICD implantation were prospectively enrolled. Patients underwent one or two attempts of VF induction by the programmer. Successful conversion was defined as any 65 J shock that terminated VF (not requiring rescue shocks). Clinical and instrumental parameters were analyzed to study predictors of conversion failure. Results Fifty HCM patients (34 males, 40 ± 16 years) with a mean BMI of 25.2 ± 4.4 kg/m2 were evaluated. Mean ESC SCD risk of was 6.5 ± 3.9% and maximal LV wall thickness (LVMWT) was 26 ± 6 mm. In 2/50 patients no arrhythmias were inducible, while in 7 (14%) only sustained ventricular tachycardia was induced and cardioverted. In the remaining 41 (82%) patients, 73 VF episodes were induced (1 episode in 14 and > 1 in 27 patients). Of these, 4 (6%) spontaneously converted. In 68/69 (98%) the S-ICD successfully cardioverted, but failed in 1 (2%) patient, who needed rescue defibrillation. This patient was severely obese (BMI 36) and LVMWT of 25 mm. VF was re-induced and successfully converted by the 80 J reversed polarity S-ICD. Conclusions Acute DT at 65 J at the implant showed the effectiveness of S-ICD in the recognition and termination of VT/VF in all HCM patients except one. Extreme LVH did not affect the performance of the device, whereas severe obesity was likely responsible for the single 65 J failure

Association Between Device-Detected Sleep-Disordered Breathing and Implantable Defibrillator Therapy in Patients With Heart Failure

BACKGROUND Sleep-disordered breathing is highly prevalent in heart failure (HF) and has been suggested as a risk factor for malignant ventricular arrhythmias. The Respiratory Disturbance Index (RDI) computed by an implantable cardioverter-defibrillator (ICD) algorithm accurately identifies severe sleep apnea.OBJECTIVES In the present analysis, the authors evaluated the association between ICD-detected sleep apnea and the incidence of appropriate ICD therapies in patients with HF.METHODS We enrolled 411 HF patients who had received an ICD endowed with an algorithm that calculates the RDI each night. In this analysis, the weekly mean RDI value was considered. The endpoint was the first appropriate ICD shock.RESULTS The median follow-up was 26 months (25th to 75th percentile: 16-35 months). During follow-up, 1 or more ICD shocks were documented in 58 (14%) patients. Patients with shocks were younger (age 66 +/- 13 years vs 70 +/- 10 years; P = 0.038), and had more frequently undergone implantation for secondary prevention (21% vs 10%; P = 0.026). The maximum RDI value calculated during the entire follow-up period did not differ between patients with and without shocks (55 +/- 15 episodes/h vs 54 +/- 14 episodes/h; P = 0.539). However, the ICD-detected RDI showed considerable variability during follow-up. The overall median of the weekly RDI was 33 episodes/h (25th to 75th percentile: 24-45 episodes/h). A time-dependent Cox regression model revealed that a continuously measured weekly mean RDI of $45 episodes/h was independently associated with shock occurrence (HR: 4.63; 95% CI: 2.54-8.43; P < 0.001), after correction for baseline confounders (age, secondary prevention).CONCLUSIONS In HF patients, appropriate ICD shocks were more likely to be delivered during periods when patients exhibited more sleep-disordered breathing. (Arrhythmias Detection in a Real World Population [RHYTHM DETECT]; NCT02275637) (J Am Coll Cardiol EP 2022;8:1249-1256) (c) 2022 by the American College of Cardiology Foundation