N-[(2-Chloro-8-methyl­quinolin-3-yl)meth­yl]-4-meth­oxy­aniline

In the title compound, C18H17ClN2O, the quinoline ring system is essentially planar; the r.m.s. deviation for the non-H atoms is 0.04 Å with a maximum deviation from the mean plane of 0.026 (4) Å for the C atom bonded to the –CH2– group. The meth­oxy-substituted benzene ring forms a dihedral angle of 70.22 (4)° with this ring system. The crystal structure can be described as zigzag layers in which the quinoline ring systems are parallel to (011) and molecules are connected via inter­molecular N—H⋯N hydrogen bonds, forming chains along [100]. The crystal studied was an inversion twin with a 0.86 (5):0.14 (5) domain ratio

A DMAP-catalyzed mild and efficient synthesis of 1,2-dihydroquinazolines via a one-pot three-component protocol

International audienceAn efficient and simple method for the synthesis of 1,2-dihydroquinazolines catalyzed by 4-(N,N-dimethylamino) pyridine (DMAP) from readily available aromatic or heteroaromatic aldehydes, 2-aminobenzophenone, and ammonium acetate under mild conditions is described. The scope and limitations of the method are discussed

2-Hy­droxy-N-(4-meth­oxy­benz­yl)-4-nitro­anilinium chloride

The crystal structure of the title compound, C14H15N2O4 +·Cl−, can be described as being composed of layers containing both cations and anions that are staggered along [010]. Two types of the hydrogen bonds are observed, viz. cation–anion and cation–cation. The chloride anions are acceptors of the strong hydrogen bonds donated by the secondary amine and the hy­droxy groups. The packing is also stabilized by weak C—H⋯O inter­molecular hydrogen bonds. An intra­molecular N—H⋯O inter­action also occurs

Diethyl 2,6-dimethyl­pyridine-3,5-dicarboxyl­ate at 100 K

In the structure of the title compound, C13H17NO4, the packing is stabilized by weak C—H⋯O and C—H⋯π inter­actions, resulting in the formation of a three-dimensional network

Cd(NO3)2.4H2O Catalyzed One-Pot Synthesis of 1,4-Dihydropyridine and Polyhydroquinoline Derivatives through the Hantzsch Multicomponent Condensation

International audienceThe synthesis of various 1,4-dihydropyridine and polyhydroquinoline derivatives was achieved in good to excellent yields using cadmium (II) nitrate as catalyst to promote the classical and modified Hantzsch conditions in good yields under mild conditions

Synthesis of Some New Pyrano[2,3-b]quinolines from 2-chloro-3- formylquinolones and Meldrum’s Acid

International audienc

Phenylboronic acid as an efficient and convenient catalyst for a three-component synthesis of tetrahydrobenzo[b]pyrans

International audiencePhenylboronic acid, a non-toxic compound, is used as catalyst for an efficient, rapid, and one-pot three-component synthesis of tetrahydrobenzo[b]pyrans in good to excellent yields. This new procedure has the advantages of operational simplicity, shorter reaction time, higher yields and minimum pollution of the environment