Synthesis of some 3-(2-substituted sulfanyl-imidazo [2,1-b][1,3,4] thiadiazol-6-yl)-chromen-2-one and its derivatives

454-458A series of 3-(2-substituted sulfanyl-imidazo [2,1-b][1,3,4] thiadiazol-6-yl)-chromen-2-ones (3) have been synthesized from 3-(2-bromo acetyl) chromen-2-ones 1 and 2-amino-5-thio substituted[1,3,4]thiadiazole 2 in anhydrous ethanol. The 7,8-benzo analogs of 3-(2-substituted sulfanyl-imidazo[2,1-b][1,3,4] thiadiazol-6-yl)-chromen-2-ones 5 have been synthesized under similar conditions. All the synthesized compounds have been characteriszed by analytical and spectral data

Prediction of Alzheimer Disease using LeNet-CNN model with Optimal Adaptive Bilateral Filtering

Alzheimer's disease is a kind of degenerative dementia that causes progressively worsening memory loss and other cognitive and physical impairments over time. Mini-Mental State Examinations and other screening tools are helpful for early detection, but diagnostic MRI brain analysis is required. When Alzheimer's disease (AD) is detected in its earliest stages, patients may begin protective treatments before permanent brain damage has occurred. The characteristics of the lesion sites in AD affected role, as identified by MRI, exhibit great variety and are dispersed across the image space, as demonstrated in cross-sectional imaging investigations of the disease. Optimized Adaptive Bilateral filtering using a deep learning model was suggested as part of this study's approach toward this end. Denoising the pictures with the help of the suggested adaptive bilateral filter is the first stage (ABF). The ABF improves denoising in edge, detail, and homogenous areas separately. After then, the ABF is given a weight, and the Adaptive Equilibrium Optimizer is used to determine the best possible value for that weight (AEO). LeNet, a CNN model, is then used to complete the AD organization. The first step in using the LeNet-5 network model to identify AD is to study the model's structure and parameters. The ADNI experimental dataset was used to verify the suggested technique and compare it to other models. The experimental findings prove that the suggested method can achieve a classification accuracy of 97.43%, 98.09% specificity, 97.12% sensitivity, and 89.67% Kappa index. When compared against competing algorithms, the suggested model emerges victorious

Characterization of Srikurmum and Navaladi Beach Placer Minerals

Two different beach placer samples from Srikurmum of Andhra Pradesh and Navaladi of Tamilnadu were collected and characterized in terms of their total heavy mineral content by heavy media as well as magnetic separation studies. Navaladi beach placer sample contains higher amounts of total heavy minerals than that of the Srikur-mum beadh. Mineralogical analysis on both the samples revealed high amounts of garnet and minor quantities of ilmenite. The particle size of garnet is coarser than that of ilmenite. EPMA results indicated that garnet is of almandine variety. The Eastern Ghats metarnotphic belt, covering both the areas, is considered to be the source of these beach placer minerals

Value Addition of Indian Iron Ore Fines by Column Flotation - Few Case Studies

The Government of India highlighted Processing and utili-zation of iron ore fines as a prerequisite to meet the domestic raw material requirements for the projected 110 million tonnes of domestic steel production by the year 2019-20 in the National Steel Policy announced in Nov-ember 2005. This would require 190 million tonnes of iron ore. The depletion of high grade iron ore and increased generation of fines during mining and handling and demand for high grade iron ore fines for export has necessitated the processing of low to medium grade fines. The R&D efforts undertaken at NML-Madras Centre, India in this direction have been highlighted. Flotation in general and Column Flotation in particular appear to be promising in addressing this problem. This would also mitigate the environmental problem created by the dumping of huge quan-tities of low and medium grade iron ore fines. Three case studies involving iron ore fines of varying silica and alumina content from Goa and Bellary-Hospet regions of India were discussed. The results clearly indicate the feasibility and significance of flotation process in treat-ing the fines to obtain marketable concentrates

Alteration characteristics of manavalakurichi beach placer illmenite, Tamilnadu.

The mineralogy and alteration characteristics of beach placer ilmenite from the Manavalakurichi coast were investigated by optical microscopy and electron probe microanalysis. Mineral chemistry by electron probe micro-analysis indicated ;enrichment of TI02, MgO, AI203, Cr203, Si02. K20, V205,. CaO and Na20 in the altered products ofilmenitc:. while there was a loss of iron oxide, maganesc oxide and zinc oxide from the ilmenite grains during weathering leading to leucoxen

Beneficiation of a Low Grade Limestone by Flotation Column

Beneficiation of a Low-grade limestone sample from Salem, Tamilnadu was carried out by pilot scale flotation column. Mineralogical studies have revealled that quartz, freldspar, pyroxene and biotitic as gangue minerals while pyrite, in trace quantitiew, appear as opaque along with dominating calcite. Reverse flotation was tried using two different commercial amines viz. Chem750F and Flotamine-D. The studies clearly suggest that it is possible to produce a limestone concentrat assying around 96-97% of CaCO3 with less than 1% SiO2

Processing of iron ore fines by column flotation – Part I & part II

The Government of India highlighted Processing and utilization of iron ore fines as a pre-requisite to meet the domestic raw material requirements for the projected 110 million tonnes of domestic steel production by the year 2019-20 in the National Steel Policy announced in November 2005. This would require 190 million tonnes of iron are. The depletion of high grade iron are and increased generation of fines during mining and handling and demand for high grade iron are fines for export has necessitated the processing of low to medium grade fines. The R&D efforts undertaken at NML-Madras Centre, India in this direction have been highlighted. Flotation in general and Column Flotation in particular appear to be promising in addressing this problem. This would also mitigate the environmental problem created by the dumping of huge quantities of low and medium grade iron are fines. Three case studies involving iron ore fines of varying silica and alumina content from Goa and Bellary-Hospet regions of India were discussed. The results clearly indicate the feasibility and significance of flotation process in treating the fines to obtain marketable concentrates

Mineralogy and Geochemistry of a low grade iron ore sample from Bellary-Hospet sector, India and their implications on beneficiation.

Detailed studies were conducted on iron ores of Bellary-Hospet sector using microscope, XRD, TG, and EPMA techniques. The results indicate that hematite is the major iron oxide mineral with minor amounts of goethite, magnetite, martite and limonite with quartz and clay as major gangue. There is no evidence of the presence of any iron silicate and iron carbonate minerals. Trace amounts of pyrite were observed under the microscope and is the only iron sulphide phase. Microscopic studies also indicated that most of the quartz grains are present as inclusions within the hematite and magnetite grains. XRD studies revealed hematite as the major mineral with subordinate amounts of goethite, quartz and kaolinite confirming to the microscopic findings. Qualitative mapping and quantitative EPMA studies on these ores indicated the presence of gibbsite as the only alumina bearing phase and apatite as phosphorous bearing mineral. Traces of alumina, present as solid solution in the iron oxide minerals, has also contributed Al2O3 to the ores. Electron microscopic studies revealed that gibbsite grains are in the size range of 10 to 50 microns and are intimately and intricately associated with the iron oxide phases. Major elemental analyses of 47 representative iron ore samples of various types were analyzed to deduce the source of silica and alumina’s contributing phases in the ore and their interrelationships. The geochemistry data revealed negative correlation of Fe2O3 with silica and alumina thus indicating there is no iron silicatephase as well as alumina contribution from iron oxide minerals in the form of solid solution is insignificant. Positive correlation of silica with alumina indicates that the clay is the major contributing mineral for both the silica and alumina phase and presence of gibbsite. The role of gangue minerals and the interrelationship of silica, alumina and iron oxide, with reference to beneficiation are discussed. Jigs and heavy media cyclones for this type of ores can be used but at the cost of poor yield because of complex nature of alumina distribution. As long as alumina and silica mineralization is not too fine and the ore composed of magnetite/hematite with coarse grained quartz, magnetic route is the most effective. Since the quartz grains are too fine and their distribution is very complex for the Bellary-Hospet sector ores, flotation in general and column flotation in particular seems to be more effective