Automated Screening for Three Inborn Metabolic Disorders: A Pilot Study

Background: Inborn metabolic disorders (IMDs) form a large group of rare, but often serious, metabolic disorders. Aims: Our objective was to construct a decision tree, based on classification algorithm for the data on three metabolic disorders, enabling us to take decisions on the screening and clinical diagnosis of a patient. Settings and Design: A non-incremental concept learning classification algorithm was applied to a set of patient data and the procedure followed to obtain a decision on a patient’s disorder. Materials and Methods: Initially a training set containing 13 cases was investigated for three inborn errors of metabolism. Results: A total of thirty test cases were investigated for the three inborn errors of metabolism. The program identified 10 cases with galactosemia, another 10 cases with fructosemia and the remaining 10 with propionic acidemia. The program successfully identified all the 30 cases. Conclusions: This kind of decision support systems can help the healthcare delivery personnel immensely for early screening of IMDs

Initial stages of cavitation damage and erosion on copper and brass tested in a rotating disk device

In view of the differences in flow and experimental conditions, there has been a continuing debate as to whether or not the ultrasonic method of producing cavitation damage is similar to the damage occurring in cavitating flow systems, namely, venturi and rotating disk devices. In this paper, the progress of cavitation damage during incubation periods on polycrystalline copper and brass tested in a rotating disk device is presented. The results indicate several similarities and differences in the damage mechanism encountered in a rotating disk device (which simulates field rotary devices) and a magnetostriction apparatus. The macroscopic erosion appears similar to that in the vibratory device except for nonuniform erosion and apparent plastic flow during the initial damage phase

The effects of random path fluctuations on the accuracy of laser ranging systems

The precision of satellite ranging systems, limited in part by atmospheric refraction and scattering, is examined. The effects of atmospheric turbulence on the accuracy of single color and multicolor ranging systems is discussed. The statistical characteristics of the random path length fluctuations induced by turbulence are examined. Correlation and structure functions are derived using several proposed models for the variations of the optical path length. For single color systems it is shown that the random path length fluctuations can limit the accuracy of a range measurement to a few centimeters. Two color systems can partially correct for the random path fluctuations so that in most cases their accuracy is limited to a few millimeters. However, at low elevation angles and over long horizontal paths two color systems can also have errors approaching a few centimeters

Biology of Sexual Dysfunction

Sexual activity is a multifaceted activity, involving complex interactions between the nervous system, the endocrine system, the vascular system and a variety of structures that are instrumental in sexual excitement, intercourse and satisfaction. Sexual function has three components i.e., desire, arousal and orgasm. Many sexual dysfunctions can be categorized according to the phase of sexual response that is affected. In actual clinical practice however, sexual desire, arousal and orgasmic difficulties more often than not coexist, suggesting an integration of phases. Sexual dysfunction can result from a wide variety of psychological and physiological causes including derangements in the levels of sex hormones and neurotrensmitters. This review deals with the biology of different phases of sexual function as well as implications of hormones and neurotransmitters in sexual dysfunctio

THE-FAME: THreshold based Energy-efficient FAtigue MEasurment for Wireless Body Area Sensor Networks using Multiple Sinks

Wireless Body Area Sensor Network (WBASN) is a technology employed mainly for patient health monitoring. New research is being done to take the technology to the next level i.e. player's fatigue monitoring in sports. Muscle fatigue is the main cause of player's performance degradation. This type of fatigue can be measured by sensing the accumulation of lactic acid in muscles. Excess of lactic acid makes muscles feel lethargic. Keeping this in mind we propose a protocol \underline{TH}reshold based \underline{E}nergy-efficient \underline{FA}tigue \underline{ME}asurement (THE-FAME) for soccer players using WBASN. In THE-FAME protocol, a composite parameter has been used that consists of a threshold parameter for lactic acid accumulation and a parameter for measuring distance covered by a particular player. When any parameters's value in this composite parameter shows an increase beyond threshold, the players is declared to be in a fatigue state. The size of battery and sensor should be very small for the sake of players' best performance. These sensor nodes, implanted inside player's body, are made energy efficient by using multiple sinks instead of a single sink. Matlab simulation results show the effectiveness of THE-FAME.Comment: IEEE 8th International Conference on Broadband and Wireless Computing, Communication and Applications (BWCCA'13), Compiegne, Franc

AM-DisCNT: Angular Multi-hop DIStance based Circular Network Transmission Protocol for WSNs

The nodes in wireless sensor networks (WSNs) contain limited energy resources, which are needed to transmit data to base station (BS). Routing protocols are designed to reduce the energy consumption. Clustering algorithms are best in this aspect. Such clustering algorithms increase the stability and lifetime of the network. However, every routing protocol is not suitable for heterogeneous environments. AM-DisCNT is proposed and evaluated as a new energy efficient protocol for wireless sensor networks. AM-DisCNT uses circular deployment for even consumption of energy in entire wireless sensor network. Cluster-head selection is on the basis of energy. Highest energy node becomes CH for that round. Energy is again compared in the next round to check the highest energy node of that round. The simulation results show that AM-DisCNT performs better than the existing heterogeneous protocols on the basis of network lifetime, throughput and stability of the system.Comment: IEEE 8th International Conference on Broadband and Wireless Computing, Communication and Applications (BWCCA'13), Compiegne, Franc

Distance Aware Relaying Energy-efficient: DARE to Monitor Patients in Multi-hop Body Area Sensor Networks

In recent years, interests in the applications of Wireless Body Area Sensor Network (WBASN) is noticeably developed. WBASN is playing a significant role to get the real time and precise data with reduced level of energy consumption. It comprises of tiny, lightweight and energy restricted sensors, placed in/on the human body, to monitor any ambiguity in body organs and measure various biomedical parameters. In this study, a protocol named Distance Aware Relaying Energy-efficient (DARE) to monitor patients in multi-hop Body Area Sensor Networks (BASNs) is proposed. The protocol operates by investigating the ward of a hospital comprising of eight patients, under different topologies by positioning the sink at different locations or making it static or mobile. Seven sensors are attached to each patient, measuring different parameters of Electrocardiogram (ECG), pulse rate, heart rate, temperature level, glucose level, toxins level and motion. To reduce the energy consumption, these sensors communicate with the sink via an on-body relay, affixed on the chest of each patient. The body relay possesses higher energy resources as compared to the body sensors as, they perform aggregation and relaying of data to the sink node. A comparison is also conducted conducted with another protocol of BAN named, Mobility-supporting Adaptive Threshold-based Thermal-aware Energy-efficient Multi-hop ProTocol (M-ATTEMPT). The simulation results show that, the proposed protocol achieves increased network lifetime and efficiently reduces the energy consumption, in relative to M-ATTEMPT protocol.Comment: IEEE 8th International Conference on Broadband and Wireless Computing, Communication and Applications (BWCCA'13), Compiegne, Franc

Charge order suppression and antiferromagnetic to ferromagnetic switch over in Pr_0.5Ca_0.5MnO_3 nanowires

We have prepared crystalline nanowires (diameter ~ 50 nm, length ~ a few microns) of the charge ordering manganite Pr_0.5Ca_0.5Mn_O3 using a low reaction temperature hydrothermal method and characterized them using X-ray diffraction, transmission electron microscopy, SQUID magnetometry and electron magnetic resonance measurements. While the bulk sample shows a charge ordering transition at 245 K and an antiferromagnetic transition at 175 K, SQUID magnetometry and electron magnetic resonance experiments reveal that in the nanowires phase, a ferromagnetic transition occurs at ~ 105 K. Further, the antiferromagnetic transition disappears and the charge ordering transition is suppressed. This result is particularly significant since the charge order in Pr_0.5Ca_0.5MnO_3 is known to be very robust, magnetic fields as high as 27 T being needed to melt it.Comment: 12 pages including 4 figures. submitted to Applied Physics Letter