Sessile Serrated Adenomas in the Proximal Colon are Likely to be Flat, Large and Occur in Smokers

Aim: To examine the epidemiology and the morphology of the proximal sessile serrated adenomas (SSAs). Methods: We conducted a retrospective study to identify patients with SSAs using a university-based hospital pathology database query from January 2007 to April 2011. Data collected included: age, gender, ethnicity, body mass index, diabetes, smoking, family history of colorectal cancer, aspirin, and statin use. We collected data on morphology of SSAs including site (proximal or distal), size, and endoscopic appearance (flat or protuberant). We also compared proximal SSAs to proximal tubular adenomas detected during same time period

Duodenal Bleeding from Metastatic Renal Cell Carcinoma

Massive upper gastrointestinal bleeding due to malignancy is relatively uncommon and the duodenum is the least frequently involved site. Duodenal metastasis is rare in renal cell carcinoma (RCC) and early detection, especially in case of a solitary mass, helps in planning further therapy. We report a case of intractable upper gastrointestinal bleeding from metastatic RCC to the duodenum. The patient presented with melena and anemia, 13 years after nephrectomy for RCC. On esophagogastroduodenoscopy, a submucosal mass was noted in the duodenum, biopsies of which revealed metastatic RCC. In conclusion, metastasis from RCC should be considered in nephrectomized patients presenting with gastrointestinal symptoms and a complete evaluation, especially endoscopic examination followed by biopsy, is suggested

Diabetes prediction using data mining

Diabetes complaint is substantially caused due to increase in blood glucose position. With the growth of Machine knowledge styles, we have got the strictness to search out an answer to the current issue, we have got advanced system mistreatment information processing that has the capability to read whether the case has polygenic illness or not. Like wise, reading the sickness firstly ends up in furnishing the cases before it begins vital. Information retirement has the strictness to remove unseen data from a large volume of diabetes associated information Data wisdom styles are having the capability to gain other scientific fields through rending new light on common questions. One similar task is aiding in making prognostications on medical data is one similar task. Machine literacy is a new scientific field in data wisdom which handles the ways during which machines learn from experience. The design's main end is to introduce a fashion which performs early vaticination of diabetes complaint of a case with better delicacy by combining colorful machine literacy ways' results. The main provocation of doing this design is to present a diabetes vaticination model for the vaticination of circumstance of diabetes

Injectable Amorphous Chitin-Agarose Composite Hydrogels for Biomedical Applications

Injectable hydrogels are gaining popularity as tissue engineering constructs because of their ease of handling and minimal invasive delivery. Making hydrogels from natural polymers helps to overcome biocompatibility issues. Here, we have developed an Amorphous Chitin (ACh)-Agarose (Agr) composite hydrogel using a simpletechnique. Rheological studies, such as viscoelastic behavior (elastic modulus, viscous modulus, yield stress, and consistency), inversion test, and injectability test, were carried out for different ACh-Agr concentrations. The composite gel, having a concentration of 1.5% ACh and 0.25% Agr, showed good elastic modulus (17.3 kPa), yield stress (3.8 kPa), no flow under gravity, injectability, and temperature stability within the physiological range. Based on these studies, the optimum concentration for injectability was found to be 1.5% ACh and 0.25% Agr. This optimized concentration was used for further studies and characterized using FT-IR and SEM. FT-IR studies confirmed the presence of ACh and Agr in the composite gel. SEM results showed that the lyophilized composite gel had good porosity and mesh like networks. The cytocompatibility of the composite gel was studied using human mesenchymal stem cells (hMSCs). The composite gels showed good cell viability.These results indicated that this injectable composite gel can be used for biomedical applications