LONG-TERM EFFECTS OF PYELOPLASTY IN CHILDREN WITH POORLY FUNCTIONING KIDNEYS: A RETROSPECTIVE STUDY.

Background: Pediatric pyeloplasty in ureteropelvic junction obstruction (UPJO) is indicated in renal impaired drainage or renal function deterioration. The improvement of renal function after pediatric pyeloplasty is still controversial in poorly functioning kidneys. Past studies on poorly functioning kidneys had a variable SRF specification, and these studies often had a limited number of patients so that they did not achieve statistical significance. Objective: The objective of this study was to assess the effectiveness and long-term results of pyeloplasty in children with poorly functioning kidneys. Method: Patients who underwent pyeloplasty at Department of Urology, Rajendra Institute of Medical Science, Ranchi for last twelve years were the subject of a retrospective data study. Postoperative outcome was the parameter under study. Success was measured by either symptom improvement or better drainage on postoperative Tc-99m DTPA renography, which was performed after two months and then yearly after that. Results: 60 individuals were enrolled in the study, with a mean age of 8.5 years (3 months to 12 years), a male-to-female ratio of 2:1, and poor function on the isotope renogram (31%). The ratio of left to right sides was 1.2:1. All patients had dismembered pyeloplasty procedures. 37 patients (66.8%) underwent laparoscopic pyeloplasty, whereas 23 (33.2%) underwent open surgery. 35 patients had follow-up renograms available; of these, 30 showed improved drainage and no further decline in renal function, while 5 displayed an obstructed pattern; of these, 3 patients had noticeably worsened split function, and the other two underwent a second open pyeloplasty. A mean follow-up of 21.5 months revealed a 91% overall success rate. Conclusion:  In the pediatric age group, pyeloplasty provides satisfactory intermediate results in kidneys with inadequate function

Ayodhya: The Imageability and Perceptions of Cultural Landscapes

Most of the visitors (pilgrims in the majority) and the dwellers (mostly Hindus) perform some sorts of rituals at varying degrees and become involved in the religious activities to gain solace or soul healing. Of course, as sidetrack visitors also perform other activities of recreation and side-show. However, these are the marginal activities. It is obviously noted that personality of pilgrims and dwellers in the context of economic, social, cultural, job status, and perspective of life, has a direct effect on the nature of environmental sensitivity to its sacred landscapes and mythologies that support and make them alive. Ongoing rituals, continuous performances of Ramalila in the evening, pilgrimages and auspicious glimpses to the divine images, and associated happenings together make the whole are a part of the sacred environment. These are categorised within the frame of responsive perception, testing Kevin Lynch’s scale of imageability represented with the five elements, viz. path, edge, node, district, and landmark. The perceptual survey of dwellers and pilgrims are codified into a composite cognitive map that reflects the generalised images of various behavioural attributes that fit the cultural and natural landscapes of the city; this is similar to other holy cities of north India like Varanasi, Mathura, and Chitrakut

Some Generalizations In Matrix Differentiation With Applications In Multivariate Analysis.

Dept. of Mathematics and Statistics. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1972 .S58. Source: Dissertation Abstracts International, Volume: 33-10, Section: B, page: 5059. Thesis (Ph.D.)--University of Windsor (Canada), 1972

EFFECT OF GIBBERELLIC ACID PRE-TREATMENTS ON GROWTH PARAMETERS OF WALNUT (Juglans regia L.)

Present investigation was carried out during the winter season at Horticulture Research block, Department of Horticulture, Shri Guru Ram Rai University, Dehradun, Uttarakhand. To investigate the effect of GA3 treatment on growth attributes and days taken for germination initiation of walnut. The experiment was laid out in randomized block design with three replications and twelve treatments. The treatments comprised following levels of GA3 concentrations viz. 500ppm, 1000ppm, 15000ppm and control in three different replications of Horticultural Research Block. Various observations regarding growth parameters such as leaf length, leaf width, shoot length, shoot width and numbers of days taken for germination initiation of walnut were recorded. The result revealed that treatment of GA3 1500ppm of nursery polybag application found to be beneficial for vegetative characters viz, found to be the most effective treatment for increasing leaf length, shoot length and shoot diameter. In another point of view, 1500ppm GA3 treatment in polyhouse was found to be profitable as compared to rest of treatments in terms of number of days taken for germination. Apart from this leaf width of 1000ppm in nursery polybag was found best. View Article DOI: 10.47856/ijaast.2021.v08i3.00

Sero-epidemiology of toxoplasmosis and associated risk factors among antenatal women in Ranchi, Jharkhand, India

Background: Toxoplasmosis seroprevalence in antenatal women has remained a contentious issue in Indian subcontinent. Bad obstetric history (BOH) is specific to women of childbearing age and can be caused by infection with Toxoplama gondii. In Jharkhand, scarce data exist for the roles of toxoplasmosis in the aetiology of adverse pregnancy outcome. Aim: To study the sero-epidemiology of Toxoplasmosis and associated risk factors among antenatal women attending antenatal clinic of a tertiary care hospital in Ranchi, Jharkhand, India.Methods: A case-control study was conducted on antenatal women attending antenatal clinic from the June 2010 to May 2011. The study group comprised 102 antenatal women of with BOH while the control group comprised 102 multiparous, age-matched antenatal women without BOH. Latex Slide agglutination test for antibodies to T.gondii was utilized. The research was approved by institutional ethical committee. Descriptive and inferential statistics was applied.Results: The overall seroprevalence of T.gondii among antenatal women was 15.19%, with significantly more in women with BOH (24.50%) as compared to women without BOH (5.88%). The seroprevalence in women with BOH gradually increased with advancing age: 8.33% in age less than 20 years to 50% in women older than 30 years. The seroprevalence increased steadily with number of BOH: 9.67% in women with one BOH to 37.50% in women with three or more BOH. Risk factors like Illiteracy, rural residence, owning a cat and non-veg dietary habit showed significant association.Conclusions: The seroprevalence of toxoplasmosis is high among antenatal women with BOH. Routine serological test is recommended for all pregnant women with BOH

Roots of Withania somnifera Inhibit Forestomach and Skin Carcinogenesis in Mice

We evaluated the cancer chemopreventive efficacy of the Withania somnifera root, which has been used in the Indian traditional medicine system for many centuries for the treatment of various ailments. Since, studies showing its mechanism-based cancer chemopreventive efficacy are limited, this was investigated in the present study. We studied the effect of dietary administration of Withania root on hepatic phase I, phase II and antioxidant enzymes by estimation of its level/activity, as well as in attenuating carcinogen-induced forestomach and skin tumorigenesis in the Swiss albino mouse model. Our findings showed that roots of W.somnifera inhibit phase I, and activates phase II and antioxidant enzymes in the liver. Further, in a long-term tumorigenesis study, Withania inhibited benzo(a)pyrene-induced forestomach papillomagenesis, showing up to 60 and 92% inhibition in tumor incidence and multiplicity, respectively. Similarly, Withania inhibited 7,12-dimethylbenzanthracene-induced skin papillomagenesis, showing up to 45 and 71% inhibition in tumor incidence and multiplicity. In both studies, Withania showed no apparent toxic effects in mice as monitored by the body weight gain profile. Together, these findings suggest that W.somnifera root has chemopreventive efficacy against forestomach and skin carcinogenesis and warrants the identification and isolation of active compounds responsible for its anticancer effects, which may provide the lead for the development of antitumor agents

A Hierarchical Framework of Challenges for Blockchain Adoption in Public Services. Implications for decision-makers

This study attempts to identify critical challenges for blockchain adoption in government, particularly public-service delivery in India, a developing country context. Through an extensive literature review and focus-group discussions with policymakers and blockchain experts, we have identified 12 adoption challenges for Blockchain in public service delivery. We then collected data and analysed using interpretive structural modeling and Cross-Impact Matrix Multiplication Applied to Classification (MICMAC) Analysis to develop a hierarchical framework of the challenges. Our findings indicate that governments must first ensure legislative support for blockchain-based transactions. This research contributes to information systems strategic planning literature and provides a framework for policymakers to craft a strategic approach to facilitate blockchain adoption

Bacteriological Profile and Antibiotic Resistance Pattern of Pathogens Causing Pyogenic Infections At A Tertiary Care Hospital in Central India

Background: Pyogenic infection is a bacterial infection that leads to the formation of pus. Antibiotics are routinely prescribed to treat these pyogenic bacterial infections, but their toxicity poses a severe threat. It is important to know the antimicrobial resistance profile of such pathogens for proper management of the patients. Objectives: To determine the bacteriological profile and antibiotic resistance pattern of pyogens. Patients and Methods: In this cross sectional study, a total of 678 pus samples were received and processed for aerobic culture from various departments. Standard techniques were used to identify isolates from positive pus cultures, and CLSI standards were used to identify antimicrobial susceptibility patterns. Results: Out of the 678 samples, 347 (51.18%) showed growth of pathogenic bacteria. Two hundred seventeen two (40.11%) Gram positive cocci and 75 (11.06%) Gram negative bacilli isolates were identified. Staphylococcus aureus was the most common isolate (57.5%). Most of the isolates were highly resistant to commonly prescribed antimicrobial drugs like Amoxycillin clavulanate. Most of the gram positive isolates were susceptible to vancomycin, linezolid, and teicoplanin. Most of the Gram-negative isolates were sensitive to imipenem. Conclusion: Microbiological profile findings of pus culture isolates as well as their pattern of antimicrobial resistant may aid in the formulation of antibiotic policies for pyogenic infections

Electrophoretic Studies of Biologically Important Mixed Metal – Ascorbic Acid –Nitrilotriacetate Complexes

Quantitative indication of a complex formation comes from the estimation of the stability or formation constants characterizing the equilibria corresponding to the successive addition of ligands. The binary equilibria of metal (II) / (III)–ascorbic acid and also mixed equilibria metal (II) / (III)–ascorbic acid–NTA have been studied using ionophoretic technique. The stability constants of metal–ascorbic acid binary complexes are found to be 103.77, 102.47,102.27 and that of metal–ascorbic acid–NTA mixed complexes have been found to be 106.05, 105.93, 105.75, for Fe(III), Cu(II) and Co(II) complexes, respectively at 25 °C and ionic strength Ic = 0.1 mol dm–3 (HClO4). (doi: 10.5562/cca1778