An environment for studying the impact of spatialising sonified graphs on data comprehension

We describe AudioCave, an environment for exploring the impact of spatialising sonified graphs on a set of numerical data comprehension tasks. Its design builds on findings regarding the effectiveness of sonified graphs for numerical data overview and discovery by visually impaired and blind students. We demonstrate its use as a test bed for comparing the approach of accessing a single sonified numerical datum at a time to one where multiple sonified numerical data can be accessed concurrently. Results from this experiment show that concurrent access facilitates the tackling of our set multivariate data comprehension tasks. AudioCave also demonstrates how the spatialisation of the sonified graphs provides opportunities for sharing the representation. We present two experiments investigating users solving set data comprehension tasks collaboratively by sharing the data representation

A generic approach for augmenting tactile diagrams with spatial non-speech sounds

Blind or visually impaired users typically access diagrams in the tactile medium. This paper describes TouchMelody, a system designed for augmenting such existing diagrams with 3D spatial auditory information to increase their usefulness, information content and reduce tactile clutter. The motivation for this system, an overview of its development and early experiences are presented. The two major technologies used are the Polhemus FASTRAK and the LakeDSP CP4 to facilitate the creation of a directly manipulated dynamic 3D spatial soundscape

Exploring computer-generated line graphs through virtual touch

This paper describes the development and evaluation of a haptic interface designed to provide access to line graphs for blind or visually impaired people. Computer-generated line graphs can be felt by users through the sense of touch produced by a PHANToM force feedback device. Experiments have been conducted to test the effectiveness of this interface with both sighted and blind people. The results show that sighted and blind people have achieved about 89.95% and 86.83% correct answers respectively in the experiment

Design guidelines for audio presentation of graphs and tables

Audio can be used to make visualisations accessible to blind and visually impaired people. The MultiVis Project has carried out research into suitable methods for presenting graphs and tables to blind people through the use of both speech and non-speech audio. This paper presents guidelines extracted from this research. These guidelines will enable designers to implement visualisation systems for blind and visually impaired users, and will provide a framework for researchers wishing to investigate the audio presentation of more complex visualisations

Constructing sonified haptic line graphs for the blind student: first steps

Line graphs stand as an established information visualisation and analysis technique taught at various levels of difficulty according to standard Mathematics curricula. It has been argued that blind individuals cannot use line graphs as a visualisation and analytic tool because they currently primarily exist in the visual medium. The research described in this paper aims at making line graphs accessible to blind students through auditory and haptic media. We describe (1) our design space for representing line graphs, (2) the technology we use to develop our prototypes and (3) the insights from our preliminary work

Technology transfer of antibacterial oral solid dosage form in a pharmaceutical industry

Technology transfer (TT) looks at the transfer of intellectual property from one manufacturing site to another. If carried out successfully, a TT can increase the leveraging capability of the company acquiring the intellectual property together with its brand strength. This in turn aids in a decreased time to market of the final dosage form produced. The aim of the research was to assess the TT of an antibacterial oral solid dosage form from one manufacturing site to another. An expected change of manufacturing equipment from a single-pot to a multi-phase system took place due to the equipment available at the receiving unit. The assessment done by the researcher was performed in the capacity of an observer. The assessment of the TT was performed by observing the critical stages during the transfer process, namely the development and validation stages. Prior to the start of the development stage, a characterisation of innovator was performed. At this stage, innovator batches received from the Sending Unit (SU) were characterised to allow for a means of comparison. The development stage allows for the determination of the robustness of the formulation to be used whilst the validation stage will look at the reproducibility of the chosen formulation. During the development stage, small scale trials were manufactured with amendments made to the original formulation. The amendments allowed for a formulation more comparable to the innovator product with regards to its dissolution profile. The comparable batch produced at a small scale was then up-scaled to a production scale batch and these were compared to the innovator products. The amendments made were on the amount of granulation fluid and binder as well as the method of addition of the disintegrant. When a large scale batch comparable to that of the innovator product was produced, the validation stage was started. With the aim of showing reproducibility of the Receiving Unit (RU) at producing large scale batches, three batches were produced. These were tested for all critical parameters, namely through the loss on drying, particle size distribution, hardness, disintegration and dissolution tests and, the results of the tests were compared to the specifications set by the SU. They were also compared to each other, enabling statistical determination of any significant difference across the batches through the use of comparative statistical analyses. Comparison of batches, at the development and validation stage, was done using the dissolution potential of the batches. These were performed through the use of statistical analyses. The RU made use of the similarity factor (F2) to compare the dissolution profiles. For the purpose of this research, the 1-Way analysis of variance was also used, which compared to the similarity factor, took in consideration the level of variance of the batches produced. Results and discussion: During the development stage amendments were made to produce a batch comparable to the innovator product. The amendments that led to the production of a comparable batch consisted of an extra 14 % of granulation fluid as well as 50 % of the disintegrant being added intra-granularly with the other 50 % added extra-granularly. The amendments were added on top of the amount suggested by the SU. This formulation was used and three batches produced consecutively. On comparison to the specifications set by the SU, the three batches were seen to be within the specifications. On comparison to each other, the dissolution profiles were seen to be different. Conclusion and recommendation: The development stage producing batches within the specifications set by the SU but also comparable with regards to its dissolution profile, was seen to be successful. The validation stage was seen to be unsuccessful. Even though the results of the critical parameters were within specifications, when compared to each other, the batches were seen to be significantly different. This led to the research looking at the TT as a whole as being unsuccessful. The researcher then determined what stage could be improved and how this could be done. The various stages seen as having associated problems were determined and ways to mitigate those were determined. A guideline in the form of a flow chart was proposed to aid a manufacturing facility undertaking a TT to shorten the period of time to completion as well as increase the chance of success

Web 3D for Public, Environmental and Occupational Health: Early Examples from Second Life®

Over the past three years (2006-2008), the medical/health and public health communities have shown a growing interest in using online 3D virtual worlds like Second Life® (http://secondlife.com/) for health education, community outreach, training and simulations purposes. 3D virtual worlds are seen as the precursors of ‘Web 3D’, the next major iteration of the Internet that will follow in the coming years. This paper provides a tour of several flagship Web 3D experiences in Second Life®, including Play2Train Islands (emergency preparedness training), the US Centers for Disease Control and Prevention—CDC Island (public health), Karuna Island (AIDS support and information), Tox Town at Virtual NLM Island (US National Library of Medicine - environmental health), and Jefferson’s Occupational Therapy Center. We also discuss the potential and future of Web 3D. These are still early days of 3D virtual worlds, and there are still many more untapped potentials and affordances of 3D virtual worlds that are yet to be explored, as the technology matures further and improves over the coming months and years

Web-based multimodal graphs for visually impaired people

This paper describes the development and evaluation of Web-based multimodal graphs designed for visually impaired and blind people. The information in the graphs is conveyed to visually impaired people through haptic and audio channels. The motivation of this work is to address problems faced by visually impaired people in accessing graphical information on the Internet, particularly the common types of graphs for data visualization. In our work, line graphs, bar charts and pie charts are accessible through a force feedback device, the Logitech WingMan Force Feedback Mouse. Pre-recorded sound files are used to represent graph contents to users. In order to test the usability of the developed Web graphs, an evaluation was conducted with bar charts as the experimental platform. The results showed that the participants could successfully use the haptic and audio features to extract information from the Web graphs

Design guidelines for audio representation of graphs and tables

Proceedings of the 9th International Conference on Auditory Display (ICAD), Boston, MA, July 7-9, 2003.Audio can be used to make visualisations accessible to blind and visually impaired people. The MultiVis Project has carried out research into suitable methods for presenting graphs and tables to blind people through the use of both speech and non-speech audio. This paper presents guidelines extracted from this research. These guidelines will enable designers to implement visualisation systems for blind and visually impaired users, and will provide a framework for researchers wishing to investigate the audio presentation of more complex visualisations

Web 3D for Public, Environmental and Occupational Health: Early Examples from Second Life®

Over the past three years (2006–2008), the medical/health and public health communities have shown a growing interest in using online 3D virtual worlds like Second Life® (http://secondlife.com/) for health education, community outreach, training and simulations purposes. 3D virtual worlds are seen as the precursors of ‘Web 3D’, the next major iteration of the Internet that will follow in the coming years. This paper provides a tour of several flagship Web 3D experiences in Second Life®, including Play2Train Islands (emergency preparedness training), the US Centers for Disease Control and Prevention—CDC Island (public health), Karuna Island (AIDS support and information), Tox Town at Virtual NLM Island (US National Library of Medicine - environmental health), and Jefferson’s Occupational Therapy Center. We also discuss the potential and future of Web 3D. These are still early days of 3D virtual worlds, and there are still many more untapped potentials and affordances of 3D virtual worlds that are yet to be explored, as the technology matures further and improves over the coming months and years