Design and development of an innovative and simple optical sensor for the detection of acetic acid

The technology we are developing consists of the use of coordination compounds with metals to carry out this detection of Acetic acid. This compound normally reacts with acetic acid changing its colour, making it a suitable compound for use as a detector. The proposed method allows detecting acetic acid in any medium, whether in solution, in the gas phase, in the solid phase, or in any combination of these. Upon contact with the acid, a colour change occurs that can be detected visually or through optical means. After its use, the active medium can be regenerated by a simple procedure and be available again for new use. This allows the creation of simple and intuitive detection devices, usable by non-experts and that can be regenerated and reused. The main advantage of this sensor is to allow the specific detection of acetic acid and quantification of its concentration, using coordination compounds with metals that are present in the yellow dye.This work was supported by Ministerio de Ciencia e Innovación (Spain) under project PID2019-106601RB I00,and Generalitat Valenciana (Spain) under projects IDIFEDER/2021/014 (cofunded by European Union through the FEDER Programme), PROMETEO2021/006

Design and development of a simple and innovative Optical detection sensor for acetic acid

The technology we are developing consists of the use of coordination compounds with metals to carry out the detection of acetic acid, which is a harmful substance for human health and some art works.This work was supported by Ministerio de Ciencia e Innovación (Spain) under project PID2019-106601RB-I00, and Generalitat Valenciana (Spain) under projects IDIFEDER/2021/014 (cofunded by European Union through the FEDER Programme), PROMETEO 2021/006

Costs Analysis of Fibrin Sealant for Prevention of Anastomotic Leakage in Lower Colorectal Surgery

Introduction: Postoperative anastomotic leaks remain a common and serious complication of colorectal surgeries and are a major cause of mortality and morbidity of these procedures. Anastomotic leaks (AL) have been extensively studied; however, there has been no significant reduction in their prevalence over time. In addition, there is a significant economic burden from AL attributed to the need for repeat surgery, radiologic intervention and lengthened hospital stay. We conducted a comparative cost analysis of patients undergoing colorectal surgery with anastomosis, with the application of fibrin sealant (FS) to the sutured anastomosis versus not treating the sutured anastomosis with FS. Methods: The deterministic decision-tree model was populated with clinical data including operating room time, hospitalization days, occurrence of AL, need for revision surgery, blood products and radiologic interventions to treat the AL in lower colorectal surgery. A systematic literature review was conducted to identify appropriate studies with these variables. Results: The average cost per case treated lower colorectal surgery with fibrin sealant glue 10 mL Tisseel® and those not treated with a fibrin sealant after suturing the anastomoses was €3233 and €4130, respectively, for resource expenses paid by the healthcare system. This would suggest potential savings of €897 per surgery, achieved through the application of FS to the sutured anastomosis for preventing AL following colorectal surgery. Conclusion: Application of FS to the sutured anastomosis in lower colorectal surgery resulted in a decrease in post-operative AL, and cost savings based on a reduction in hospitalization days, a reduction needing: revision surgery, radiologic intervention and blood products to treat AL

Time-stable holograms stored in hydrogel matrix

Storing holograms in hydrogel matrices and its temporal stability is real challenge when the material is immersed in aqueous medium. Hydrogels are 3D polymer networks capable of undergoing reversible volume changes. Since they can be synthesized to be sensitive to a range of relevant analytes, one of the most important applications of this type of system are holographic sensors. These sensors have great potential to be used in different areas such as environmental detection, veterinary testing, pharmaceutical bioassays, and medical diagnosis. Therefore, a key factor in the manufacture of holographic sensors is to develop and optimize hydrogel matrices in which stable holograms can be stored over time and in aqueous media where analytes are present.Thanks to the government of Algeria for the scholarship offered to develop my thesis in the Holography and Optical Processing Group of the University of Alicante, to the Spanish Ministerio de Ciencia e Innovación under project PID2019-106601RB-I00, to Generalitat Valenciana (Spain) CDIAGENT/2018/024, to IDIFEDER/2021/014 (potencial FEDER funding

Distributed feedback lasers based on dichromated poly(vinyl alcohol) reusable surface-relief gratings

A simple, low-cost and versatile holographic method to produce reusable surface-relief gratings on dichromated poly(vinyl alcohol) (DCPVA) films, with periods Λ ≥ 270 nm and modulation depths up to 300 nm, is reported. DCPVA presents processing advantages with respect to other photoresists, such as dichromated gelatine, i.e. higher light sensitivity, simpler fabrication process and better batch to batch reproducibility. The successful use of these DCPVA relief gratings as distributed feedback (DFB) laser resonators is demonstrated. Second-order DFB devices emitting in the wavelength range 577-614 nm have been easily prepared by coating a dye-doped polymer film on top of the resonators.We thank the Spanish Government (MINECO) and the European Union (FEDER) for grant no. MAT2011-28167-C02

Holographic Lens Resolution Using the Convolution Theorem

The similarity between object and image of negative asymmetrical holographic lenses (HLs) stored in a low-toxicity photopolymer has been evaluated theoretically and experimentally. Asymmetrical experimental setups with negative focal lengths have been used to obtain HLs. For this purpose, the resolution of the HLs was calculated using the convolution theorem. A USAF 1951 test was used as an object and the impulse responses of the HLs, which in this case was the amplitude spread function (ASF), were obtained with two different methods: using a CCD sensor and a Hartmann Shack (HS) wavefront sensor. For a negative asymmetrically recorded HL a maximum resolution of 11.31 lp/mm was obtained. It was evaluated at 473 nm wavelength. A theoretical study of object-image similarity had carried out using the MSE (mean squared error) metric to evaluate the experimental results obtained quantitatively.This research was funded by Universidad de Alicante (UAFPU20-23); Generalitat Valenciana (CIDEXG/2022/60, CDEIGENT/2018/024, IDIFEDER/2021/014, PROMETEO/2021/006); Ministerio de Ciencia e Innovación (PID2019-106601RB-I00, PID2021-123124OB-I00)

Holographic solar concentrators stored in an eco-friendly photopolymer

In this work it is shown the first characterization of holographic solar concentrators recorded in Biophotopol - one of the greenest photopolymers. Biophotopol is an acrylate-based and water-soluble photopolymer with good recycling properties. The composition of this photopolymer and their thickness are easily changeable, which implies an important advantage vs. others commercialized photopolymers. Good diffraction efficiency and wide acceptance angles are achieved on phase volume transmission holograms by using an optimized composition and thin layers. A curing stage with a white incoherent light has been performed to obtain high temporal stability together with a good diffraction efficiency. Finally, the performance of the holographic lenses as holographic solar concentrators has been evaluated with an electronic setup connected to a polycrystalline silicon photovoltaic cell and a high intensity solar simulator emitting a standard solar spectrum (AM1.5G).This work has financial support from: Ministerio de Ciencia e Innovación, Spain, under project PID2019-106601RB-I00 and FIS2017-82919-R/(MINECO/AE/FEDER, UE); Generalitat Valenciana, Spain, under project CDEIGENT/2018/024

Perylenediimide-based distributed feedback lasers with holographic relief gratings on dichromated gelatine

One dimensional second-order distributed feedback (DFB) lasers consisting of polystyrene (PS) films doped with a perylenediimide laser dye, deposited over dichromated gelatine (DCG) photoresist layers with solvent resistant relief gratings recorded by holographic lithography, are reported. The advantage of using the grating on DCG in the final device is that the fabrication process is simplified and the grating pattern better preserved, since no etching methods to transfer the grating to another substrate are needed. A very simple model, proposed to explain the experimental waveguide properties, has allowed identifying the waveguide mode at which DFB emission appears, which was the key to optimize the device performance. In the frame of this model, the thickness of the PS and DCG films could be adjusted in order to minimize the laser threshold and to control its wavelength tuneability. The performance of these lasers is comparable to that of recently reported devices based on the same active material, but deposited over high-quality DFB gratings engraved on SiO2 by nanoimprint lithography.We thank support from the Spanish Government (MINECO) and the European Community (FEDER) through Grant Nos. MAT2008-06648-C02 and MAT-2011-28167-C02, as well as to the University of Alicante. M.G.R. was supported by a CSIC fellowship within the program JAE

Quality and measurement aberrations on holographic lenses

Abstract: In this paper, we have evaluated the quality of holographic lenses stored in an environmentally friendly photopolymer. Optical quality metrics has been used to test the holographic lenses. The metrics values obtained shows that the negative asymmetrical holographic lenses have the best optical quality.Work funded by Ministerio de Ciencia, Innovación y Universidades, Spain, under project PID2019-106601RB-I00; Generalitat Valenciana, Spain, under projects CDEI-GENT/2018/024, PROMETEO/2021/006, and IDIFEDER/2021/014 (co-funded by European Union through the FEDER Programme); Universidad de Alicante, Spain: Predoctoral Fellowship FPU-UA to Tomás Lloret