Ist das Privileg Calixts II aus dem Jahre 1123 für Marchiennes original ?

Ramackers Johannes. Ist das Privileg Calixts II aus dem Jahre 1123 für Marchiennes original ?. In: Revue belge de philologie et d'histoire, tome 16, fasc. 1-2, 1937. pp. 183-189

La dalle funéraire du Pape Adrien Ier et l'atelier de fabrication

Ramackers Johannes. La dalle funéraire du Pape Adrien Ier et l'atelier de fabrication . In: Revue du Nord, tome 46, n°180, Janvier-mars 1964. pp. 78-82

Impact of Salinomycin-treatment on PHH synthesis function.

<p>Functionality of PHH after treatment with Salinomycin was analyzed by urea formation and albumin synthesis. (<b>A</b>) 24 hours of Salinomycin exposure at varying concentrations was not accompanied by impaired urea formation at all. (<b>B</b>) In contrast, treatment for 48 hours resulted in a dose-dependent decrease of urea formation at days 1, 3 and 5 without reaching statistical significance. (<b>C+D</b>) Albumin synthesis was markedly impaired at day 1 after stimulation with Salinomycin for 24 and 48 hours, respectively. Further incubation led to continuous recovery of albumin synthesis in the groups with 24 hours of drug exposure. In contrast, treatment for 48 hours resulted only in moderate recovery of albumin synthesis (n = 3). * p<0.05, ** p<0.005.</p

Salinomycin impairs HCC cell survival.

<p>HepG2 and Huh7 cells were exposed to increasing concentrations of Salinomycin (1, 2, 5 and 10 µM) for 24 hours. (<b>A</b>) Cell viability was assessed by MTS-assay; high concentrations of Salinomycin led to significantly decreased viability of both cell lines (n = 5). (<b>B</b>) HCC cells revealed significantly reduced proliferation after exposure to Salinomycin as demonstrated by decreased ³H-Thymidine uptake. (<b>C</b>) Low concentrations of Salinomycin (left panel, solid line) led to weak increase of apoptotic cells compared to untreated cells (dotted line in overlay). High concentrations markedly induced apoptosis (right panel, solid line). Results are shown as representative scatter-grams of Annexin-V⁺-cells or summarized as mean ± SD of n = 4 independent experiments (<b>D</b>). *p<0.05, **p<0.01.</p