Antimicrobial prescribing pattern in a tertiary care teaching hospital: a pilot study

Background: The emergence of antimicrobial resistance is a worldwide challenge threatening to negate the gains made by discovery of antimicrobial agents (AMAs).  Antimicrobial Stewardship Program (ASP) is an important strategy for ensuring appropriate use of AMAs and controlling emergence of antibiotic resistance. Implementation of ASP must start with assessment of the current state of antimicrobial use. This study was therefore conducted to assess the prevalent prescribing patterns in a tertiary care hospital and identify gaps which warrant corrective intervention.Methods: This prospective pilot study presents analysis of the first 30 Patients from the medicine ward prescribed at least one antimicrobial agent during the two months of study period. Relevant data was collected in AMA record form. Appropriateness of AMAs was analyzed regarding selection as well as administration protocol as per the hospital antibiotic policy.Results: Out of the 60 AMAs prescribed to these patients, most commonly prescribed were cephalosporins (63.3%), anti-amoebics (26.6%) and macrolides (23.3%). Common diseases involved were urinary tract infection, acute gastroenteritis, sepsis and lower respiratory tract infections.  Use of AMAs was found to be appropriate for the indication in 42 %, dose in 97%, duration 60 %, route 93% and frequency 90 %.Conclusions: This gap between the appropriate and the actual practice use of AMAs indicates an urgent need of rigorous implementation of ASP in order to avoid emergence of resistance and to conserve the sensitivity to the available AMAs

“Evaluation Of Efficacy Of Homeopathic Medicine Silicea Terra In Subcutaneous Abscess In Experimental Animals”

Abscess is a common skin problem in all human beings however the standard treatment involves drainage of pus and use of antibiotics which may be painful. There is a need to develop an alternative therapy like Homoeopathy. Homoeopathic medicines are broadly used for various skin diseases involved with pus formation with gentle and permanent results; however, their preclinical assessment remains a key challenge. Objectives: This study aimed to see the efficacy of homeopathic medicine Silicea terra in subcutaneous abscess in experimental animals. Hypothesis: We hypothesize that all potencies of homoeopathic medicine Silicea terra shows efficacy in treating subcutaneous abscess in mice. Methods: Homoeopathic medicine Silicea terra was used in different liquid potencies (12CH, 30CH, 200CH ) against subcutaneous abscess in mice and the results were observed against standard antibiotic amoxicillin. Results: Homoeopathic medicine Silicea terra in different liquid potencies (12CH, 30CH, 200CH ) were used and it was observed that it has an antibacterial effect and also positive effect on subcutaneous abscess size, therefore it can be used in treatment of subcutaneous abscess Conclusions: The present study reveals that Homoeopathic Medicine Silicea terra could be an effective drug in treating subcutaneous abscess