4 research outputs found

    Davis oxaziridine-mediated asymmetric synthesis of proton pump inhibitors using DBU salt of prochiral sulfide

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    A simple and clean asymmetric synthesis of proton pump inhibitors using inexpensive 10-camphorsulfonyl oxaziridine is described. Here, we report the activation of prochiral sulfide by making the DBU salt that is capable of enhancing the reactivity and enantioselectivity

    Corey–Itsuno Reduction of Ketones: A Development of Safe and Inexpensive Process for Synthesis of Some API Intermediates

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    A safe and inexpensive procedure for asymmetric reduction of ketones using in situ prepared <i>N</i>,<i>N</i>-diethylaniline borane (DEANB) and oxazaborolidine catalyst from sodium borohydride, <i>N</i>,<i>N</i>-diethylaniline hydrochloride and (<i>S</i>)-α,α-diphenylprolinol is described. This protocol is demonstrated successfully to manufacture enantiopure dapoxetine at the plant scale

    Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020

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    This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India. Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-
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