AN INTRODUCTORY APPROACH TO PAIN MANAGEMENT THROUGH AYURVEDA WITH BRIEF HOLISTIC REVIEW

The whole world is fighting with pain whatever may be its source or origin. Pain is a protective body mechanism, which alerts the person about the harmful condition or experience that occurs in the body .In Ayurveda, Vata Dosha is the root cause of all types of pain (Shoola) - “Vatat rute Nasti Ruja” as mentioned by Acharya Sushruta. The concept of pain in Ayurveda is based on the fundamental theories of Tridoshas, Triguna, Srotas and Ojas, but it has also certain relations with the Karma of previous birth as depicted by Maharishi Charaka as “Karmaja Roga” . The Ayurvedic texts describes a wide range of pain; Shoola (piercing pain), being most prominent form, Dank (bursting), Vedana (unbearable sensation), Dagdha (burning pain), Chosa (sucking pain), Nirmathan (churning like), Shastraviddh (cutting like), Spandana (vibration) are some of other expressions. Associated Doshas with the Vata can alter the type and intensity of the pain as dull aching and from sharp neuralgic pain to burning pain in Kapha and Pitta associated Vata Dosha respectively. The hindrance in Vata Dosha flow leads to the pain. In modern medicine, Pain is the most common symptoms of inflammatory process, like wise use of NSAIDs is associated  with risk of fatal gastrointestinal bleeding, increase  in stomach acid, reduce the stomach normal protective mucus layer, cause damage to the kidneys in people over 60; those with high blood pressure, heart disease, or pre-existing kidney diseases. All Ayurvedic treatments and therapies involve bio purification of body channels as well as immune stabilization and management of psyche, strengthen and enhance the body own healing process and donot have adverse effects, if given in proper dose according to the fundamental principles of Ayurveda

MODE OF ACTION OF AMRITADYA GUGGULU IN THE MANAGEMENT OF STHOULYA W.S.R TO OBESITY

Obesity (Sthoulya) is the major and basic cause of lifestyle disorders like Diabetes mellitus (T2DM), Coronary heart disease (CHD), Hypertension. Obesity (Sthaulya) is increasing at an alarming rate in developed industrialized countries which are undergoing rapid nutrition and lifestyle transition. Obesity is one of the most effective diseases which affect someone’s social, physical and mental status. In Ayurveda, Sthoulya (Obesity) is regarded as Medoroga, a disorder of Meda Dhatu, which includes fat tissue and fat metabolism. According to Ayurveda, Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as excess weight. Overweight and obesity are linked to more deaths worldwide than underweight. Overall, about 13% of the world adult population (11% of men and 15% of women) was obese in 2016. The worldwide prevalence of obesity nearly tripled between 1975 and 2016. Amritadya Guggulu possesses Rasa- Katu, Tikta, Kashaya, Guna- Laghu, Ruksha and Virya- Ushna, Vipaka- Katu, Dosha Karma- Kapha Vatashamaka is effective in the management of Sthoulya. By virtue of its Rasapanchaka, contents of drug are very well indicated in Kapha predominant pathologies. Due to this property, it breaks the Samprapti of Sthoulya. Hence the present attempt is done to encompass the up to date comprehensive literature to study the mode of action of Amritadya Guggulu in the management of Sthoulya w.s.r. to Ayurvedic properties and modern pharmacology

ROLE OF AHARA AS A PRIME ETIOLOGICAL FACTOR IN THE MANIFESTATION OF DISEASE

Ayurveda considers Ahara (food) as one of the three supporting pillars. Food has been given prime importance since Vedic Period. It is considered as Brahma in Upanishad. Acharaya Kashyapa gives it the name Mahabhaisajya. This is responsible for the growth, development and enhancement of Ojas. The body as well as diseases; both psychological and lifestyle disorders like Heart disease, Obesity, Diabetes, Hypertension and Cancer being the major health problems are formed by food, wholesome and unwholesome food are responsible for happiness and misery respectively. The disease can be cured without any medication by just following wholesome regimen, whereas even hundreds of medicines cannot be cure a disease in absence of wholesome regimen. Ahara rasa which is formed from ingested diet nourished not only our body but also nourished mind and sensory organs. Ayurveda describes that Deha is made up of Ahara and the Vyadhi also. According to Laulimbaraja Pathya is the secret of healthiness likewise Apathya is the root cause of all diseases. Ayurvedic Acharayas describes importance of Ahara differently especially in Brihatrayee, a special chapter has been described for Annapana Vidhi. The principle of dietetics and nutrition in Ayurvedic system of medicine include different classes of Ahara i.e. eating and drinking items, principle of Pathyapathya (wholesome and unwholesome diet), discipline of eating (Ashta Ahara Vidhi Visheshayatan, Dvadasha Asana Vidhi etc.), Viruddha Ahara (incompatible diet). Ashta Ahara Vidhi Visheshayatan includes eight discipline of eating and Dvadasha Asana Vidhi includes the twelve discipline of eating as described by Acharya Charaka and Sushruta respectively and is very important in daily life for promotion of positive health

ROLE OF DIET AND LIFESTYLE IN THE PREVENTION OF MADHUMEHA

Ayurveda is a natural health care system that originated in India since the beginning of civilization. It is described by Acharaya Charak that to achieve Purushartha Chatushtaya, Arogya is necessary. Ayurveda strongly emphasize on preventive and promotive aspects of health rather than curative. The concepts of Dincharya, Ritucharya, Sadvritta, and Achara Rasayana along with guidelines for healthy diet and lifestyle is well established in Ayurveda, but in current scenario, hardly anyone aptly follow it. As a result, there is tremendous rise in lifestyle disorders as pandemics, Diabetes being most menacing among them. Diabetes is the fourth leading cause of global death by disease. Type 2 DM is responsible for approximately 90% of cases. In Ayurveda, Madhumeha one of the types of Vataja Prameha is compared to Diabetes Mellitus because of having similarities of disease in respect to etiopathogenesis, clinical features and prognosis. The main causes of Madhumeha are lack of exercise, improper food habits, excessive intake of food having Snigdha and Guru Guna and food which causes vitiation of Kapha Dosha. Modern therapeutics has many limitations but Ayurvedic principles of management can help the patient to control blood glucose level and have better routine life. So Ayurvedic lifestyle guidelines of adopting a healthy dietary pattern together with physical activity are valuable tools in the prevention of Madhumeha

A Clinical and Laboratory Profile of Sthaulya W.S.R to Obesity and its Management by Amritadya Guggulu

In Ayurveda, it is regarded as Medoroga which includes fat tissue and fat metabolism, results from the excessive accumulation of Meda (fat/ adipose tissue) and Mamsa (flesh/ muscle tissue) leading to flabbiness of hips, abdomen, and breast. It is considered as Santarpanottha Vikara and counted one among the Ashtnindita Purusha by Ayurvedic Acharayas. According to Ayurveda, Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as Sthoulya. It is most prevailing condition being faced by majority of the population, but yet among the most neglected health problem in the world. In this regard approach of this study is to give safer, comprehensive and rational option for treating Sthaulya (Obesity) and this is a humble attempt to probe into the different pathophysiological aspects behind Sthaulya, taking into consideration the classical therapy coupled with modern interpretations. Amritadya Guggulu by the virtue of its Rasapanchaka (Rasa- Katu, Tikta, Kashaya, Guna- Laghu, Ruksha and Virya- Ushna, Vipaka- Katu, Dosha Karma- Kapha Vatashamaka) is effective in the management of Sthoulya including all Kapha predominant pathologies, leading to Samprapti Vigatana of Sthoulya. Hence this study is carried out to establish the efficacy of the treatment considering the clinical and laboratory profile of obesity (Sthoulya). The study was done on 30 patients taken from both IPD & OPD of RGGPG Ayurvedic College and Hospital, Paprola, H.P. The duration of the trial was 60 days with follow up of 15 days and the observations obtained are analyzed statistically after the end of the study

Effect of foot-and-mouth disease vaccination on acute phase response and milk production in the Holstein-Friesian crossbred cow

AbstractThe study investigated the effects of FMD vaccination on acute phase response and milk composition in the HF crossbred cows (n = 12) using a cross-over experimental design. In trial 1, one group (n = 6) received inactivated trivalent oil-adjuvanted FMD vaccine [day post-vaccination, (dpv) 0], while the mock-vaccinated group received saline (n = 6). After a cooling period of 15 days, the trial was repeated by swapping groups. The body temperature, dry matter intake (DMI) and milk yield were recorded. Haemato-biochemical parameters, haptoglobin and cortisol concentrations were also assessed. A significant (p < 0.05) increase in the neutralizing antibody response to FMDV serotype O and Asia1 indicated a positive immune response. A significant (p < 0.05) increase of 0.4° to 0.6°C in the body temperature, decrease of 0.7–0.8 kg in DMI along with an increase in the serum haptoglobin, total leukocyte count and neutrophils within dpv 2 indicated acute phase response in the FMD vaccinated group. Among the milk constituents, only milk fat (p = 0.053) was significant. It was concluded that FMD vaccination induced acute phase response within dpv 3 in the crossbred cows and caused a non-significant reduction in the milk yield on the day of vaccination