294 research outputs found
Quantum simulations of attosecond physics
We develop a numerical simulator to solve the time-dependent Schrödinger equation (TDSE) to simulate strong field ionization of a single electron under the influence of a one-dimensional separable potential. We use the split-step method to solve TDSE, obtain the ground state using the imaginary time method and benchmark it with the exact diagonalization of Hamiltonian. We perform the stability analysis in both real-time and imaginary-time propagation and obtain the fact that the usual model of separable orbital is not suitable in this method and demonstrate how a Gaussian model can solve this issue. Finally, we perform a comparative analysis between the analytical ground state and an adapted version of ground state adjusted according to the time-step of TDSE to justify the origin of the numerical error
Clinical Studies on Reversibility of Pulmonary Airway Dysfunctions in Asymptomatic Smokers: Role of Nervous Mechanism in Small Airway Disease
Pulmonary function tests were performed on twenty eight males, among whom eight were healthy nonsmokers and twenty were asymptomatic smokers. Pulmonary function tests such as spirometry, respiratory impedance (Z3Hz), single breath nitrogen washout (SBN2) and volume of isoflow (VisoV) were done before and after inhalation of orciprenaline sulphate and atropine sulphate in all nonsmokers and smokers. Subdivisions of lung volume, diffusing capacity (DLco) and arterial blood gas analysis were conducted only before inhalation of drugs. Acute effects were studied after smoking a cigarette and effects of orciprenaline inhalation after smoking were also observed. Furthermore, effects of smoking on prior inhalation of orciprenaline, atropine or lidocaine were evaluated.
The results obtained were as follows:
1) There were no differences in the results of routine pulmonary function tests, between nonsmokers and smokers except Z3Hz, which was significantly higher in smokers (p<0.01) and there was a tendency to decrease in flow especially at low lung volumes in smokers. Smokers could be well differentiated from nonsmokers by VisoV/FVC (p<0.001) and the difference in distribution of ventilation was greater (p<0.05).
2) In nonsmokers, Z3Hz decreased and V50 increased significantly after inhalation of orciprenaline and atropine. FEV1.o increased significantly with atropine inhalation only. There were no changes in VisoV/FVC with inhalation of orciprenaline or atropine.
In smokers, Z3Hz and VisoV/FVC decreased significantly after inhalation of orciprenaline or atropine (p<0.001). FEV1.o and flow rates improved significantly with both drugs.
3) After smoking a cigarette, Z3Hz and VisoV/FVC significantly increased (p < 0.01), but inhalation of orciprenaline or atropine prior to smoking significantly inhibited the acute effects of smoking and lidocaine completely inhibited the acute effects of smoking.
These results indicate that several parameters such as Z3Hz, flow at low lung volume, VisoV/FVC could detect the airway dysfunctions in asymptomatic cigarette smokers. These airway dysfunctions might be due to increased vagal tone, leading to narrowing of the airways and these airway dysfunctions were reversible by bronchodilator drugs.This study was performed in the Second Department of Internal Medicine, Hiroshima University School of Medicine, under a scholarship granted by The Ministry of Education, Science and Culture (Monbusho), The Government of Japan
Poster: Improving Bug Localization with Report Quality Dynamics and Query Reformulation
Recent findings from a user study suggest that IR-based bug localization
techniques do not perform well if the bug report lacks rich structured
information such as relevant program entity names. On the contrary, excessive
structured information such as stack traces in the bug report might always not
be helpful for the automated bug localization. In this paper, we conduct a
large empirical study using 5,500 bug reports from eight subject systems and
replicating three existing studies from the literature. Our findings (1)
empirically demonstrate how quality dynamics of bug reports affect the
performances of IR-based bug localization, and (2) suggest potential ways
(e.g., query reformulations) to overcome such limitations.Comment: The 40th International Conference on Software Engineering (Companion
volume, Poster Track) (ICSE 2018), pp. 348--349, Gothenburg, Sweden, May,
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