Electronic Appraisal Methodology for Right-of-Way Acquisition in Highway Projects

When right-of-way is acquired for highway projects, state departments of transportation (DOTs) must ensure property owners receive a fair market value for their land by delivering high-quality appraisals. Despite recent technological advances, the highly complicated appraisal process often results in similar properties being assessed differently. Several DOTs sponsored a study to develop an electronic appraisal method to improve the appraisal process and to reduce the likelihood of inconsistent appraisal values by capturing, transmitting, storing, managing, and analyzing the appraisal data. The proposed method’s framework is discussed and a prototype of the system has been developed to demonstrate its features

Development of Best Practices for Right-of-Way Valuations and Negotiations in Transportation Projects

The valuations of properties and the negotiations with property owners are two major tasks in the right-of-way acquisition process for transportation projects. If improved, those tasks can increase the overall project delivery efficiency. The Texas Department of Transportation (TxDOT) funded a research project that aimed to recommend some best practices for successful valuations and negotiations in Texas. The authors reviewed the different strategies and procedures followed in TxDOT by conducting interviews and surveys with right-of-way personnel. Guidelines supported by recommended practices were identified for both valuation and negotiation and then reviewed and validated by experts. Lastly, implementation guides were developed

The accuracy of ADC measurements in liver is improved by a tailored and computationally efficient local-rigid registration algorithm

This study describes post-processing methodologies to reduce the effects of physiological motion in measurements of apparent diffusion coefficient (ADC) in the liver. The aims of the study are to improve the accuracy of ADC measurements in liver disease to support quantitative clinical characterisation and reduce the number of patients required for sequential studies of disease progression and therapeutic effects. Two motion correction methods are compared, one based on non-rigid registration (NRA) using freely available open source algorithms and the other a local-rigid registration (LRA) specifically designed for use with diffusion weighted magnetic resonance (DW-MR) data. Performance of these methods is evaluated using metrics computed from regional ADC histograms on abdominal image slices from healthy volunteers. While the non-rigid registration method has the advantages of being applicable on the whole volume and in a fully automatic fashion, the local-rigid registration method is faster while maintaining the integrity of the biological structures essential for analysis of tissue heterogeneity. Our findings also indicate that the averaging commonly applied to DW-MR images as part of the acquisition protocol should be avoided if possible

IL-2 Regulates Expression of C-MAF in Human CD4 T Cells

Blockade of IL-2R with humanized anti-CD25 Abs, such as daclizumab, inhibits Th2 responses in human T cells. Recent murine studies have shown that IL-2 also plays a significant role in regulating Th2 cell differentiation by activated STAT5. To explore the role of activated STAT5 in the Th2 differentiation of primary human T cells, we studied the mechanisms underlying IL-2 regulation of C-MAF expression. Chromatin immunoprecipitation studies revealed that IL-2 induced STAT5 binding to specific sites in the C-MAF promoter. These sites corresponded to regions enriched for markers of chromatin architectural features in both resting CD4 and differentiated Th2 cells. Unlike IL-6, IL-2 induced C-MAF expression in CD4 T cells with or without prior TCR stimulation. TCR-induced C-MAF expression was significantly inhibited by treatment with daclizumab or a JAK3 inhibitor, R333. Furthermore, IL-2 and IL-6 synergistically induced C-MAF expression in TCR-activated T cells, suggesting functional cooperation between these cytokines. Finally, both TCR-induced early IL4 mRNA expression and IL-4 cytokine expression in differentiated Th2 cells were significantly inhibited by IL-2R blockade. Thus, our findings demonstrate the importance of IL-2 in Th2 differentiation in human T cells and support the notion that IL-2R–directed therapies may have utility in the treatment of allergic disorders

Correlation and regression analysis in sorghum under different levels of nitrogen

An experiment was conducted with sorghum varieties and different levels of nitrogen to study the correlation between traits and to study the effect of these traits on grain yield to define which traits can be considered as selection criteria for yield improvement in sorghum. A factorial irrigated field experiment was carried out in R.C.B.D. layout with three replications in Iraq, four sorghum varieties (AlKhir, Enkath, Kafir, and Rabeh) were planted under three levels of nitrogen (80,100,120) kg/h manually in 2016 at two sites. After harvest, correlation and regression analysis were studied between grain yield as the dependent variable and each of the following traits as independent variables (dry and green fodder weight, leaf area index, plant height, stem diameter, grain number and grain weight, nitrogen level). Results showed that all studied traits except grain weight were highly significantly correlated with grain yield, and about 35% of variation in grain yield could be explained by the level of nitrogen fertilizer, and also showed that plant height and dry and green fodder weight were the major contributors towards grain yield since these traits explained about (57, 52, 50)% respectively of the variation of grain yield, followed by stem diameter and grain number then leaf area index, which might be a good traits to breeders for developing high yielding cultivars in sorghum

Program Pemantapan Bacaan Al-Quran dan Fardhu Ain Melalui Pembelajaran Hybrid di anak-anak Yatim Baitul Kasih Rawang - Knowledge Transfer Programme (KTP) 2014-2015

This project involves the transfer of knowledge between a university community and an orphanage. The project applies the hybrid learning method which is a combination of the traditional and computer-assisted approaches to enhance the Quranic Recital, Fardhu Ain and Arabic language programs. This KTP project is combining the theories of multimedia learning by Mayer (2001) and hybrid learning by Nicole and Retta (2006) in the activities. Mayer (2001) states that " people learn more deeply from words and pictures than from words alone", while Nicole and Retta (2006) mentioned that the hybrid learning approch is effective in carrying out 'in-depth learning'. An orphanage was chosen as the partner for this project because the orphans are in dire need of attention and support. The project helps to ensure that they are not left behind. The researchers chose to teach Quranic recital and Fardhu Ain since the skills could help to make them a better person. The religious and moral values which are embedded in these two courses may help towards producing ethical manpower in the future. This paper presents some of activities that were held in the first quarter of 2014. It was successfully run with a few modifications to the strategies and timing of the activities. Some of the children were found to be extremely weak in their Jawi script writing skill and Arabic language proficiency. Hence more time was needed to assist them during the the learning activities. This project implies the need for the government to set up a special care center for orphans under its supervision which integrates education and welfare in ensuring a brighter future for this needy group

In-vivo visualisation of the anatomical structures related to the acupuncture points Dai mai and Shen mai by MRI: A single-case pilot study

BACKGROUND: The concept of acupuncture point localisation in Traditional Chinese Medicine (TCM) is based on millenary practical experience. Modern imaging methods such as PET, MRI and SPECT have been used primary for the investigation of the mechanisms of action of acupuncture. In this pilot single-case study we have evaluated the technical possibilities for in-vivo imaging of the anatomical relations of acupuncture points using state of the art MRI. METHODS: Preliminary experiments relating to the quality of acupuncture needles under the setting of MRI were done both with stainless steel and gold needles. In a second step, in-vivo imaging was carried out. A licensed acupuncture practitioner (RM) chose two points belonging to the so-called extraordinary vessels. In 2 sequential, separate procedures, he inserted himself gold acupuncture needles using a neutral technique (known as Ping Bu Ping Xie) into the Dai mai and Shen mai points, i.e. gall bladder 26 and bladder 62. Imaging was done on a Siemens Magnetom Avanto MR scanner using a head array and body coil. Mainly T1-weighted imaging sequences, as routinely used for patient exams, were used to obtain multi-slice images. RESULTS: In the preliminary experiments only acupuncture needles made of gold showed enough stability in order to be used for further imaging procedures. Using an onion and a banana as an object, further studies showed that the gold needles produced a void defect that corresponds to the tip of the inserted needle, while at the same time an artefactually increased diameter was observed. The in-vivo experiments showed that the Dai mai point was in relation to the abdominal internal oblique muscle. The Shen mai point artefact showed up close to the longus and brevis peroneal tendons at the fibular malleolus. Side effects related to heating or burning were not observed. Improved anatomical recognition was obtained using 3D-volume rendering techniques. CONCLUSION: Through an adequate choice of acupuncture material (gold needles) as well as of ideal MRI imaging sequences it has been possible to visualize the anatomical characteristics at the acupuncture points Dai mai and Shen mai in-vivo. At the selected sites the needles showed a relation to tendino-fascial and muscular structures. These anatomical structures fit well into the recently described WOMED concept of lateral tension in which these acupuncture points play a regulatory role