Characterization of drugs prescribed to the elderly in the Family Health Strategy

Considering that the elderly are heavy consumers of medications, with significant consequences for their living conditions, the current study was intended to analyze the characteristics of such drug prescription, using the indicators proposed by the World Health Organization (WHO), and to characterize the drug classes prescribed to them in four units under the Family Health Strategy (FHS) in Marilia, Sao Paulo State, Brazil. One family health unit (FIIU) was selected by region of the city, and 100 patient charts were checked in FHU-A; 86 in B, 99 in C, and 97 in D. According to WHO drug prescription criteria, the results were similar to the recommended patterns except for drug prescription by generic name. In addition, there were significant differences between the family health units. The most frequently prescribed drug classes were for cardiovascular disorders. The health professionals showed a concern for adjusting drug prescription to rational-use criteria. However, there is a need for understanding the differences in prescription between units and a search for consensus, aimed at rational drug use.Fac Med Marilia, BR-17514000 Marilia, SP, BrazilUniv Fed Sao Paulo, Programa Posgrad Ciencias Saude, Sao Paulo, BrazilUniv Fed Sao Paulo, Programa Posgrad Ciencias Saude, Sao Paulo, BrazilWeb of Scienc

Infection with Trypanosoma cruzi TcII and TcI in free-ranging population of lion tamarins (Leontopithecus spp): an 11-year follow-up

Here, we present a review of the dataset resulting from the 11-years follow-up of Trypanosoma cruziinfection in free-ranging populations of Leontopithecus rosalia(golden lion tamarin) andLeontopithecus chrysomelas(golden-headed lion tamarin) from distinct forest fragments in Atlantic Coastal Rainforest. Additionally, we present new data regarding T. cruziinfection of small mammals (rodents and marsupials) that live in the same areas as golden lion tamarins and characterisation at discrete typing unit (DTU) level of 77 of these isolates. DTU TcII was found to exclusively infect primates, while TcI infectedDidelphis aurita and lion tamarins. The majority ofT. cruziisolates derived from L. rosaliawere shown to be TcII (33 out 42) Nine T. cruziisolates displayed a TcI profile. Golden-headed lion tamarins demonstrated to be excellent reservoirs of TcII, as 24 of 26 T. cruziisolates exhibited the TcII profile. We concluded the following: (i) the transmission cycle of T. cruziin a same host species and forest fragment is modified over time, (ii) the infectivity competence of the golden lion tamarin population fluctuates in waves that peak every other year and (iii) both golden and golden-headed lion tamarins are able to maintain long-lasting infections by TcII and TcI