Terrain classification by cluster analisys

The digital terrain modelling can be obtained by different methods belonging to two principal categories: deterministic methods (e.g. polinomial and spline functions interpolation, Fourier spectra) and stochastic methods (e.g. least squares collocation and fractals, i.e. the concept of selfsimilarity in probability). To reach good resul ts, both the fi rst and the second methods need same initial suitable information which can be gained by a preprocessing of data named terrain classification. In fact, the deterministic methods require to know how is the roughness of the terrain, related to the density of the data (elevations, deformations, etc.) used for the i nterpo 1 at ion, and the stochast i c methods ask for the knowledge of the autocorrelation function of the data. Moreover, may be useful or very necessary to sp 1 it up the area under consideration in subareas homogeneous according to some parameters, because of different kinds of reasons (too much large initial set of data, so that they can't be processed togheter; very important discontinuities or singularities; etc.). Last but not least, may be remarkable to test the type of distribution (normal or non-normal) of the subsets obtained by the preceding selection, because the statistical properties of the normal distribution are very important (e.g., least squares linear estimations are the same of maximum likelihood and minimum variance ones)

Structural variants of chromosome 9: a possibile association with hypogonadotropic hypogonadism

We report two cases of structural variations of chromosome 9 associated with hypogonadotropic hypogonadism and azoospermia in adolescent boys. One patient also had a partially imperforated urethral meatus. Histological examination revealed that both had hypotrophic and underdeveloped testes. There was no LH and FSH response to LH-RH stimulation nor was there any response to naloxone tests. Basal and HCG stimulated plasma testosterone values were below normal prepubertal levels. As the administration of gonadotrophins did not improve the clinical and hormonal findings, alternative androgen therapy was necessary to achieve secondary sexual characteristics. Although they reached a good level of androgenization, their testes were still very small and azoospermia remained, as confirmed by repeated semen analyses. A possible association between chromosome 9 polymorphisms and hypothalamo-pituitary axis abnormalities is suggested. It is hypothesized that structural variants of chromosome 9 are not unrelated occurrences. Furthermore, and in view of the fact that they can lead to a high risk of azoospermia and infertility, such variants call for clinical investigatio

Precise point positioning with single and dual-frequency multi-GNSS android smartphones

The new generation of Android smartphones is equipped with high performance Global Navigation Satellite System (GNSS) chips capable of tracking dual frequency multi-constellation data. Moreover, starting from version 9 of Android users can disable the duty cycle power saving option thus good quality pseudorange and carrier phase raw data are available thus the application of Precise Point Positioning (PPP) algorithm becomes more and more interesting. The main aim of this work is to assess the PPP performance of the first dual-frequency GNSS smartphone produced by Xiaomi equipped with a Broadcom BCM47755. The advantage of acquire dual frequency data is highlighted by comparing the performance obtained by Xiaomi with that of a single frequency smartphone the Samsung S8. The horizontal and vertical accuracy achieved by Xiaomi are of 0.51 m and 6 m respectively while those achieved by Samsung are 5.64 m for 15 m for horizontal and vertical

the tempio della consolazione in todi integrated geomatictechniques for a monument description including structuraldamage evolution in time

The Tempio della Consolazione in Todi (16th cent.) has always been one of the most significant symbols of the Umbrian landscape. Since the first times after its completion (1606) the structure has exhibited evidences of instability, due to foundation subsiding and/or seismic activity. Structural and geotechnical countermeasures have been undertaken on the Tempio and its surroundings from the 17th century until recent times. Until now a truly satisfactory analysis of the overall deformation and attitude of the building has not been performed, since the existing surveys record the overhangs of the pillars, the crack pattern or the subsidence over limited time spans. Describing the attitude of the whole church is in fact a complex operation due to the architectural character of the building, consisting of four apses (three polygonal and one semicircular) covered with half domes, which surround the central area with the large dome. The present research aims to fill the gap of knowledge with a global study based on geomatic techniques for an accurate 3D reconstruction of geometry and attitude, integrated with a historical research on damage and interventions and a geotechnical analysis. The geomatic survey results from the integration of different techniques: GPS-GNSS for global georeferencing, laser scanning and digital photogrammetry for an accurate 3D reconstruction, high precision total station and geometric leveling for a direct survey of deformations and cracks, and for the alignment of the laser scans. The above analysis allowed to assess the dynamics of the cracks occurred in the last 25 years by a comparison with a previous survey. From the photographic colour associated to the point cloud was also possible to map the damp patches showing on the domes intrados, mapping their evolution over the last years

THE CATHEDRAL OF S. LORENZO IN PERUGIA AND THE HYPOGEAL SPACES. GEOMATIC TECHNIQUES FOR SPATIAL INVESTIGATIONS AIMED AT THE KNOWLEDGE AND INTERPRETATION OF THE ORIGIN OF THE TRANSEPT

The area of the monumental complex of the Cathedral and the rectories of S. Lorenzo, located on the “acropolis” of Perugia, has been for more than two thousand years the main religious and civil reference site of all populations since the origin of the city of Perugia. The aim of this research was to survey the monumental complex of the Cathedral of San Lorenzo through the use of various geomatic techniques, with particular attention to the areas of the apse, the transept, the attic, the upper courtyard and the lower one, together with the hypogeal rooms of the Capitular Museum underlying the church, including important and impressive ruins as a portion of an Etruscan terracing wall (2nd century BC).The complex is extremely articulated, so it was necessary to correlate external and hypogeal internal spaces; the site is also characterized by the existence of numerous archaeological traces of various origins, resulting from the succession of events developed over the centuries and countless works that have been integrated, juxtaposed and in some cases replaced by previous ones. All this circumstances contribute to make not easy the understanding of the planimetric and altimetric relationships existing between the different parts and the identification of the real context of the architectural elements is equally complex. The need to connect different areas of the monumental complex located at different levels (from hypogeal rooms and vaults to the church, the attic and the external squares and streets) has required a coordinated and integrated use of geomatic techniques such as precision GNSS positioning (outside the building) and the creation of a very articulated three-dimensional geodetic network connecting the external GNSS vertices with the internal reference points and targets placed in the different areas to frame in a unique global datum the subsequent detailed surveys performed with LIDAR and photogrammetric techniques, so that the single scans and local surveys could be assembled to form a unique 3D model. Among the many aspects highlighted, in particular, it was possible to understand the genesis of the cathedral transept, whose size was dictated by an imposing Etruscan wall. Until now the ruins of the ancient cathedral complex were known - referring to three different buildings, the cathedral, the dodecagonal bell tower and the chapel of Sant'Ercolano - incorporated into the side of the basilical body in front of Piazza IV Novembre. From additional ruins attributed to the structure of the ancient cathedral, it was obtained that the level of the floor of the church has been substantially maintained in the current cathedral.</p

Adverse pathophysiological influence of early testosterone therapy on the testes of boys with higher grade sex chromosome aneuploidies (HGAs): a retrospective, cross-sectional study

Purpose: Higher grade aneuploidies (HGAs) of the male sex chromosomes are a rare genetic group of pathologies caused by nondisjunction meiotic events. The aim of this study was to evaluate the impact of early androgenic therapy on the testicular secretory hormone profile, and the pathophysiological implications. Patients and methods: In this cross-sectional study, 18 HGA subjects aged 6–8&nbsp;years were recruited. They were divided into two groups, based on whether or not they had previously undergone testosterone therapy (group 1: 11 untreated subjects; group 2: 7 treated subjects). Serum FSH, LH, testosterone (T), inhibin B (INHB) and anti-Müllerian hormone (AMH) were determined, and auxological parameters were assessed. Five group 1 patients and four group 2 patients were treated with hCG (human chorionic gonadotropin) for inguinal cryptorchidism; their hormone profile and auxological parameters were assessed both pre- and post-hCG treatment. Results: Group 1 subjects showed significantly higher testicular volume and higher levels of AMH and INHB (p &lt; 0.0001). Subjects who had undergone hCG therapy showed a significantly higher testicular volume, penis length (respectively, p = 0.008 and p = 0.0005 for group 1 and p = 0.04 and p = 0.001 for group 2) and T (p = 0.005 for group 1 and p = 0.004 for group 2). Conclusions: HGA patients undergoing early testosterone therapy show an earlier and persistent suppression of testicular secretory function. At this age, the testes are still responsive to stimulation with hCG. The selection of patients to be treated must be accompanied by a thorough clinical and hormonal evaluation

Integrated Geomatic Techniques for Georeferencing and Reconstructing the Position of Underground Archaeological Sites: The Case Study of the Augustus Sundial (Rome)

A large part of the archaeological remains still to be discovered and excavated are not in remote and depopulated areas of the earth but are often beneath urban centres that have buried them with centuries of debris and later constructions. Excavating in these contexts is much more complex than digging in rural or sparsely inhabited areas because of the constraints imposed by existing buildings and infrastructure. It should also be considered that within an urbanised area, any archaeological remains are concentrated in the subsoil of the historic centre, which is, therefore, often surmounted by buildings that are more recent than the remains but historical as well, and thus, of considerable value and vulnerability. For this reason, an archaeological excavation in an urban area must be preceded by a real feasibility study, where the potential risks for the structures above are minimised and accurately quantified. In many situations, as in the case under study, the discovery of a small segment of a structure is the only clue to reconstruct the development of the remaining part still to be excavated, which may stretch tens or hundreds of metres away from the measurable part. As a consequence, an error of a few centimetres in the survey of the excavated part can lead to errors of metres in estimating the positions of the far parts still to be excavated, and this, in many cases, as in the one under study, must absolutely be avoided. In practice, high-precision geomatic surveys, in support of the archaeological and historical interpretation of the observable structures, will help to establish the exact locations to possibly continue the excavations, helping the accurate planning of the excavation itself. Here, we have shown how the various techniques, compared to each other, have made it possible to reconstruct the location of a short stretch (less than 7 metres) of the Emperor Augustus' Sundial, the only currently visible evidence of a scientific instrument of imposing dimensions (tens of metres in length and height) that served to define some of the characteristics of the calendar that we still use today. The portion of the sundial currently observable, according to the most reliable hypotheses, is located approximately at one end of a structure and extends for several tens of metres. The accurate positioning of the observable parts in a geodetic reference system will enable to identify with certainty the possible areas in which excavation may continue and will also allow to accurately reconstruct the principle of operation of the sundial through an approach that could be defined as "reverse engineering" of the scientific instrument itself. The aim of this work is to study and thus define the combination and integration of existing geomatic techniques for this specific field of applicatio

A narrow band neutrino beam with high precision flux measurements

The ENUBET facility is a proposed narrow band neutrino beam where lepton production is monitored at single particle level in the instrumented decay tunnel. This facility addresses simultaneously the two most important challenges for the next generation of cross section experiments: a superior control of the flux and flavor composition at source and a high level of tunability and precision in the selection of the energy of the outcoming neutrinos. We report here the latest results in the development and test of the instrumentation for the decay tunnel. Special emphasis is given to irradiation tests of the photo-sensors performed at INFN-LNL and CERN in 2017 and to the first application of polysiloxane-based scintillators in high energy physics.Comment: Poster presented at NuPhys2017 (London, 20-22 December 2017). 5 pages, 2 figure

Coseismic and initial postseismic slip of the 2009 Mw 6.3 l’Aquila earthquake, Italy, from GPS measurements

Here we report the preliminary results of GPS data inversions for coseismic and initial afterslip distributions of the Mw 6.3 2009 April 6 L’Aquila earthquake. Coseismic displacements of continuous and survey-style GPS sites, show that the earthquake ruptured a planar SW-dipping normal fault with ∼0.6 m average slip and an estimated moment of 3.9 × 1018 Nm. Geodetic data agree with the seismological and geological information pointing out the Paganica fault, as the causative structure of the main shock. The position of the hypocentre relative to the coseismic slip distribution supports the seismological evidence of southeastward rupture directivity. These results also point out that the main coseismic asperity probably ended downdip of the Paganica village at a depth of few kilometres in agreement with the small (1–10 cm) observed surface breaks. Time-dependent post-seismic displacements have been modelled with an exponential function. The average value of the estimated characteristic times for near-field sites in the hanging-wall of the fault is 23.9 ± 5.4 d. The comparison between coseismic slip and post-seismic displacements for the first 60 d after the main shock, shows that afterslip occurred at the edges of the main coseismic asperity with a maximum estimated slip of ∼25 cm and an equivalent seismic moment of 6.5 × 1017 Nm. The activation of the Paganica fault, spatially intermediate between the previously recognized main active fault systems, suggests that strain accumulation in the central Apennines may be simultaneously active on distinct parallel fault systems.Published1539–15461.1. TTC - Monitoraggio sismico del territorio nazionale1.9. Rete GPS nazionaleJCR Journalrestricte