Diagnosing Heart Diseases For Type 2 Diabetic Patients By Cascading The Data Mining Techniques

Motivated by the world-wide increasing mortality of heart disease patients each year, researchers have been using data mining techniques to help health care professionals in the diagnosis of heart disease. Heart disease is the leading cause of death in the world over the past 10 years. Researchers have been using several data mining techniques to help health care professionals in the diagnosis of heart disease. To review the primary prevention studies that focused on the development, validation and impact assessment of a heart disease risk model, scores or rules that can be applied to patients with type 2 diabetes. Efficient predictive modeling is required for medical researchers and practitioners. Attribute values measurement using entropy and information gain parameters. This study proposes Hybrid type 2 diabetes Prediction Model which uses Improved Fuzzy C Means (IFCM) clustering algorithm aimed at validating chosen class label of given data in which incorrectly classified instances are removed and. pattern extracted from original data. Support Vector Machine (SVM) algorithm is used to build the final classifier model by using the k-fold cross-validation method. The aim of this paper is to highlight all the techniques and risk factors that are considered for diagnosis of heart disease. This paper will provide a roadmap for researchers seeking to understand existing automated diagnosis of heart disease

Diagnosing genital tuberculosis in female infertility by clinical, histopathological, culture and polymerase chain reaction techniques: an evaluative study

Background: In developing countries, the genital tract tuberculosis is one of the common causes of tubal damage leading to infertility. Objective of present study was to evaluate the efficacy of Histopathological examination (HPE), culture and Polymerase Chain Reaction Technique in diagnosing genital tuberculosis.Methods: It was a prospective evaluative study. 173 women were subjected to investigations for tuberculosis. AFB smear, culture and HPE examination and PCR testing were carried out on 173 endometrial samples, 81 POD fluid and 52 urine samples. Based on the clinical profile and laparoscopic findings a diagnostic criterion was derived to suspect GTB and the specific diagnostic tests were evaluated against this diagnostic criterion.Results: Based on the diagnostic criteria, tuberculosis was suspected in 61 of the 153 cases.   AFB smear was positive in 4.6%, culture was positive in 3.5%, HPE positive in 4.0% and PCR was positive in 28.1% of cases. On evaluating against the diagnostic criteria, the sensitivity of PCR, HPE, culture and AFB smear were; 44.3%, 8.2%, 6.6% and   6.7% respectively.  PCR was positive in 18 of the 92 cases in whom GTB was not suspected. The PCR results were negative in 34 of the 61 clinically suspected cases.Conclusions: This study has shown that HPE, AFB smear and culture have low pick up rates. PCR is found to be useful in confirming diagnosis in clinically suspected cases. False negative PCR was an important limitation in this study

Three-dimensional modeling of the neutron spectrum to infer plasma conditions in cryogenic inertial confinement fusion implosions

Neutron-based diagnostics are typically used to infer compressed core conditions such as areal density and ion temperature in deuterium–tritium (D–T) inertial confinement fusion (ICF) implosions. Asymmetries in the observed neutron-related quantities are important to understanding failure modes in these implosions. Neutrons from fusion reactions and their subsequent interactions including elastic scattering and neutron-induced deuteron breakup reactions are tracked to create spectra. It is shown that background subtraction is important for inferring areal density from backscattered neutrons and is less important for the forward-scattered neutrons. A three-dimensional hydrodynamic simulation of a cryogenic implosion on the OMEGA Laser System [Boehly et al., Opt. Commun. 133, 495 (1997)] using the hydrodynamic code HYDRA [Marinak et al., Phys. Plasmas 8, 2275 (2001)] is post-processed using the tracking code IRIS3D. It is shown that different parts of the neutron spectrum from the view can be mapped into different regions of the implosion, enabling an inference of an areal-density map. It is also shown that the average areal-density and an areal-density map of the compressed target can be reconstructed with a finite number of detectors placed around the target chamber. Ion temperatures are inferred from the width of the D–D and D–T fusion neutron spectra. Backgrounds can significantly alter the inferred ion temperatures from the D–D reaction, whereas they insignificantly influence the inferred D–T ion temperatures for the areal densities typical of OMEGA implosions. Asymmetries resulting in fluid flow in the core are shown to influence the absolute inferred ion temperatures from both reactions, although relative inferred values continue to reflect the underlying asymmetry pattern. The work presented here is part of the wide range of the first set of studies performed with IRIS3D. This code will continue to be used for post-processing detailed hydrodynamic simulations and interpreting observed neutron spectra in ICF implosions

Florid genital tuberculosis co-existing with adenomyosis and evading diagnosis

When tuberculosis affects genital organs of young females, the disease often remains silent or may present with symptoms which are common to other Gynaecological conditions as well. The diagnosis of genital tuberculosis is challenging and the diagnosis can be missed even with extensive investigations including molecular studies. A case of florid tuberculosis affecting the uterus, cervix, ovaries and tubes, co-existing with adenomyosis of the uterus and the cold abscess masquerading as bilateral ovarian endometriomas is reported

Profile of cutaneous adverse drug reactions of carbamazepine

Background: Carbamazepine, a commonly used antiepileptic drug is known to produce adverse effects including dangerous reactions like cutaneous hypersensitivity reactions such as drug induced hypersensitivity syndrome (DHS), Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). The FDA released a warning that serious and potentially fatal skin reactions may occur after carbamazepine in patients positive for the HLA-B*1502 allele which occurs almost exclusively in patients with ancestry across broad areas of Asia, including South Asian Indians. This study profiles the cutaneous adverse drug reactions reported in this institute over a period of 3 years.Methods: This retrospective study was conducted at Tirunelveli Medical College Hospital by analysing patient case records based on adverse drug reactions reported between August 2014 and July 2017 in the adverse drug reaction monitoring centre. The age, gender, diagnosis, type of cutaneous ADR, duration of treatment, seriousness of reaction and outcome were recorded and analysed.Results: Among the total 25 reactions 36% were benign and 64% were severe reactions. According to Pharmaco vigilance Program of India 80% of the reactions were serious and 20% non serious. The commonest benign skin reaction was maculopapular eruption. SJS and TEN were the two very serious reactions which affected 8 patients totally. Exfoliative dermatitis was reported in 7 patients and Drug Hypersensitivity Syndrome (DHS) in one patient.Conclusions: Severe cutaneous reactions occur after carbamazepine and prevention of ADR requires prediction of predisposition which requires special studies of HLA or genomic assessment. These are the issues of interest for future research

Kontestasi Kelian Adat dalam Pemilukada Serentak di Kota Denpasar Tahun 2015

Contestation of Kelian Adat in the General Election in Denpasar in 2015, became an interesting subject of research by explaining the position of the Kelian Adat as a bridge to facilitate political activity that touches Banjar Adat. Reduced public confidence in the political parties, to make the political parties are not the only supporters of victory. Kelian Adat as Banjar Adat leaders have an important role in mobilizing the masses. So one way to expand the domination of the Kelian Adat is used to facilitate the achievement of political objectives. The purpose of this study was to determine and describe the Contestation of Kelian Adat in the General Election in Denpasar in 2015. The theory used political elite theory. The method used in this research is descriptive qualitative method, while the technique of collecting data through observation, interview and documents. The results of this study found that, in the election Kelian Adat give major influence on the voting results of candidates. Given the way to condition the award of a pair of candidates raises a strategy known as suryak siu or briuk siu, where this condition is togetherness Balinese people in taking an action and should be uniform with no difference. In this study concluded that the contestation of Kelian Adat made in the implementation of the election simultaneously in Denpasar in 2015 with the Kelian Adat competing to bring in uniformity of manners Banjar voters