Analytical study of lightweight acoustic shrouds for shuttle experiments and payloads

Results are presented of acoustic tests performed on an STS payload shroud simulator to determine the effects of a helium filled liner on the noise reduction characteristics. The basic test program included the following configurations: (1) bare shroud (baseline configuration); (2) shroud with empty liner; (3) shroud with liner filled with air; and (4) shroud with liner filled with helium. The results indicate negligible effects from the helium. Configurations for liner filled with air, and liner filled with helium were also tested. The data from these configurations indicate increased noise reduction from the use of helium

Monitoring cardiovascular function in the primate under prolonged weightlessness

Monitoring cardiovascular function in primates under prolonged weightlessnes

A low power blood flow transmitter. Transmission of cardiovascular response to weightlessness Progress report, 1 Mar. - 31 May 1970

Low power blood flow transmitter to determine cardiovascular response to weightlessnes

Analytical trade study of the STS payload environment

The current predicted acoustic environment for the shuttle orbiter payload bay will produce random vibration environments for payload components and subsystems which potentially will result in design, weight and cost penalties if means of protecting the payloads are not developed. Results are presented of a study to develop, through design and cost effectiveness trade studies, conceptual noise suppression device designs for space shuttle payloads. The impact of noise suppression on environmental levels and associated test costs, and on test philosophy for the various payload classes is considered with the ultimate goal of reducing payload test costs. Conclusions and recommendations are presented

Aerospace systems pyrotechnic shock data /ground test and flight/. Volume 4 - Lockheed data and analyses Final report, Jun. 1968 - Mar. 1970

Compilation of shock loads on spacecraft structures produced by actuation of pyrotechnics and explosive devices - Vol.

Aerospace systems pyrotechnic shock data /ground test and flight/. Volume 6 - Pyrotechnic shock design guidelines manual, revision A Final report, Jun. 1968 - Mar. 1970

Design of structures and equipment to reduce shock loads induced by pyrotechnics and explosive devices - Vol.

Patent Law in a Nutshell

This book provides a concise description of the fundamentals of U.S. patent law. The book is organized in sixteen chapters, covering topics such as the foundations of patent law, patent acquisition, anticipation, patent eligibility, patent claims, construction, and remedies. The book discusses the key statutes, rules, and cases that have shaped present-day patent law doctrine

Patent Law in a Nutshell

This book provides a concise description of the fundamentals of U.S. patent law. The book is organized in sixteen chapters, covering topics such as the foundations of patent law, patent acquisition, anticipation, patent eligibility, patent claims, construction, and remedies. The book discusses the key statutes, rules, and cases that have shaped present-day patent law doctrine

Endothelial Lipase Concentrations Are Increased in Metabolic Syndrome and Associated with Coronary Atherosclerosis

BACKGROUND: Endothelial lipase (EL), a new member of the lipase family, has been shown to modulate high-density lipoprotein (HDL-C) metabolism and atherosclerosis in mouse models. We hypothesized that EL concentrations would be associated with decreased HDL-C and increased atherosclerosis in humans. METHODS AND FINDINGS: Healthy individuals with a family history of premature coronary heart disease (n = 858) were recruited as part of the Study of the Inherited Risk of Atherosclerosis. Blood was drawn in the fasting state before and, in a subgroup (n = 510), after administration of a single dose of intravenous heparin. Plasma lipids were measured enzymatically, lipoprotein subclasses were assessed by nuclear magnetic resonance, and coronary artery calcification (CAC) was quantified by electron beam computed tomography. Plasma EL mass was measured using a newly developed enzyme-linked immunosorbent assay. Median EL mass in pre-heparin plasma was 442 (interquartile range = 324–617) ng/ml. Median post-heparin mass was approximately 3-fold higher, 1,313 (888–1,927) ng/ml. The correlation between pre-heparin EL mass and post-heparin EL mass was 0.46 (p < 0.001). EL mass concentrations in both pre- and post-heparin plasma significantly correlated with all NCEP ATPIII-defined metabolic syndrome factors: waist circumference (r = 0.28 and 0.22, respectively, p < 0.001 for each), blood pressure (r = 0.18 and 0.24, p < 0.001 for each), triglycerides (r = 0.22, p < 0.001; and 0.13, p = 0.004), HDL cholesterol (r = –0.11, p = 0.002; and –0.18, p < 0.001), and fasting glucose (r = 0.11 and 0.16, p = 0.001 for both). EL mass in both routine (odds ratio [OR] = 1.67, p = 0.01) and post-heparin (OR = 2.42, p = 0.003) plasma was associated with CAC as determined by ordinal regression after adjustment for age, gender, waist circumference, vasoactive medications, hormone replacement therapy (women), and established cardiovascular risk factors. CONCLUSIONS: We report, to our knowledge for the first time, that human plasma EL concentrations, in both post-heparin and routine pre-heparin plasma, are significantly associated with metabolic syndrome features and with subclinical atherosclerosis. EL may be a pro-atherogenic factor in humans, especially in overweight individuals and those with metabolic syndrome

Aerospace systems pyrotechnic shock data - Ground test and flight. Volume 2 - Data Final report, Jun. 1968 - Mar. 1970

Pyrotechnic shock data associated with structure cutting charges consisting of mild detonating fuse and flexible linear shaped charge - Vol.