L’intoxication Par Les Cremes Eclaircissantes Au Maroc Profil Epidemiologique

Objectives: In Morocco the large number of cosmetic products is sold freely without control or registration. The lack of knowledge of the composition of these products make therapeutic management in case of poisoning very difficult and sometimes causes unnecessary health spending even if these poisoning are often benign. The objective of this study is to establish the epidemiological profile of a poisoning by lightening creams collected at the Moroccan Poison Control and Pharmacovigilance Center. Methods: This is a retrospective study of poisoning case by lightening creams collected at the Moroccan Poison Control and Pharmacovigilance Center between 1992 and 2008. Results: During the study period, 95 cases were collected. The mean age is 20 years ± 1.4 [1-70 ans], and the F/M sex ratio is 1.73. In 90 (95%) cases, the route of poisoning was oral. The Suicide attempts represent 33 % of cases. Women are often voluntarily intoxicated. However, men were concerned by involuntary intoxication (p = 0.003). Eighty three cases were urban (87%) and 90 cases occured at home (95%). The digestive disorders were found in 68 cases associeted or not with a neurological disorders (33 cases), cardiovascular disorders (14 cases), and respiratory distress (6 cases). The evolution was favorable in all cases. Conclusions: The implementation of the new law recording to the registration of cosmetic products in the ministry of health before marketing will ensure certainly a better orientation of the poisoning case management and improve the patient safety

Cartography of Suicide-Related Health Indicators and Suicide Attempts in Morocco

The present work consists of a retrospective study of suicidal intoxication during a period stretching from January 1980 to December 2013, reported to the Poison Control and Pharmaco-vigilance Center of Morocco through two systems of data collection: Toxicological Information and Toxico-vigilance. The objective is to determine the spatio-temporal evolution of the incidence, lethality and mortality related to suicides and suicide attempts through intoxication in Morocco. During the study period, the average annual number of suicidal intoxications was 707 cases. All regions of Morocco have been affected but at variable rates. The average age of the victims is 24.39 ± 0.08 years, with a sex ratio of 2.41 in favor of the female sex. In the space of 34 years, the incidence is 2.4 per 100,000 inhabitants, the mortality is 0.67 per million inhabitants and the lethality is 0.08%. The annual increase in biological indicators makes suicides and suicide attempts a public health problem, through hospital care and the resulting socio-economic and psychological consequences. This problem seems much more common in urban areas and particularly in the big cities of Morocco

MODELING OF ACTIONS TO TAKE AFTER A SCORPION STING AND DEVELOPING A WEB BASED INFORMATION SYSTEM TO TRACK THE DIFFERENT INDICATORS SYSTEMATICALLY

To take the quickest and the correct decision when a scorpion stingsis decisive in terms of patient rescue. Based on a long experience andcollected information about envenomation, Anti Poison andPharmacovigilance Center of Morocco (CAPM) developed a guideline withclear actions to help the patients.European Scientific Journal April 2014 edition vol.10, No.12 ISSN: 1857 – 7881 (Print) e - ISSN 1857- 7431118The application of information technology in health sector has grownexponentially over the last years. This research aimed to model a health caresystem and make it easier to use by the health professionals. It will allow theclinician to monitor the evolution of the different vital signs and eventuallysuggest the best hospitalization (type of drug, reanimation, release...). Themain objective is to improve effectiveness and efficiency.The developed application contains sensible data, therefore the generalconcept is constructed to be secure. Furthermore, it is web oriented, in orderto facilitate the communication between the various sanitaire structures. Theprogram helps enormously to gather important statistics and analysis

Geographical distribution of health indicators related to snake bites and envenomation in Morocco between 1999 and 2013

OBJECTIVES Envenomation from snake bites is a significant cause of morbidity and mortality worldwide. The aim of this study was to describe the epidemiological features of snake bites in Morocco and to evaluate time-space trends in snake bite incidence, the mortality rate, and the case-fatality rate. METHODS This is a retrospective study of snake bite cases reported to the Moroccan Poison Control Center between 1999 and 2013. RESULTS During the study period, 2,053 people were bitten by snakes in Morocco. Most victims were adults (55.4%). The average age of the patients was 26.48±17.25 years. More than half of the cases (58.1%) were males. Approximately 75% of snake bites happened in rural areas, and 85 deaths were recorded during this period. The incidence of snake bites remained generally steady over the 15-year period of this study, with a marked increase noted since 2012. The mortality rate has increased slightly, from 0.02 deaths per 100,000 inhabitants in 1999 to 0.05 in 2013. The geographical distribution of snake bite cases in the regions of Morocco showed that Tanger-Tétouan had the highest annual incidence of snake bites (1.41 bites per 100,000 inhabitants). However, the highest annual mortality rates were recorded in the Guelmim-Es Semara and Souss-Massa-Drâa regions (0.09 deaths per 100,000 inhabitants for both regions). CONCLUSIONS The geographical distribution of the incidence, mortality, and case-fatality rates of snake bites in Morocco showed large disparities across regions during the three 5-year periods included in this study, meaning that certain areas can be considered high-risk for snake bites

Estimation De L’exhaustivité De La Surveillance Des Intoxications Médicamenteuses Dans La Région De Tanger-Tétouan-Al Hoceima, Maroc, 2014-2016

The aim of this study is to estimate the completeness of drug poisoning surveillance in the region of Tanger-Tétouan-Al Hoceima in Morocco. The study deals with cases of drug poisoning identified by the Moroccan Anti Poison Control Center (MPCC) and the cases collected by the registers of the provincial hospitals of the studied region between 2014 and 2016 period. The completeness of the surveillance was studied by the capture-recapture method. During the study period, 835 cases of drug poisoning were identified by the MPCC and 892 cases from the registers of hospitals in the region. The number of duplicates was 78. The capture-recapture method made it possible to estimate the total number of cases at 9 549 (95% CI: 8,199-10,900). The completeness of surveillance is estimated at 8.74% from MPCC and 9.34% from hospital registers in the region. The capture-recapture method provided limited completeness of monitoring for drug poisoning in the study area. Improved awareness of doctors about the declaration is necessary to strengthen the system of surveillance of poisoning in Morocco

LES RÉACTIONS LOCALES LIÉES AU VACCIN BCG

To evaluate the frequency and severity of associated local reactions to BCG a retrospective study was conducted on the notified in Moroccan Centre Anti Poison and Pharmacovigilance. During this period, 295 cases have been reported following vaccination with BCG local natureMales were the most concerned with 57%. Infants are much more represented (61%) than other age groups. The most local reactions are observed: becegites (37%), abscesses (20%), rash (16%), ulcers (15%), and fistula (12%). Accompanying signs of these local reactions are usually represented by a fever (6%) and lymphadenopathy (2%). BCG was injected intradermally in 87% of cases, followed by the intramuscular route (8%) and the subcutaneous route in 5% of cases. According to the classification of severity of the WHO ART, these reactions were severe in 18% of cases, moderate in 69% and severe in 14% of cases. The relation of cause and effect between BCG vaccination and the occurrence of local reactions is well established with 46% of probable cases and 7% of cases while some is possible in 46%, and excluded in 1%. The outcome was favorable in 85%, 14% recovered with sequelae and 1% was fatal

Profil Épidémiologique Des Avortements Provoqués Au Maroc (1992/2014)

On the set of the poisonings brought together in the the Moroccan Anti Poison Control Center (MPCC) for a period spread on 22ans (1992/2014), 169 cases of abortion caused by poisoning were recorded. The objective of this work is to describe the epidemiological characteristics and to determine the specific lethality of abortions caused in Morocco between 1992 and 2014 by basing itself on a retrospective study of the cases of abortions. During this period 169 cases of abortion caused by poisoning were declared to the MPCC by means of telephone and mail, the region which knew the maximum of the cases is Rabat Salé Zemmour Zair, the environment rural prevail the risks of abortion with 90 %, the average age was 28,09±11,81, the evolution is generally positive

Les Effets Indésirables Digestifs De La Chimiothérapie : Cas Des Patients De L’institut National D’oncologie De Rabat (Maroc)

An adverse reaction of an anticancer drug is a harmful and an unintended reaction by patient suffering from cancer disease who is often polymedicated. The treatment of cancers by anti-cancer molecules produces serious adverse drug effects. The main purpose of this paper is to present and evaluate the digestive adverse effects involved in anti-cancer drugs and their potential of correlation to anticipate, prevent and improve the quality of care of patient suffering from cancer disease. This is a prospective study that that enrolled 147 patients seen between January 25 and June 25, 2009 with adverse drug reactions due to an anticancer treatment. Breast and cavum cancers present 34% of cases. The average age was 46.52 years. The sex ratio (M / F) was 0.33. During the study period 283 Adverse drug effects of anticancer drugs were collected with a predominance (132) adverse digestive effects and 32 anticancer drugs were counted on all medical prescriptions. Nausea and vomiting are the most common side effects, sometimes very severe. The availability of anti-emetics in the family of 5-HT3 serotoninergic antagonists has considerably improved the experience of patients undergoing anticancer chemotherapy, hence the importance of pharmacovigilance as a tool is to improve the quality of anticancer care

INTOXICATION PAR LE PEROXYDED’ HYDROGENE DESTINE A LA DECOLORATION DE CHEVEUX: DONNEES DU CENTRE ANTIPOISON ET DE PHARMACOVIGILANCE DU MAROC

To assess the extent and severity of poisoning by hydrogen peroxide dye hair used as the Moroccan population, a retrospective epidemiological study of all cases of poisoning reported, collected by the Moroccan poison control and pharmacovigilance center, between 1987 and 2011 was realized. The center has received 43 reports. The mean age was 18 ± 2 years [0.1-50 years] and the female / male ratio was 2. The majority of cases of poisoning were occurred in th urban area (35 cases) and at home (31 cas). The digestive disorders were found in 17 cases, associeted or not with a neurological disorders (2 cases), cardiovascular disorders (1 case) and skin disorders e (1 case).Twenty patients were referred to the emergency care unit). A symptomatic treatment was ordered in 26 cases and gastrointestinal descontamination in 11 cases. The evolution was favorable in all cases

Les Intoxications Accidentelles Par Les Pesticides Au Maroc Entre 2008-2014: Evolution Et Facteurs De Risque

The aim of this study was to determine the epidemiological profile of accidental poisoning by pesticides. A retrospective study of poisoning cases, declared between January 2008 to December 2014 at the Moroccan Anti poisoning and Pharmacovigilance Center (MAPPC), was conducted. During the study period, 4 110 acute accidental poisoning by pesticides cases were collected. The average age was of patients 19, 24±0,25 years. The sex-ratio (female/male) was 0.95. Poisoning mainly concerned adults between the ages of 20 and 74 (about 43%). The pesticide poisoning occurs more often in urban zones with 54.1%. These were mainly poisonings that occurred at home in 70.5% of cases. Patients were mostly symptomatic (about 65%), these poisonings occurred mainly during the spring mostly in the spring (32%) and summer (29%). Insecticides were the most commonly incriminated in 64, 13% of cases, followed by rats, pesticides, and herbicides with respectively 29%, 3.42% and 0.85%. The declarations came from all regions of Morocco, the highest incidence was recorded in the Tadla-Azilal region (4.04 per 100 000 inhabitants). The Fes Boulemane region showed a significant lethality of 6.43%. Among the 3,077 patients for whom the evolution was known, 98.1% had progressed favorably. 47 cases of death were recorded with a lethality of 1.2%