4,205 research outputs found
Tumbleweeds and airborne gravitational noise sources for LIGO
Gravitational-wave detectors are sensitive not only to astrophysical
gravitational waves, but also to the fluctuating Newtonian gravitational forces
of moving masses in the ground and air around the detector. This paper studies
the gravitational effects of density perturbations in the atmosphere, and from
massive airborne objects near the detector. These effects were previously
considered by Saulson; in this paper I revisit these phenomena, considering
transient atmospheric shocks, and the effects of sound waves or objects
colliding with the ground or buildings around the test masses. I also consider
temperature perturbations advected past the detector as a source of
gravitational noise. I find that the gravitational noise background is below
the expected noise floor even of advanced interferometric detectors, although
only by an order of magnitude for temperature perturbations carried along
turbulent streamlines. I also find that transient shockwaves in the atmosphere
could potentially produce large spurious signals, with signal-to-noise ratios
in the hundreds in an advanced interferometric detector. These signals could be
vetoed by means of acoustic sensors outside of the buildings. Massive
wind-borne objects such as tumbleweeds could also produce gravitational signals
with signal-to-noise ratios in the hundreds if they collide with the
interferometer buildings, so it may be necessary to build fences preventing
such objects from approaching within about 30m of the test masses.Comment: 15 pages, 10 PostScript figures, uses REVTeX4.cls and epsfig.st
16 x 25 Ge:Ga Detector Arrays for FIFI LS
We are developing two-dimensional 16 x 25 pixel detector arrays of both
unstressed and stressed Ge:Ga photoconductive detectors for far-infrared
astronomy from SOFIA. The arrays, based on earlier 5 x 5 detector arrays used
on the KAO, will be for our new instrument, the Far Infrared Field Imaging Line
Spectrometer (FIFI LS). The unstressed Ge:Ga detector array will cover the
wavelength range from 40 to 120 microns, and the stressed Ge:Ga detector array
from 120 to 210 microns. The detector arrays will be operated with multiplexed
integrating amplifiers with cryogenic readout electronics located close to the
detector arrays. The design of the stressed detector array and results of
current measurements on several prototype 16 pixel linear arrays are reported.
They demonstrate the feasibility of the current concept. ***This paper does not
include Figures due to astro-ph size limitations. Please download entire file
at http://fifi-ls.mpe-garching.mpg.de/spie.det.ps.gz ***Comment: 8 pages, SPIE Proceedings, Astronomical Telescopes and
Instrumentation 200
Too Late! Influence of Temporal Delay on the Neural Processing of One’s Own Incidental and Intentional Action-Induced Sounds
The influence of delayed auditory feedback on action evaluation and execution of real-life action-induced sounds apart from language and music is still poorly understood. Here, we examined how a temporal delay impacted the behavioral evaluation and neural representation of hurdling and tap-dancing actions in a functional magnetic resonance imaging (fMRI) experiment, postulating that effects of delay diverge between the two, as we create action-induced sounds intentionally in tap dancing, but incidentally in hurdling. Based on previous findings, we expected that conditions differ regarding the engagement of the supplementary motor area (SMA), posterior superior temporal gyrus (pSTG), and primary auditory cortex (A1). Participants were videotaped during a 9-week training of hurdling and tap dancing; in the fMRI scanner, they were presented with point-light videos of their own training videos, including the original or the slightly delayed sound, and had to evaluate how well they performed on each single trial. For the undelayed conditions, we replicated A1 attenuation and enhanced pSTG and SMA engagement for tap dancing (intentionally generated sounds) vs. hurdling (incidentally generated sounds). Delayed auditory feedback did not negatively influence behavioral rating scores in general. Blood-oxygen-level-dependent (BOLD) response transiently increased and then adapted to repeated presentation of point-light videos with delayed sound in pSTG. This region also showed a significantly stronger correlation with the SMA under delayed feedback. Notably, SMA activation increased more for delayed feedback in the tap-dancing condition, covarying with higher rating scores. Findings suggest that action evaluation is more strongly based on top–down predictions from SMA when sounds of intentional action are distorted
Phoenix dactylifera L. sap enhances wound healing in Wistar rats : Phytochemical and histological assessment
Acknowledgment Financial support of the Tunisian Ministry of Higher Education and Scientific Research is gratefully acknowledged.Peer reviewedPostprin
Tailoring the gradient ultrafine-grained structure in low-carbon steel during drawing with shear
Conventional drawing and drawing with shear were conducted on the rods of low-carbon steel. Deformation by simple drawing forms basically a homogenous structure and leads to a uniform change in microhardness along the billet volume. A comparative analysis of the models of these processes showed that shear drawing of steel at room temperature reduces energy characteristics in half, normal forces on the die – by 1,8, and enhances the strain intensity from 0,5 to 1,6. During drawing with shear, strain-induced cementite dissolution occurs and a gradient structure is formed, which increases the microhardness of the surface layer up to values close to 7 000 MPa
Reforma del puente San Francisco-Oakland
Como consecuencia del creciente tráfico por carretera todos los puentes construidos, con anterioridad a nuestros días, resultan incapaces de absorber la intensidad actual de dicho tráfico y, por ello, tanto los puentes como las propias carreteras experimentan una apremiante necesidad de reforma para poder seguir el movimiento ascendente de aquél
The neurophysiology of continuous action monitoring.
Monitoring actions is essential for goal-directed behavior. However, as opposed to short-lasting, and regularly reinstating monitoring functions, the neural processes underlying continuous action monitoring are poorly understood. We investigate this using a pursuit-tracking paradigm. We show that beta band activity likely maintains the sensorimotor program, while theta and alpha bands probably support attentional sampling and information gating, respectively. Alpha and beta band activity are most relevant during the initial tracking period, when sensorimotor calibrations are most intense. Theta band shifts from parietal to frontal cortices throughout tracking, likely reflecting a shift in the functional relevance from attentional sampling to action monitoring. This study shows that resource allocation mechanisms in prefrontal areas and stimulus-response mapping processes in the parietal cortex are crucial for adapting sensorimotor processes. It fills a knowledge gap in understanding the neural processes underlying action monitoring and suggests new directions for examining sensorimotor integration in more naturalistic experiments. [Abstract copyright: © 2023 The Author(s).
TRACK-a new algorithm and open-source tool for the analysis of pursuit-tracking sensorimotor integration processes.
In daily life, sensorimotor integration processes are fundamental for many cognitive operations. The pursuit-tracking paradigm is an ecological and valid paradigm to examine sensorimotor integration processes in a more complex environment than many established tasks that assess simple motor responses. However, the analysis of pursuit-tracking performance is complicated, and parameters quantified to examine performance are sometimes ambiguous regarding their interpretation. We introduce an open-source algorithm (TRACK) to calculate a new tracking error metric, the spatial error, based on the identification of the intended target position for the respective cursor position. The identification is based on assigning cursor and target direction changes to each other as key events, based on the assumptions of similarity and proximity. By applying our algorithm to pursuit-tracking data, beyond replication of known effects such as learning or practice effects, we show a higher precision of the spatial tracking error, i.e., it fits our behavioral data better than the temporal tracking error and thus provides new insights and parameters for the investigation of pursuit-tracking behavior. Our work provides an important step towards fully utilizing the potential of pursuit-tracking tasks for research on sensorimotor integration processes. [Abstract copyright: © 2023. The Author(s).
Induction of Epidermal Growth Factor Receptor Expression by Epstein-Barr Virus Latent Membrane Protein 1 C-Terminal-Activating Region 1 Is Mediated by NF- B p50 Homodimer/Bcl-3 Complexes
The Epstein-Barr virus (EBV) is associated with the development of numerous malignancies, including the epithelial malignancy nasopharyngeal carcinoma (NPC). The viral oncoprotein latent membrane protein 1 (LMP1) is expressed in almost all EBV-associated malignancies and has profound effects on gene expression. LMP1 acts as a constitutively active tumor necrosis factor receptor and activates multiple forms of the NF-κB family of transcription factors. LMP1 has two domains that both activate NF-κB. In epithelial cells, LMP1 C-terminal activating region 1 (CTAR1) uniquely activates p50/p50-, p50/p52-, and p65-containing complexes while CTAR2 activates canonical p50/p65 complexes. CTAR1 also uniquely upregulates the epidermal growth factor receptor (EGFR). In NPC, NF-κB p50/p50 homodimers and the transactivator Bcl-3 were detected on the EGFR promoter. In this study, the role of NF-κB p50 and Bcl-3 in LMP1-mediated upregulation of EGFR was analyzed. In LMP1-CTAR1-expressing cells, chromatin immunoprecipitation detected p50 and Bcl-3 on the NF-κB consensus sites within the egfr promoter. Transient overexpression of p50 and Bcl-3 increased EGFR expression, confirming the regulation of EGFR by these factors. Treatment with p105/p50 siRNA effectively reduced p105/p50 levels but unexpectedly increased Bcl-3 expression and levels of p50/Bcl-3 complexes, resulting in increased EGFR expression. These data suggest that induction of p50/p50/Bcl-3 complexes by LMP1 CTAR1 mediates LMP1-induced EGFR upregulation and that formation of the p50/p50/Bcl-3 complex is negatively regulated by the p105 precursor. The distinct forms of NF-κB that are induced by LMP1 CTAR1 likely activate distinct cellular genes
Multipole nonlinearity of metamaterials
We report on the linear and nonlinear optical response of metamaterials
evoked by first and second order multipoles. The analytical ground on which our
approach bases permits for new insights into the functionality of
metamaterials. For the sake of clarity we focus here on a key geometry, namely
the split-ring resonator, although the introduced formalism can be applied to
arbitrary structures. We derive the equations that describe linear and
nonlinear light propagation where special emphasis is put on second harmonic
generation. This contribution basically aims at stretching versatile and
existing concepts to describe light propagation in nonlinear media towards the
realm of metamaterials.Comment: 7 pages, 3 figure
- …