29 research outputs found
Reducing Crowding by Weakening Inhibitory Lateral Interactions in the Periphery with Perceptual Learning
We investigated whether lateral masking in the near-periphery, due to inhibitory lateral interactions at an early level of central visual processing, could be weakened by perceptual learning and whether learning transferred to an untrained, higher-level lateral masking known as crowding. The trained task was contrast detection of a Gabor target presented in the near periphery (4°) in the presence of co-oriented and co-aligned high contrast Gabor flankers, which featured different target-to-flankers separations along the vertical axis that varied from 2λ to 8λ. We found both suppressive and facilitatory lateral interactions at target-to-flankers distances (2λ - 4λ and 8λ, respectively) that were larger than those found in the fovea. Training reduces suppression but does not increase facilitation. Most importantly, we found that learning reduces crowding and improves contrast sensitivity, but has no effect on visual acuity (VA). These results suggest a different pattern of connectivity in the periphery with respect to the fovea as well as a different modulation of this connectivity via perceptual learning that not only reduces low-level lateral masking but also reduces crowding. These results have important implications for the rehabilitation of low-vision patients who must use peripheral vision to perform tasks, such as reading and refined figure-ground segmentation, which normal sighted subjects perform in the fovea
Anisotropic encoding of three-dimensional space by place cells and grid cells
The subjective sense of space may result in part from the combined activity of place cells in the hippocampus and grid cells in posterior cortical regions such as the entorhinal cortex and pre- and parasubiculum. In horizontal planar environments, place cells provide focal positional information, whereas grid cells supply odometric (distance measuring) information. How these cells operate in three dimensions is unknown, even though the real world is three-dimensional. We investigated this issue in rats exploring two different kinds of apparatus: a climbing wall (the 'pegboard') and a helix. Place and grid cell firing fields had normal horizontal characteristics but were elongated vertically, with grid fields forming stripes. It seems that grid cell odometry (and by implication path integration) is impaired or absent in the vertical domain, at least when the rat itself remains horizontal. These findings suggest that the mammalian encoding of three-dimensional space is anisotropic
Clinical and radiographic comparison of the effects of two types of fixed retainers on periodontium - A randomized clinical trial
Background: Most orthodontists believe that fixed retainers are necessary to maintain ideal dental relationships.
However, untoward side effects might result from their long-term placement. The aim of this study was to evaluate
the clinical and radiographic effect of two commonly used fixed retainers on the health of the periodontium.
Methods: Thirty patients were randomly divided into two groups to receive either a fiber-reinforced composite
retainer or a spiral wire retainer extended on the lingual surfaces of both maxillary and mandibular arches from
canine to canine. Periapical radiographs were obtained from the patients at the time of placement of the retainers
and after the 6-month period to assess the radiographic conditions of the periodontium. Clinical examination was
carried out at the same two time intervals.
Results: Even though there were no significant differences between the two groups of study at the beginning of
the trial, there were statistically significant differences after the 6-month follow-up regarding the main outcomes of
the study. Nearly all indices showed to deteriorate after 6 months in the fiber-reinforced group, while in the spiral
wire group, this was not the case. As for the secondary outcomes, radiographic examination did not reveal any
statistically significant differences after 6 months or between the two groups.
Conclusions: It can be concluded that spiral wire retainers elicit less detrimental periodontal response in the short-term
follow-up compared to fiber-reinforced composite retainers as revealed by the primary outcomes of the study