Increasing Ultrasound-Guided Thyroid Biopsy Yield

Objectives: Conduct Plan-Do-Study-Act (PDSA) performance improvement project to improve thyroid biopsy yield Short Term\u3ereduce unsuccessful biopsies by 50% Long-Term\u3eeliminate unsuccessful biopsieshttps://jdc.jefferson.edu/patientsafetyposters/1064/thumbnail.jp

Shedding Light on the Off-Hours Coverage Gap in Radiology: Improving Turnaround Times and Critical Results Reporting

Objective: Devise a plan to optimize off-hours faculty and trainee staffing within the Department of Radiology Measure the magnitude of patient safety gains in terms of report turnaround times (TAT) and critical results communication times (CRC)https://jdc.jefferson.edu/patientsafetyposters/1044/thumbnail.jp

Reading Room Assistance Pilot: Improving Radiologist Workflow

Aims for Improvement Our aim for improvement was to find ways to decrease distractions and phone calls in the body radiology reading room and to convert unpredictable and “immediate-response distractions” to “managed distractions” that can be addressed without aborting patient care/case interpretation immediately and unnecessarily. The goal was to decrease interruptions which would allow more time to be spent on reading cases, learning, and teaching. One metric that we identified was the number of phone calls to the reading room, which we intend to decrease by 50% within the first quarter. Another metric was the radiology attending and resident attitudes toward workflow and efficiency in the reading room. We intend to assess radiologist perception of the workflow environment and a decrease in distractions as measured by a survey administered before and after implementation. Additionally, we expect to improve efficiency and will compare productivity in terms of care delivered/cases reviewed

OncoLog Volume 45, Number 06, June 2000

Newly Organized Ophthalmology Section Expands Treatment of Ocular Malignancies Turning Knowledge Into Effective Gene Therapies, by Jack A. Roth, MD, Professor, Department of Thoracic and Cardiovascular Surgery, and Gary S. Clayman, MD, DDS, Associate Professor, Head and Neck Surgery Microarrays Reduce Time, Labor, and Cost of DNA Analysis New DNA Microarray Technology Could Speed Up Discovery of the Genetic Causes of Lung Cancer House Call: Virtual Health: Finding Reliable Medical Resources on the Internet Clinical Practice Guidelines: Case Report: Ovarian Cancer Protocols: Studies Aim to Detect and Treat Ocular Malignancieshttps://openworks.mdanderson.org/oncolog/1086/thumbnail.jp

OncoLog Volume 49, Number 06, June 2004

Despite Initial Setbacks, Researchers Are Focusing on Antiangiogenic Therapy More Than Ever Dynamic Contrast-Enhanced Magnetic Resonance Imaging Predicts Response to Antiangiogenesis Agents Smart Bombs : Targeted Therapies Home in on Increasingly Well-Defined Targets House Call: Understanding Angiogenesis DiaLog: Gene Therapy for Cancer: Safety First, by Jack Roth, MD, Chair, Department of Thoracic and Cardiovascular Surgeryhttps://openworks.mdanderson.org/oncolog/1130/thumbnail.jp

Cardiovascular Diseases in India Compared With the United States

This review describes trends in the burden of cardiovascular diseases (CVDs) and risk factors in India compared with the United States; provides potential explanations for these differences; and describes strategies to improve cardiovascular health behaviors, systems, and policies in India. The prevalence of CVD in India has risen over the past 2 decades due to population growth, aging, and a stable age-adjusted CVD mortality rate. Over the same time period, the United States has experienced an overall decline in age-adjusted CVD mortality, although the trend has begun to plateau. These improvements in CVD mortality in the United States are largely due to favorable population-level risk factor trends, specifically with regard to tobacco use, cholesterol, and blood pressure, although improvements in secondary prevention and acute care have also contributed. To realize similar gains in reducing premature death and disability from CVD, India needs to implement population-level policies while strengthening and integrating its local, regional, and national health systems. Achieving universal health coverage that includes financial risk protection should remain a goal to help all Indians realize their right to health

Realization of SOC behavior in a dc glow discharge plasma

Experimental observations consistent with Self Organized Criticality (SOC) have been obtained in the electrostatic floating potential fluctuations of a dc glow discharge plasma. Power spectrum exhibits a power law which is compatible with the requirement for SOC systems. Also the estimated value of the Hurst exponent (self similarity parameter), H being greater than 0.5, along with an algebraic decay of the autocorrelation function, indicate the presence of temporal long-range correlations, as may be expected from SOC dynamics. This type of observations in our opinion has been reported for the first time in a glow discharge system.Comment: Key Words: Glow discharge; Self Organized Criticality; Hurst exponent; R/S technique; Power spectrum; Autocorrelation function; Nongaussian probability distribution function. Phys Lett A (article in Press

The topology of a discussion: the #occupy case

We analyse a large sample of the Twitter activity developed around the social movement 'Occupy Wall Street' to study the complex interactions between the human communication activity and the semantic content of a discussion. We use a network approach based on the analysis of the bipartite graph @Users-#Hashtags and of its projections: the 'semantic network', whose nodes are hashtags, and the 'users interest network', whose nodes are users In the first instance, we find out that discussion topics (#hashtags) present a high heterogeneity, with the distinct role of the communication hubs where most the 'opinion traffic' passes through. In the second case, the self-organization process of users activity leads to the emergence of two classes of communicators: the 'professionals' and the 'amateurs'. Moreover the network presents a strong community structure, based on the differentiation of the semantic topics, and a high level of structural robustness when a certain set of topics are censored and/or accounts are removed. Analysing the characteristics the @Users-#Hashtags network we can distinguish three phases of the discussion about the movement. Each phase corresponds to specific moment of the movement: from declaration of intent, organisation and development and the final phase of political reactions. Each phase is characterised by the presence of specific #hashtags in the discussion. Keywords: Twitter, Network analysisComment: 13 pages, 9 figure

Systemic Sclerosis–Associated Interstitial Lung Disease: How to Incorporate Two Food and Drug Administration–Approved Therapies in Clinical Practice

Systemic sclerosis (SSc; scleroderma) has the highest individual mortality of all rheumatic diseases and interstitial lung disease (ILD) is among the leading causes of SSc-related death. Two drugs are now approved by the Food & Drug Administration (FDA) and indicated for slowing the rate of decline in pulmonary function in patients with SSc-ILD: nintedanib (a tyrosine kinase inhibitor) and tocilizumab (the first biologic agent targeting the interleukin-6 pathway in SSc). In addition, two generic drugs with cytotoxic and immunoregulatory activity, mycophenolate mofetil and cyclophosphamide, have shown comparable efficacy in a Phase II trial but are not FDA-approved for SSc-ILD. In light of the heterogeneity of the disease, the optimal therapeutic strategy in the management of patients with SSc-ILD is still to be determined. The objectives of this review are two-fold: (1) review the body of research focused on the diagnosis and treatment of SSc-ILD; and (2) propose a practical approach for diagnosis, stratification, management, and therapeutic decision-making in this clinical context. This review presents a practical classification of SSc patients in terms of disease severity (subclinical vs. clinical ILD) and associated risk of progression (low vs. high risk). The pharmacological and non-pharmacological options as first and second-line therapy, as well as potential combination approaches, are discussed in light of the recent approval of tocilizumab for SSc-ILD