3 research outputs found

    Mise au point d'une PCR quantitative de l'herpès virus humainde type 6 au laboratoire de virologie (intérêt dans le suivi des greffes de moelle osseuse)

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    Human herpesvirus 6 primary infection usually happens in the first two years of life. Most of the time, it is harmless with only high fever and more rarely cutaneous rash. HHV-6 remains latent in numerous cell types and may reactivate in immunocompromised patients, especially those who undergo bone marrow or peripheral stem cell transplantation. HHV-6 infection is often associated with delayed engraftment or bone marrow suppression. It may also play a role in the outbreak or exacerbation of graft versus host disease. During this work, we developped a quantitative HHV-6 real-time PCR on the LightCycler instrument. It may efficiently help in determining HHV-6 reactivation and appreciating the effectiveness of antiviral therapy. In case of HHV-6 related symptoms, viral load quantification in blood and biopsy samples appear to be helpful to assess reactivation.TOULOUSE3-BU Santé-Centrale (315552105) / SudocSudocFranceF

    Difference in partition noise for 1.55 μm quantum-dash and bulk structures

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    International audienceThe comparison of relative intensity noise (Rin) shows improved performances, for quantum dash laser (QD) compared to the ones of bulk medium structures. We introduced a statistical measurement through a coupling parameter that reveals the impact of strong damping on the competition between modes or the so-called partition noise. The existence of a strong damping in QD laser prevents the relaxation frequency from being observed in the coupling parameter, which makes the noise to appear as if the laser lines were inhomogeneous. However the method also enables the characterization of the coupling strength between modes, showing again differences between QD and bulk structures
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