8 research outputs found
Malaria and obesity: obese mice are resistant to cerebral malaria
- Author
- A Ariyasinghe
- AA Lamikanra
- ALL Neill
- AM Prentice
- B Genton
- B Meister
- Catherine Bourgouin
- Catherine Thouvenot
- CP Liang
- Delphine Depoix
- F Lonnqvist
- G Matarese
- GM Lord
- H Lan
- HC van der Heyde
- J Lou
- JB De Souza
- JL Deen
- K Elased
- K Elased
- KM Elased
- KM Elased
- KM Elased
- M Moumaris
- M Pulido-Mendez
- M Tanner
- Marie-Noëlle Lombard
- MC Mbago
- ME Onwuamaegbu
- MN Lombard
- N Takahashi
- NF Delahaye
- NF Delahaye
- O Shalev
- P Amuna
- P Sinnis
- Philippe Grellier
- PU Dubuc
- RA Memon
- RG Hendrickse
- RM Tarsi
- T Gainsford
- UE Schaible
- Vincent Robert
- Publication venue
- BioMed Central
- Publication date
- 01/01/2008
- Field of study
This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens
An Overview of Randomized Algorithms
- Author
- A Blum
- A Schrijver
- A Sinclair
- AB Borodin
- CAR Hoare
- D Coppersmith
- DJA Welsh
- DR Karger
- DR Karger
- F Maffioli
- J Edmonds
- J.T. Schwartz
- JE Hoperoft
- K Mulmuley
- K Mulmuley
- L Lovâsz
- LG Valiant
- M Blum
- M Saks
- M Snir
- M Tarsi
- MO Rabin
- MO Rabin
- MO Rabin
- R Aleliunas
- R Freivalds
- R Motwani
- R Motwani
- R Solovay
- RA Demillo
- RE Zippel
- RG Seidel
- RM Karp
- RM Karp
- RM Karp
- RW Floyd
- S Ben-David
- S Micali
- VV Vazirani
- W Pugh
- WT Tutte
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1998
- Field of study
The population history of the Croatian linguistic minority of Molise (southern Italy): a maternal view
- Author
- A Helgason
- A Sajantila
- A Sujoldžić
- A Sujoldžić
- A Tagliabracci
- Anita Sujoldžić
- AT Smith
- BA Malyarchuk
- BA Malyarchuk
- Branka Janićijević
- C Herrnstadt
- Carla Babalini
- Cristina MartĂnez-Labarga
- D Gresham
- F Tajima
- G Biondi
- G Scotti
- Gianfranco Biondi
- H-V Tolk
- H-V Tolk
- HC Harpending
- Helle-Viivi Tolk
- HJ Bandelt
- I Dupanloup
- Irena Martinović Klarić
- Irene Contini
- J Bertranpetit
- J Reynolds
- JA Wilder
- JB Kruskal
- JM Larruga
- L Excoffier
- LB Jorde
- Lovorka Barać
- M Belledi
- M Nei
- M Richards
- M Richards
- M Slatkin
- M Stoneking
- Marijana Peričić
- MI Seielstad
- N Maca-Meyer
- O Rickards
- O Rickards
- O Rickards
- Olga Rickards
- Pavao Rudan
- Richard Villems
- Rita Giampaolo
- RM Andrews
- S Anderson
- S Plaza
- S Salvi
- SA Miller
- Tiziana Tarsi
- Toomas Kivisild
- V Macaulay
- Z Brakez
- Publication venue
- European Society of Human Genetics, Nature
- Publication date
- 01/01/2005
- Field of study
This study examines the mitochondrial DNA (mtDNA) diversity of the Croatian-speaking minority of Molise and evaluates its potential genetic relatedness to the neighbouring Italian groups and the Croatian parental population. Intermatch, genetic distance, and admixture analyses highlighted the genetic similarity between the Croatians of Molise and the neighbouring Italian populations and demonstrated that the Croatian-Italian ethnic minority presents features lying between Croatians and Italians. This finding was confirmed by a phylogeographic approach which revealed both the prevalence of Croatian and the penetrance of Italian maternal lineages in the Croatian community of Molise. These results suggest that there was no reproductive isolation between the two geographically proximate, yet culturally distinct populations living in Italy. The gene flow between the Croatian-Italians and the surrounding Italian populations indicate, therefore, that ethnic consciousness has not created reproductive barriers and that the Croatian-speaking minority of Molise does not represent a reproductively isolated entity
The population history of the Croatian linguistic minority of Molise (southern Italy): a maternal view
- Author
- A Helgason
- A Sajantila
- A Sujoldžić
- A Sujoldžić
- A Tagliabracci
- Anita Sujoldžić
- AT Smith
- BA Malyarchuk
- BA Malyarchuk
- Branka Janićijević
- C Herrnstadt
- Carla Babalini
- Cristina MartĂnez-Labarga
- D Gresham
- F Tajima
- G Biondi
- G Scotti
- Gianfranco Biondi
- H-V Tolk
- H-V Tolk
- HC Harpending
- Helle-Viivi Tolk
- HJ Bandelt
- I Dupanloup
- Irena Martinović Klarić
- Irene Contini
- J Bertranpetit
- J Reynolds
- JA Wilder
- JB Kruskal
- JM Larruga
- L Excoffier
- LB Jorde
- Lovorka Barać
- M Belledi
- M Nei
- M Richards
- M Richards
- M Slatkin
- M Stoneking
- Marijana Peričić
- MI Seielstad
- N Maca-Meyer
- O Rickards
- O Rickards
- O Rickards
- Olga Rickards
- Pavao Rudan
- Richard Villems
- Rita Giampaolo
- RM Andrews
- S Anderson
- S Plaza
- S Salvi
- SA Miller
- Tiziana Tarsi
- Toomas Kivisild
- V Macaulay
- Z Brakez
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Natural Products in Caries Research: Current (Limited) Knowledge, Challenges and Future Perspective
- Author
- Aires CP
- Allaker RP
- Almas K
- Axelsson P
- Bae K
- Bakkali F
- Bakri IM
- Banas JA
- Bankova V
- Beighton D
- Bennick A
- Bowen WH
- Bowen WH
- Bowen WH
- Brecx M
- Brighenti FL
- Busscher HJ
- Cai S
- Castro ML
- Castro ML
- Cheng L
- Choi BK
- Clardy J
- Cowan MM
- Cross SE
- Darout IA
- Duarte S
- Duarte S
- Dye BA
- Dzink JL
- DĂĽrig A
- Eley BM
- Fontana M
- Fujiwara M
- Furiga A
- Godowski KC
- Greenberg M
- Gregoire S
- Groppo FC
- Groppo FC
- Guggenheim B
- Gunatilaka AAL
- H. Koo
- Hamada S
- Hamilton-Miller JM
- Hammer KA
- Hattori M
- Hayacibara MF
- Hayashi Y
- Hirasawa M
- Hirasawa M
- Hoover JN
- Ikeno K
- Inoue Y
- Islam B
- Islam B
- J.-G. Jeon
- Jagtap AG
- Jeon JG
- Koehn FE
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Koo H
- Kopec LK
- Lemos JA
- Lemos JA
- Li XC
- Linke HA
- Loesche WJ
- Loesche WJ
- M.L. Falsetta
- Marquis RE
- Marsh PD
- Marsh PD
- Matsumoto M
- Matsumoto M
- Matsumoto M
- McCabe RM
- Menezes SMS
- Murata RM
- Nakahara K
- Newman DJ
- Ooshima T
- Ooshima T
- Ooshima T
- Ooshima T
- Osawa K
- Otake S
- P.L. Rosalen
- Paes Leme AF
- Pai MR
- Park YK
- Park YK
- Quivey
- Rasooli I
- Rosen S
- Rölla G
- Saeki Y
- Sakanaka S
- Salatino A
- Sasaki H
- Sato S
- Scheie AA
- Schilling KM
- Schilling KM
- Schmidt BM
- Sforcin JM
- Shapiro S
- Shapiro S
- Shinada K
- Shouji N
- Silva BB
- Singer AC
- Song JH
- Spatafora G
- Steinberg D
- Stookey GK
- Tagashira M
- Takarada K
- Tamesada M
- Tang G
- Tanzer JM
- Tarsi R
- Touyz LZ
- Twetman S
- Vacca-Smith AM
- van Loveren C
- Venkitaraman AR
- Verpoorte R
- Vogel JJ
- Wen D
- Wolinsky LE
- Wolinsky LE
- Wong L
- Wu KM
- Wu-Yuan CD
- Wunder D
- Xiao J
- Xie Q
- Yamanaka A
- Yamashita Y
- Yanagida A
- Zero DT
- Publication venue
- 'S. Karger AG'
- Publication date
- 01/01/2011
- Field of study
Engineering Blood-Contact Biomaterials by “H-Bond Grafting” Surface Modification
- Author
- A Podias
- A Remes
- A Takahara
- A Varki
- AA Spector
- AB Anderson
- AF Von Recum
- AH Zisch
- AS Hoffman
- AS Sawhney
- AW Clowes
- BD Ratner
- BE Jarrell
- BK Mann
- BK Mann
- BK Mann
- BL Cameron
- BS Coller
- C Freij-Larsson
- C Gosselin
- C Marco
- C Nojiri
- CA Buck
- CC Tsai
- CL Haycox
- CL Martins
- CL Martins
- CT Esmon
- D Seliktar
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DA Wang
- DD Lasic
- DE Chenoweth
- DE Gregonis
- DF Williams
- DK Han
- DS Goodman
- E Osterberg
- E Uchida
- EF Plow
- EJ Castillo
- EL Chaikof
- EW Merrill
- G Voskerician
- GM O'Shea
- GP Lopez
- GP Lopez
- GR Llanos
- GS Ferguson
- GT Hermanson
- H Kobayashi
- H Kobayashi
- H Magometschnigg
- HP Greisler
- I Noh
- J Cui
- J Guan
- J Guan
- J Guan
- J Guan
- J Ji
- J Ji
- J Ji
- J March
- JA Chinn
- JA Hubbell
- JA Hubbell
- JD Andrade
- JD Patel
- JE Sanders
- JG Terlingen
- JH Beer
- JH Silver
- JJ Stankus
- JJ Stankus
- JL Brash
- JL Gray
- JR Gamble
- JR Keogh
- JR Keogh
- JR Keogh
- JS Jeon
- JS Jeon
- JW Boretos
- K Fujimoto
- K Ishihara
- K Ishihara
- K Ishihara
- K Ishihara
- K Kojima
- K Ohta
- K Ohta
- KA Robinson
- KD Park
- KG Tingey
- KK Chittur
- KL Prime
- KM Yamada
- LA Lasky
- LJ Suggs
- LM Graham
- LR Sauvage
- M Amiji
- M Makino
- M Morimoto
- M Nomizu
- M Pierschbacher
- M Uchida
- M Yan
- MA Harthcock
- MD Lelah
- MH Fittkau
- MM Coleman
- MR Brunstedt
- MR Brunstedt
- NA Peppas
- NL Burns
- NM Helmus
- NP Desai
- NP Desai
- P Jannasch
- P Jannasch
- P Wojciechowski
- P Zilla
- PA Dimilla
- PA Hardhammar
- PM Triolo
- PW Serruys
- R Guidoin
- R Langer
- R Tarsi
- RD Schaub
- RH Schmedlen
- RJ Leatherbarrow
- RJ Levy
- RM McCormick
- RO Hynes
- RW Snyder
- S Minami
- SA Barenberg
- SB Rao
- SC Yoon
- SD Drumheller
- SJ Sullivan
- SP Massia
- SQ Liu
- SR Stauffer
- SS Kang
- T Furuzono
- T Shimizu
- T Ueda
- TA Horbett
- TG Grasel
- TG Grasel
- TJ Lenk
- TL Kuhl
- WG Pitt
- WG Pitt
- WG Pitt
- WM Elbjeirami
- WR Gombotz
- Y Ikada
- Y Suzuki
- YB Aldenhoff
- YC Tseng
- Z Werb
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Ezetimibe added to statin therapy after acute coronary syndromes
- Author
- Aagnes I
- Aambakk MB
- Aase O
- Aaser E
- Abdel-Latief A
- Abell T
- Aboufakher R
- Abramson B
- Abrantes J
- Achilli A
- Adams A
- Adams K
- Adamus J
- Addington J
- Adgey A
- Adjei A
- Agarwal J
- Aggarwal A
- Aggarwal K
- Aggarwal R
- Agocha A
- Agraou B
- Aguirre O
- Ahmed A
- Ahmed O
- Ahsan A
- Airaksinen J
- Airoldi F
- Aji J
- Akkad H
- Akubzanova E
- Al-Ani R
- Al-Jumaily J
- Alameda J
- Albirini A
- Albuquerque A
- Albuquerque D
- Alcasena S
- Alexander J
- Alfonso F
- Ali MI
- Alings MA
- Allall O
- Allen J
- Allen RP
- Allred S
- Almeira AS
- Alonso L
- Alsagheer S
- Alshaher M
- Altschuller A
- Alvarez J
- Alvarez J
- Alvarez Y
- Alves A
- Amidon T
- Amos M
- Anaszewicz M
- Andersen M
- Andersen O
- Andersson E
- Andersson G
- Andrade G
- Andrade M
- Andrea B
- Andreou C
- Antonangelo A
- Antorrena I
- Appel K
- Arana C
- Aranda M
- Araujo J
- Arce R
- Ardito RV
- Ardito W
- Arend C
- Arias V
- Armada E
- Armstrong P
- Arnold A
- Arnold M
- Arntsen BI
- Arora P
- Aros F
- Arriagada G
- Arriagada G
- Artaecheverria J
- Arvesen K
- Arvigo L
- Ash Y
- Aske R
- Ata N
- Atar D
- Atar S
- Atassi K
- Atieh M
- Atkinson C
- Atzenhofer-Baumgartner K
- Auer J
- Aug L
- Ausen K
- Aycock G
- Aylward P
- Aylward P
- Ayres T
- Azize G
- Azrin M
- Azzolini P
- Babu R
- Bach R
- Badings EA
- Baeza N
- Baig M
- Baiz A
- Bajcsi É
- Balaguera J
- Balcells E
- Baldari D
- Baldus S
- Bali H
- Ballantyne C
- Ballmer P
- Banerjee S
- Bang-Hansen T
- Banikova A
- Bankowski D
- Banks K
- Bansal M
- Baraona F
- Barber C
- Barber C
- Barbir M
- Barillas O
- Barnes D
- Barnett O
- Barr C
- Barrett J
- Barringhaus K
- Barron M
- Bartels GL
- Basilio E
- Bass M
- Bassand J
- Bassand JP
- Bassand JP
- Basso V
- Bata I
- Battikadi S
- Battin D
- Bauer B
- Baumanns S
- Bautista J
- Bayat J
- Bayer M
- Bayer M
- Bayles A
- Bazzi A
- Beaudry M
- Bedoya R
- Been M
- Belicova M
- Bell K
- Belle L
- Beloscar J
- Beltran R
- Beltrano MC
- Ben-Aharon J
- Ben-Yehuda O
- Benetar J
- Bengtsson PO
- Bennermo M
- Bennett J
- Benyahya L
- Beresford P
- Berezniakov I
- Berger M
- Berger-Kucza A
- Bergeron J
- Berglund M
- Berglund R
- Bergsten J
- Berk M
- Berli M
- Bernardi D
- Berra F
- Berrospi P
- Bertolet B
- Bescos L
- Bethea C
- Bethencourt A
- Betti I
- Betzu R
- Bhalla H
- Bhalodkar N
- Bhargava M
- Bhargava R
- Bhargavi M
- Bhesania T
- Biasucci L
- Biedermann B
- Bikkina M
- Bilazarian S
- Bilodeau N
- Bin Ismail O
- Binaghi G
- Birkemeyer R
- Birnbaum Y
- Bishop A
- Bishop B
- Bishop C
- Bissett J
- Bissett J
- Bittel B
- Bitzer V
- Bjornstad H
- Blacher MG
- Blais D
- Blank E
- Blazing M
- Blazing M
- Blazing M
- Blazing Michael A.
- Blessing E
- Block D
- Bluguermann J
- Blumberg E
- Bobek M
- Bocconcelli P
- Bocconcelli P
- Bodanese L
- Bodenstein W
- Boehm S
- Bogomolny N
- Bohle D
- Bohlscheid V
- Bohorquez R
- Bohula Erin A.
- Boliek W
- Bolli R
- Bolsman C
- Bonatti S
- Bondi L
- Bondio M
- Bone C
- Bonnet J
- Bono J
- Book K
- Boomer L
- Boos C
- Botero R
- Bottzauw J
- Botwin S
- Boudriot E
- Bouvier JM
- Bowden W
- Bozek B
- Bradford L
- Bradford L
- Brady A
- Brady A
- Brady A
- Braga J
- Branca G
- Branny M
- Branzi A
- Braun P
- Braunwald Eugene
- Breen J
- Brike C
- Britto F
- Britto F
- Britto F
- Broadwater S
- Bronnum-Schou J
- Brossoit R
- Brown C
- Brown C
- Brown C
- Brown J
- Brunelli C
- Brunelli C
- Brunk S
- Bruno N
- Brunvand H
- Brussee H
- Bryniarski L
- Budzon S
- Bueno M
- Buerke M
- Buerke M
- Bugos V
- Buijs EM
- Buijs F
- Bullivant M
- Burgess L
- Burghard S
- Burley T
- Burton J
- Buss I
- Bustamante G
- Butcher R
- Butkus E
- Butter C
- Buzetti C
- Byfuglien A
- Cabrera-Santamaria A
- CalderĂłn MJ
- Calic S
- Califf
- Calpar I
- Calzolari D
- Campbell C
- Campbell T
- Campos C
- Cannon C
- Cannon C
- Cannon Christopher P.
- Canto J
- Cappelen H
- Capucci A
- Capucci A
- Cardillo MT
- Cardinal F
- Cardoso A
- Carell E
- Carell E
- Carey C
- Carlessi C
- Carlevaro O
- Carling-Chambers L
- Carlsson F
- Carmelo M
- Carr K
- Carrageta M
- Carrageta M
- Carrageta M
- Carrié D
- Carswell BS
- Cartasegna L
- Caruso O
- Casalins M
- Casares G
- Caso P
- Caspi A
- Cassadonte F
- Cassavar D
- Cassel G
- Castoldi M
- Castro P
- Castro R
- Catarino C
- Caussin C
- Cauthren T
- Cavallini C
- Ceder-Brolin K
- Centeno E
- Centurion C
- Cepeda M
- Cequier A
- Chadwyn D
- Chae SC
- Chalavarya G
- Chambers J
- Chandler G
- Chandna H
- Chandna H
- Chandna H
- Chandra P
- Chandraratna P
- Chandrasekaran S
- Chang D
- Chang G
- Chang K
- Chang K
- Chang M
- Charng M
- Chattree K
- Chavarri M
- Chavez V
- Chee K
- Chernick R
- Chessa P
- Cheung S
- Chew D
- Chhabra A
- Chian-Yi W
- Chiariello M
- Chilakamarri V
- Childs A
- Childs C
- Chiodi L
- Chiu A
- Cho M
- Choi Y
- Cholewa M
- Chopra A
- Chopra V
- Christopher J
- Christy L
- Chronos N
- Chu A
- Chui K
- Chung W
- Ciampricotti R
- Cianflone D
- Cicia G
- Cihalik C
- Ciliberti D
- Cirillo W
- Ciuti G
- Cizinsky S
- Clarke A
- Clarus S
- Clausen H
- Clausen H
- Clavero X
- Clemmensen P
- Cleveland D
- Cleveland T
- Cloud B
- Cobos M
- Cocco N
- Coelho O
- Coetzee C
- Coffin N
- Coffman A
- Cohen B
- Cohen LE
- Cohen Y
- Coisne D
- Coldwell J
- Colfer H
- Collins J
- Collins J
- Collins T
- Colombo H
- Commerford P
- Conaway D
- Connolly T
- Constance C
- Conti M
- Cooke J
- Cooke L
- Corbalan R
- Corbalan R
- Corbett C
- Cortada J
- Corut S
- Cossett J
- Costa M
- Costantini C
- Costello T
- Cottin Y
- Coviaux F
- Coy K
- Craig M
- Crandall L
- Crawford K
- Cristaldi J
- Cristell N
- Cronje T
- Cross D
- Crutchfield B
- Cryderman C
- CsapĂł K
- Cubeddu L
- Cuccia C
- Cullen T
- Curry R
- Curtis S
- Cush S
- Cusimano S
- Cyncar R
- D'Urso M
- da Costa FA
- da Cunha C
- Dagefoerde N
- Dahiya R
- Dalby A
- Dalby A
- Dalby A
- Dale H
- Daley P
- Dalin L
- Dambrine P
- Damiano M
- Damiano S
- Damm T
- Dani S
- Daniel D
- Daniels MC
- Danse IY
- Darcel I
- Darius H
- Darius H
- Darius H
- Darius Harald
- Darnell Z
- Dauber I
- Dave R
- David M
- Davidovits S
- Davidson L
- Davis B
- Davis C
- Davis G
- Davis T
- Davis W
- Davy J
- Dawson G
- De Andrade M
- De Belder M
- de Carvalho Moreira R
- De Caterina R
- De Clippel M
- De Feo S
- De Ferrari G
- De Ferrari G
- De Ferrari Gaetano M.
- De Ferrari GM
- De Gregorio M
- de la Guia F
- de la Guia F
- De Larochelliere R
- de Lemos J
- De Lemos J
- De Lucca Paul
- De Maria E
- de Sa E
- de Salazar D
- de Souza J
- de Teresa E
- de Valdecilla H
- De Velder L
- De Wolf L
- Debrouwer K
- Decker S
- DeFranco A
- Del Core M
- del Rio A
- Dela Cruz C
- Delahaye F
- Delgado J
- Delio-Cox B
- Della Siega A
- Dellatorre M
- Dellborg M
- Dellborg M
- Dellborg M
- Delport E
- Demarcq JM
- Dempsey K
- Den Hartog FR
- DeRaad R
- Desai V
- Desalca M
- DeSimone L
- DeVault S
- Devlin G
- Dhooghe G
- Di Biase M
- Di Fazio J
- Di Pasquale G
- Diadema B
- Dias D
- Dickinson D
- Dietz S
- Dietz W
- Diffenback M
- Dignen K
- Dijkshoorn-Giesen AH
- Dimenna J
- Diogo A
- Dion D
- Dionisopoulos P
- Dirkali A
- DiVito P
- Dobies D
- Dodt K
- Doerr M
- Dohmann H
- Dohmann H
- Domingo D
- Donegan R
- Donnelly B
- Donovan C
- Dos Santos ES
- Dos Santos LB
- Doty W
- Doucet M
- Doughty A
- Douglas L
- Dourmap-Collas C
- Doux N
- Dragu R
- Drenning D
- Drexel H
- Droste HT
- Duarte YC
- Dubiel J
- Dubois-Rande JL
- Duda N
- Duengen H
- Dujardin J
- Dujardin K
- Dunselman PH
- Dupuis R
- Duris T
- Duris T
- Duris T
- Duronto E
- Dussaubat A
- Dutra O
- Dwenger E
- Dzupina A
- Eaton C
- Eaton C
- Eaton G
- Ebelt H
- Eber B
- Ebrahim I
- Ebrahimi R
- Effat M
- Effron B
- Egger F
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- Wohns D
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- Yildiz Z
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- Yoon M
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- Zanini R
- Zanini R
- Zanolin D
- Zapata M
- Zarandon R
- Zeiher A
- Zeltser D
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- Zemberova A
- Zemour G
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- Zimlichman R
- Zimmerman T
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- Zingarelli A
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- Zucchetti C
- Zughaib M
- Zuidgeest JA
- Zuppiroli A
- Zwart PA
- Zweiker R
- Ă…ngman K
- Édes I
- Ă–stberg S
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2015
- Field of study
BACKGROUND: Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal cholesterol absorption, can reduce the rate of cardiovascular events further is not known. METHODS: We conducted a double-blind, randomized trial involving 18,144 patients who had been hospitalized for an acute coronary syndrome within the preceding 10 days and had LDL cholesterol levels of 50 to 100 mg per deciliter (1.3 to 2.6 mmol per liter) if they were receiving lipid-lowering therapy or 50 to 125 mg per deciliter (1.3 to 3.2 mmol per liter) if they were not receiving lipid-lowering therapy. The combination of simvastatin (40 mg) and ezetimibe (10 mg) (simvastatin-ezetimibe) was compared with simvastatin (40 mg) and placebo (simvastatin monotherapy). The primary end point was a composite of cardiovascular death, nonfatal myocardial infarction, unstable angina requiring rehospitalization, coronary revascularization ( 6530 days after randomization), or nonfatal stroke. The median follow-up was 6 years. RESULTS: The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin-ezetimibe group, as compared with 69.5 mg per deciliter (1.8 mmol per liter) in the simvastatin-monotherapy group (P<0.001). The Kaplan-Meier event rate for the primary end point at 7 years was 32.7% in the simvastatin-ezetimibe group, as compared with 34.7% in the simvastatin-monotherapy group (absolute risk difference, 2.0 percentage points; hazard ratio, 0.936; 95% confidence interval, 0.89 to 0.99; P = 0.016). Rates of pre-specified muscle, gallbladder, and hepatic adverse effects and cancer were similar in the two groups. CONCLUSIONS: When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit
The Famlily Vibrionaceae
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- A Böck
- A Camilli
- A Can-Gomez
- A Coelho
- A Coelho
- A Dalsgaard
- A Dalsgaard
- A Dalsgaard
- A Dalsgaard
- A Dalsgaard
- A DePaola
- A DePaola
- A DePaola
- A DePaola
- A Fabris
- A Hjelm Mette
- A Huq
- A HĂĽlsmann
- A Lacoste
- A Lozano-Leon
- A Luna-Gonzalez
- A Molina-Aja
- A Mukherji
- A Naka
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- A Roque
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- AF Andersson
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- AJ Haugo
- AJ Silva
- AK Mukhopadhyay
- AL Furniss
- AM Carnahan
- AS Kreger
- AS Schmidt
- ASS Hameed
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- B Allam
- B Austin
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- B Chang
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- M Love
- M Miyake
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- M Muniesa-Perez
- M Nishibuchi
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- T Aoki
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- T Kaneko
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