3,206 research outputs found
Transcriptome analysis of Brachypodium during fungal pathogen infection reveals both shared and distinct defense responses with wheat
© 2017 The Author(s). Fusarium crown rot (FCR) of wheat and barley, predominantly caused by the fungal pathogen Fusarium pseudograminearum, is a disease of economic significance. The quantitative nature of FCR resistance within cultivated wheat germplasm has significantly limited breeding efforts to enhanced FCR resistance in wheat. In this study, we characterized the molecular responses of Brachypodium distachyon (Brachypodium hereafter) to F. pseudograminearum infection using RNA-seq to determine whether Brachypodium can be exploited as a model system towards better understanding of F. pseudograminearum-wheat interaction. The transcriptional response to infection in Brachypodium was strikingly similar to that previously reported in wheat, both in shared expression patterns of wheat homologs of Brachypodium genes and functional overlap revealed through comparative gene ontology analysis in both species. Metabolites produced by various biosynthetic pathways induced in both wheat and Brachypodium were quantified, revealing a high degree of overlap between these two species in metabolic response to infection but also showed Brachypodium does not produce certain defence-related metabolites found in wheat. Functional analyses of candidate genes identified in this study will improve our understanding of resistance mechanisms and may lead to the development of new strategies to protect cereal crops from pathogen infection
Model prediction of subendocardial perfusion of the coronary circulation in the presence of an epicardial coronary artery stenosis
The subendocardium is most vulnerable to ischemia, which is ameliorated by relaxation during diastole and increased coronary pressure. Recent clinical techniques permit the measuring of subendocardial perfusion and it is therefore important to gain insight into how measurements depend on perfusion conditions of the heart. Using data from microsphere experiments a layered model of the myocardial wall was developed. Myocardial perfusion distribution during hyperemia was predicted for different degrees of coronary stenosis and at different levels of Diastolic Time Fraction (DTF). At the reference DTF, perfusion was rather evenly distributed over the layers and the effect of the stenosis was homogenous. However, at shorter or longer DTF, the subendocardium was the first or last to suffer from shortage of perfusion. It is therefore concluded that the possible occurrence of subendocardial ischemia at exercise is underestimated when heart rate is increased and DTF is lower
Emotion based attentional priority for storage in visual short-term memory
A plethora of research demonstrates that the processing of emotional faces is prioritised over non-emotive stimuli when cognitive resources are limited (this is known as ‘emotional superiority’). However, there is debate as to whether competition for processing resources results in emotional superiority per se, or more specifically, threat superiority. Therefore, to investigate prioritisation of emotional stimuli for storage in visual short-term memory (VSTM), we devised an original VSTM report procedure using schematic (angry, happy, neutral) faces in which processing competition was manipulated. In Experiment 1, display exposure time was manipulated to create competition between stimuli. Participants (n = 20) had to recall a probed stimulus from a set size of four under high (150 ms array exposure duration) and low (400 ms array exposure duration) perceptual processing competition. For the high competition condition (i.e. 150 ms exposure), results revealed an emotional superiority effect per se. In Experiment 2 (n = 20), we increased competition by manipulating set size (three versus five stimuli), whilst maintaining a constrained array exposure duration of 150 ms. Here, for the five-stimulus set size (i.e. maximal competition) only threat superiority emerged. These findings demonstrate attentional prioritisation for storage in VSTM for emotional faces. We argue that task demands modulated the availability of processing resources and consequently the relative magnitude of the emotional/threat superiority effect, with only threatening stimuli prioritised for storage in VSTM under more demanding processing conditions. Our results are discussed in light of models and theories of visual selection, and not only combine the two strands of research (i.e. visual selection and emotion), but highlight a critical factor in the processing of emotional stimuli is availability of processing resources, which is further constrained by task demands
Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins
Velocity field measurements of cavitating flows
A particle Image Velocimetry (PIV) system has been developed to study the microfluid mechanics of cavitating flows. Planar PIV was used to examine the non-cavitating flow in the thin boundary layer near a hydrofoil surface for the cases of a naturally developing boundary layer and a boundary layer stimulated to turbulence by roughness near the foil leading edge. PIV was also used to examine the flow near the surface of individual cavitation bubbles and incipient attached cavitation. A system was devised to create a single nucleus in the flow upstream of a hydrofoil, and planar PIV was used to study the flow around the resulting traveling cavitation bubble. Velocity vectors were determined close to the solid surfaces and the gas/liquid interfaces of the bubbles. Seeding of the flow with particles did not result in the addition of active cavitation nuclei.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47070/1/348_2004_Article_BF00189302.pd
Electric-field-induced coherent coupling of the exciton states in a single quantum dot
The signature of coherent coupling between two quantum states is an
anticrossing in their energies as one is swept through the other. In single
semiconductor quantum dots containing an electron-hole pair the eigenstates
form a two-level system that can be used to demonstrate quantum effects in the
solid state, but in all previous work these states were independent. Here we
describe a technique to control the energetic splitting of these states using a
vertical electric field, facilitating the observation of coherent coupling
between them. Near the minimum splitting the eigenstates rotate in the plane of
the sample, being orientated at 45{\deg} when the splitting is smallest. Using
this system we show direct control over the exciton states in one quantum dot,
leading to the generation of entangled photon pairs
Qubit portrait of the photon-number tomogram and separability of two-mode light states
In view of the photon-number tomograms of two-mode light states, using the
qubit-portrait method for studying the probability distributions with infinite
outputs, the separability and entanglement detection of the states are studied.
Examples of entangled Gaussian state and Schr\"{o}dinger cat state are
discussed.Comment: 20 pages, 6 figures, TeX file, to appear in Journal of Russian Laser
Researc
Unpacking the relationships between impulsivity, neighborhood disadvantage, and adolescent violence : an application of a neighborhood-based group decomposition
The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007–2013)/ERC Grant Agreement no. 615159 (ERC Consolidator Grant DEPRIVEDHOODS, Socio-spatial inequality, deprived neighbourhoods, and neighbourhood effects); and from the Marie Curie programme under the European Union’s Seventh Framework Programme (FP/2007–2013)/Career Integration Grant no. PCIG10-GA-2011-303728 (CIG Grant NBHCHOICE, Neighbourhood choice, neighbourhood sorting, and neighbourhood effects).Scholars have become increasingly interested in how social environments condition the relationships between individual risk-factors and adolescent behavior. An appreciable portion of this literature is concerned with the relationship between impulsivity and delinquency across neighborhood settings. The present article builds upon this growing body of research by considering the more nuanced pathways through which neighborhood disadvantage shapes the development of impulsivity and provides a situational context for impulsive tendencies to manifest in violent and aggressive behaviors. Using a sample of 12,935 adolescent from the National Longitudinal Study of Adolescent to Adult Health (Add Health) (mean age = 15.3, 51% female; 20% Black, 17% Hispanic), we demonstrate the extent to which variation in the association between impulsivity and delinquency across neighborhoods can be attributed to (1) differences in mean-levels of impulsivity and violence and (2) differences in coefficients across neighborhoods. The results of a series of multivariate regression models indicate that impulsivity is positively associated with self-reported violence, and that this relationship is strongest among youth living in disadvantaged neighborhoods. The moderating effect of neighborhood disadvantage can be attributed primarily to the stronger effect of impulsivity on violence in these areas, while differences in average levels of violence and impulsivity account for a smaller, yet nontrivial portion of the observed relationship. These results indicate that the differential effect of impulsivity on violence can be attributed to both developmental processes that lead to the greater concentration of violent and impulsive adolescents in economically deprived neighborhoods as well as the greater likelihood of impulsive adolescents engaging in violence when they reside in economically disadvantaged communities.Publisher PDFPeer reviewe
MuSR method and tomographic probability representation of spin states
Muon spin rotation/relaxation/resonance (MuSR) technique for studying matter
structures is considered by means of a recently introduced probability
representation of quantum spin states. A relation between experimental MuSR
histograms and muon spin tomograms is established. Time evolution of muonium,
anomalous muonium, and a muonium-like system is studied in the tomographic
representation. Entanglement phenomenon of a bipartite muon-electron system is
investigated via tomographic analogues of Bell number and positive partial
transpose (PPT) criterion. Reconstruction of the muon-electron spin state as
well as the total spin tomography of composed system is discussed.Comment: 20 pages, 4 figures, LaTeX, submitted to Journal of Russian Laser
Researc
Symmetric informationally complete positive operator valued measure and probability representation of quantum mechanics
Symmetric informationally complete positive operator valued measures
(SIC-POVMs) are studied within the framework of the probability representation
of quantum mechanics. A SIC-POVM is shown to be a special case of the
probability representation. The problem of SIC-POVM existence is formulated in
terms of symbols of operators associated with a star-product quantization
scheme. We show that SIC-POVMs (if they do exist) must obey general rules of
the star product, and, starting from this fact, we derive new relations on
SIC-projectors. The case of qubits is considered in detail, in particular, the
relation between the SIC probability representation and other probability
representations is established, the connection with mutually unbiased bases is
discussed, and comments to the Lie algebraic structure of SIC-POVMs are
presented.Comment: 22 pages, 1 figure, LaTeX, partially presented at the Workshop
"Nonlinearity and Coherence in Classical and Quantum Systems" held at the
University "Federico II" in Naples, Italy on December 4, 2009 in honor of
Prof. Margarita A. Man'ko in connection with her 70th birthday, minor
misprints are corrected in the second versio
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