Future wave climate over the west-European shelf seas

In this paper, we investigate changes in the wave climate of the west-European shelf seas under global warming scenarios. In particular, climate change wind fields corresponding to the present (control) time-slice 1961–2000 and the future (scenario) time-slice 2061–2100 are used to drive a wave generation model to produce equivalent control and scenario wave climate. Yearly and seasonal statistics of the scenario wave climates are compared individually to the corresponding control wave climate to identify relative changes of statistical significance between present and future extreme and prevailing wave heights. Using global, regional and linked global–regional wind forcing over a set of nested computational domains, this paper further demonstrates the sensitivity of the results to the resolution and coverage of the forcing. It suggests that the use of combined forcing from linked global and regional climate models of typical resolution and coverage is a good option for the investigation of relative wave changes in the region of interest of this study. Coarse resolution global forcing alone leads to very similar results over regions that are highly exposed to the Atlantic Ocean. In contrast, fine resolution regional forcing alone is shown to be insufficient for exploring wave climate changes over the western European waters because of its limited coverage. Results obtained with the combined global–regional wind forcing showed some consistency between scenarios. In general, it was shown that mean and extreme wave heights will increase in the future only in winter and only in the southwest of UK and west of France, north of about 44–45° N. Otherwise, wave heights are projected to decrease, especially in summer. Nevertheless, this decrease is dominated by local wind waves whilst swell is found to increase. Only in spring do both swell and local wind waves decrease in average height

In vitro effect of canine hyperimmune sera on TNFa activity

[Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5]. The syndrome is characterized by cardiovascular dysfunction, vascular permeability alterations, pulmonary oedema and tissue hypoxia resulting from microthrombi which may culminate in disseminated intravascular coagulation and catastrophic multiple organ failure [6,7]. Systemic bacterial infection, particularly by Gram-negative enterobacteria, haemorrhagic trauma, gastric dilation/volvulus and pancreatitis are the major underlying causes leading tosepsis [8,9]. Because of haemodynamic instability and associated hypovolemia, fluid replacement therapy is generally applied to restore effective circulating volume. The use of fresh frozen plasma has been recommended in cases of coagulopathies as it has been recognized to assist restoration of haemodynamic stability [1,5,10,11]. There is increasing evidence that the drivers of the haemodynamic instability are inflammatory mediators (particularly TNFa) activated primarily by bacterial endotoxin [3,4,12,13]

Reduction of blocking artifacts in both spatial domain and transformed domain

In this paper, we propose a bi-domain technique to reduce the blocking artifacts commonly incurred in image processing. Some pixels are sampled in the shifted image block and some high frequency components of the corresponding transformed block are discarded. By solving for the remaining unknown pixel values and the transformed coefficients, a less blocky image is obtained. Simulation results using the Discrete Cosine Transform and the Slant Transform show that the proposed algorithm gives a better quantitative result and image quality than that of the existing methods

The Fate of the Language is the Fate of the People: A Cultural Analysis of Language Education Policy in Central Asia

With a shared history under the Soviet Union, the five Central Asian republics of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan have spent the past one hundred years dealing with quickly changing language policy and ethnic relations. Under the policy of the USSR, native languages of Central Asia were repressed, and Russian was introduced as the main language of interethnic communication. After they gained independence in 1991, however, each of the five countries embarked on missions to restore the strength of each of their national languages and de-Russify their political, economic, and educational systems. Throughout the region, one of the main tools of this nation-building and language reform has been primary and secondary school education. Of particular concern in these five contexts—which languages to use as mediums of instruction, which languages to be taught as subjects, and which languages to exclude entirely. This thesis will compare the different goals regarding language policy in each country and the role of multilingualism in their societies, explore the methods each country has taken within their education systems to attempt to alter their modern linguistic setting, identify any significant issues in their plans, and analyze the degree of success that each country has seen in achieving their goal