331 research outputs found

    BEP Performance Analysis of Multi-Node Self Encoded Spread Spectrum - Cooperative Diversity in Rayleigh Fading Channel

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    Self - encoded spread spectrum (SESS) is a novel modulation technique th at acquires its spreading sequence from the random input data stream rather than through the use of the traditional pseudo - noise code generator. It has been incorporated with multi node cooperative diversity systems as a means to combat fading in wireless channels. In this paper we analyze the cooperative SESS for Amplify and Forward CD links ( M SESS - AFCD) and SESS for Decode and forward CD links ( M SESS - DFCD) in Rayleigh fading channels. The BE P expressions are derived in closed form, and the veracity of the analysis is confirmed by numerical calculations that demonstrate excellent agreement with simulation results

    Pregnancy related acute kidney injury: nondialytic management

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    Acute Kidney Injury (AKI) is associated with increased mortality and morbidity unless timely diagnosed & promptly managed. An understanding of the renal physiologic changes that occur during pregnancy is essential for Proper evaluation, diagnosis, and management of Pregnancy Related AKI (PRAKI). In the general population, AKI can occur from prerenal, intrinsic/renal, and post-renal causes. Major causes of pre-renal azotemia include hyperemesis gravidarum and uterine hemorrhage in the setting of placental abruption. Intrinsic etiologies include infections from acute pyelonephritis and septic abortion, bilateral cortical necrosis, and acute tubular necrosis. Particular attention should be paid to specific conditions that lead to AKI during the second and third trimesters, such as preeclampsia, HELLP syndrome, acute fatty liver of pregnancy, and TTP-HUS. An understanding of the various etiologies of AKI in the pregnant patient is key to the appropriate clinical management & prevention of adverse maternal/fetal outcomes. Sometimes PRAKI may require intensive management and even dialysis adding additional economical burden to the patient. We here, with report an interesting case of PRAKI diagnosed & managed in time by simple medical measures thus delivering an effective treatment at a much lesser cost

    Protective effect of Acampe praemorsa (Roxb.) Blatt. & McCann against oxidative stress

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    The current study was carried to make available phytochemical information and evaluation of antioxidant activity of Acampe praemorsa (Roxb.) Blatt. & McCann. The phytochemical analysis was carried out using procedures and quantified phenolic and alkaloid contents. The antioxidant activity was evaluated by in-vitro and in-vivo studies. The In-vitro antioxidant activity was carried on free radicals such as superoxide, hydroxyl DPPH, hydrogen peroxide, evaluation of reducing power. In-vivo study was carried on albino Wistar rats with different doses of extracts. The results provide that, A. praemorsa extracts have diversified phytochemicals in extracts like steroids, alkaloids, phenolics, glycosides, oils, quinones, tannins etc. The hydroalcoholic extract has more phenolic (26.80Ā±0.51) and alkaloid (20.59Ā±0.22) contents. The antioxidant activity results provide information that the extracts possess concentration dependent activity on tested free radicals. The hydroalcoholic extract has more protective nature against superoxide, DPPH, H2O2 free radicals and reducing power but ethyl acetate extract has more potential against hydroxyl free radical than hydroalcoholic extract. The extracts were found to be safe on toxic studies and In-vivo study results and they play significant role in controlling the oxidative enzymes such as catalase, superoxide dismutase, lipid peroxidation (malonaldehyde) in the body. Thus, it was determined that A. praemorsa have potential bioactive compounds and antioxidant activity

    HEREDITORY GINGIVAL FIBROMATOSIS IN A 7-YEAR-OLD GIRL: A CASE REPORT

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    ABSTRACTThis paper presents a case of hereditary gingival fibromatosis, a rarely reported disorder and addresses the complex nature of oral diagnosis,treatment and long-term case management in the hereditary form of recurrent gingival fibromatosis. Case management is discussed in relation toa 7-year-old girl who presented with recurrent, progressive gingival enlargement requiring consecutive periodontal treatment. The initial course oftreatment included 4-quadrant gingivectomy with excisional bevel incisions, followed by microscopic examination of the gingivectomy specimenswhich supported the clinical diagnosis. 1 year later, recurrence of the condition was observed in all quadrants. It is recommended that patients withthis condition be monitored closely after gingivectomy so that the treatment requirements of localized areas can be addressed as needed.Keywords: Heredity, Genome, Phenotype, Chromosome, Autosomal inheritance

    ASSESSMENT OF 10-YEAR RISK OF DEVELOPING A MAJOR CARDIOVASCULAR EVENT IN PATIENTS ATTENDING A HOSPITAL FOR THE TREATMENT OF OTHER DISORDERS

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    Objective: To assess the individualā€™s predicted risk of developing a CVD event in 10 y using risk scores among persons with other disorders/diseases. Methods: This is a cross-sectional observational study conducted for a period of 6 mo among 283 subjects. Total risk was estimated individually by using Framingham Risk Scoring Algorithm and ASCVD risk estimator. Results: According to Framingham Risk score the prevalence of low risk (<10%) identified as 67.84% (192), followed by intermediate risk (10%-19%), 19.08% (54), and high risk (ā‰„20%) 13.07% (37). By using ASCVD Risk estimator, risk has reported in our study population was low risk (<5%) is 48.76% (138), borderline risk (5-7.4%) is 13.07% (37), intermediate risk (7.5-19.9%) is about 25.09% (71), high risk (>20%) is about 13.07% (37). Conclusion: In this study burden of CVD risk was relatively low, which was estimated by both the Framingham scale and ASCVD Risk estimator. Risk scoring of individuals helps us to identify the patients at high risk of CV diseases and also helps in providing management strategies

    An efficient sound and data steganography based secure authentication system

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    The prodigious advancements in contemporary technologies have also brought in the situation of unprecedented cyber-attacks. Further, the pin-based security system is an inadequate mechanism for handling such a scenario. The reason is that hackers use multiple strategies for evading security systems and thereby gaining access to private data. This research proposes to deploy diverse approaches for authenticating and securing a connection amongst two devices/gadgets via sound, thereby disregarding the pinsā€™ manual verification. Further, the results demonstrate that the proposed approaches outperform conventional pin-based authentication orQR authentication approaches. Firstly, a random signal is encrypted, and then it is transformed into a wave file, after which it gets transmitted in a short burst via the deviceā€™s speakers. Subsequently, the other device/gadget captures these audio bursts through its microphone and decrypts the audio signal for getting the essential data for pairing. Besides, this model requires two devices/gadgets with speakers and a microphone, and no extra hardware such as a camera, for reading the QR code is required. The first module is tested with real-time data and generates high scores for the widely accepted accuracy metrics, including precision, Recall, F1 score, entropy, and mutual information (MI). Additionally, this work also proposes a module helps in a secured transmission of sensitive data by encrypting it over images and other files. This steganographic module includes two-stage encryption with two different encryption algorithms to transmit data by embedding inside a file. Several encryption algorithms and their combinations are taken for this system to compare the resultant file size. Both these systems engender high accuracies and provide secure connectivity, leading to a sustainable communication ecosystem.peer-reviewe

    Yoga-Based Cardiac Rehabilitation After Acute Myocardial Infarction: A Randomized Trial

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    Background: Given the shortage of cardiac rehabilitation (CR) programs in India and poor uptake worldwide, there is an urgent need to find alternative models of CR that are inexpensive and may offer choice to subgroups with poor uptake (e.g., women and elderly). Objectives: This study sought to evaluate the effects of yoga-based CR (Yoga-CaRe) on major cardiovascular events and self-rated health in a multicenter randomized controlled trial. Methods: The trial was conducted in 24 medical centers across India. This study recruited 3,959 patients with acute myocardial infarction with a median and minimum follow-up of 22 and 6 months. Patients were individually randomized to receive either a Yoga-CaRe program (n = 1,970) or enhanced standard care involving educational advice (n = 1,989). The co-primary outcomes were: 1) first occurrence of major adverse cardiovascular events (MACE) (composite of all-cause mortality, myocardial infarction, stroke, or emergency cardiovascular hospitalization); and 2) self-rated health on the European Quality of Lifeā€“5 Dimensionsā€“5 Level visual analogue scale at 12 weeks. Results: MACE occurred in 131 (6.7%) patients in the Yoga-CaRe group and 146 (7.4%) patients in the enhanced standard care group (hazard ratio with Yoga-CaRe: 0.90; 95% confidence interval [CI]: 0.71 to 1.15; p = 0.41). Self-rated health was 77 in Yoga-CaRe and 75.7 in the enhanced standard care group (baseline-adjusted mean difference in favor of Yoga-CaRe: 1.5; 95% CI: 0.5 to 2.5; p = 0.002). The Yoga-CaRe group had greater return to pre-infarct activities, but there was no difference in tobacco cessation or medication adherence between the treatment groups (secondary outcomes). Conclusions: Yoga-CaRe improved self-rated health and return to pre-infarct activities after acute myocardial infarction, but the trial lacked statistical power to show a difference in MACE. Yoga-CaRe may be an option when conventional CR is unavailable or unacceptable to individuals. (A study on effectiveness of YOGA based cardiac rehabilitation programme in India and United Kingdom; CTRI/2012/02/002408)

    Evidence-based assessment of antiosteoporotic activity of petroleum-ether extract of Cissus quadrangularis Linn. on ovariectomy-induced osteoporosis

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    The increasing incidence of postmenopausal osteoporosis and its related fractures have become global health issues in the recent days. Postmenopausal osteoporosis is the most frequent metabolic bone disease; it is characterized by a rapid loss of mineralized bone tissue. Hormone replacement therapy has proven efficacious in preventing bone loss but not desirable to many women due to its side-effects. Therefore we are in need to search the natural compounds for a treatment of postmenopausal symptoms in women with no toxic effects. In the present study, we have evaluated the effect of petroleum-ether extract of Cissus quadrangularis Linn. (CQ), a plant used in folk medicine, on an osteoporotic rat model developed by ovariectomy. In this experiment, healthy female Wistar rats were divided into four groups of six animals each. Group 1 was sham operated. All the remaining groups were ovariectomized. Group 2 was fed with an equivolume of saline and served as ovariectomized control (OVX). Groups 3 and 4 were orally treated with raloxifene (5.4 mg/kg) and petroleum-ether extract of CQ (500 mg/kg), respectively, for 3 months. The findings were assessed on the basis of animal weight, morphology of femur, and histochemical localization of alkaline phosphatase (ALP) (an osteoblastic marker) and tartrate-resistant acid phosphatase (TRAP) (an osteoclastic marker) in upper end of femur. The study revealed for the first time that the petroleum-ether extract of CQ reduced bone loss, as evidenced by the weight gain in femur, and also reduced the osteoclastic activity there by facilitating bone formation when compared to the OVX group. The osteoclastic activity was confirmed by TRAP staining, and the bone formation was assessed by ALP staining in the femur sections. The color intensity of TRAP and ALP enzymes from the images were evaluated by image analysis software developed locally. The effect of CQ was found to be effective on both enzymes, and it might be a potential candidate for prevention and treatment of postmenopausal osteoporosis. The biological activity of CQ on bone may be attributed to the phytogenic steroids present in it
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