9,309 research outputs found

    The Residue of a Deep Past: Struggle over cultural transmission in southwest China

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    This thesis examines the cultural past of the nɑχɑ people living in Zheba, a rural mountainous area in southwest China. They perceive and live their cultural past through unreconciled fragments that are deeply embedded in their everyday lives. It is a deep past that continuously gives meanings to local people’s existences, even through times when wellbeing in life is most at stake. I trace the nɑχɑ people’s struggles to reclaim the deep past across time through their multi-layered practices of place making, in the experience of the physical body, the domestic environment, the local landscape and beyond. These practices are crucial means to inhabit a world at the margins of the Chinese nation-state. It is a world in which decades of state sponsored violence followed by market changes in the late twentieth century have caused massive social suffering and cultural dislocation. These struggles thus take place against a decades-long background of huge shifts and ruptures in almost every aspect of everyday life. Whilst reshaping local ways of living, these radical transformations have at the same time generated nuanced ways for local people to live with unprecedented uncertainties and contingencies in their life courses. The struggle to balance the tenstion between change and continuity therefore involves unremitting efforts to transmit the fragmented deep past as imperative dimensions of people’s present and future

    Transition behavior of k-surface from hyperbola to ellipse

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    The transition behavior of the k-surface of a lossy anisotropic indefinite slab is investigated. It is found that, if the material loss is taken into account, the k-surface does not show a sudden change from hyperbola to the ellipse when one principle element of the permittivity tensor changes from negative to positive. In fact, after introducing a small material loss, the shape of the k-surface can be a combination of a hyperbola and an ellipse, and a selective high directional transmission can be obtained in such a slab

    Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts.

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    Pancreatic cancer is a complex disease, in need of new therapeutic approaches. In this study, we explored the effect and mechanism of action of epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, alone and in combination with current chemotherapeutics on pancreatic cancer cell growth, focusing on glycolysis metabolism. Moreover, we investigated whether EGCG's effect is dependent on its ability to induce reactive oxygen species (ROS). EGCG reduced pancreatic cancer cell growth in a concentration-dependent manner and the growth inhibition effect was further enhanced under glucose deprivation conditions. Mechanistically, EGCG induced ROS levels concentration-dependently. EGCG affected glycolysis by suppressing the extracellular acidification rate through the reduction of the activity and levels of the glycolytic enzymes phosphofructokinase and pyruvate kinase. Cotreatment with catalase abrogated EGCG's effect on phosphofructokinase and pyruvate kinase. Furthermore, EGCG sensitized gemcitabine to inhibit pancreatic cancer cell growth in vitro and in vivo. EGCG and gemcitabine, given alone, reduced pancreatic tumor xenograft growth by 40% and 52%, respectively, whereas the EGCG/gemcitabine combination reduced tumor growth by 67%. EGCG enhanced gemcitabine's effect on apoptosis, cell proliferation, cell cycle and further suppressed phosphofructokinase and pyruvate kinase levels. In conclusion, EGCG is a strong combination partner of gemcitabine reducing pancreatic cancer cell growth by suppressing glycolysis

    Symmetry protected fractional Chern insulators and fractional topological insulators

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    In this paper we construct fully symmetric wavefunctions for the spin-polarized fractional Chern insulators (FCI) and time-reversal-invariant fractional topological insulators (FTI) in two dimensions using the parton approach. We show that the lattice symmetry gives rise to many different FCI and FTI phases even with the same filling fraction ν\nu (and the same quantized Hall conductance σxy\sigma_{xy} in FCI case). They have different symmetry-protected topological orders, which are characterized by different projective symmetry groups. We mainly focus on FCI phases which are realized in a partially filled band with Chern number one. The low-energy gauge groups of a generic σxy=1/me2/h\sigma_{xy}=1/m\cdot e^2/h FCI wavefunctions can be either SU(m)SU(m) or the discrete group ZmZ_m, and in the latter case the associated low-energy physics are described by Chern-Simons-Higgs theories. We use our construction to compute the ground state degeneracy. Examples of FCI/FTI wavefunctions on honeycomb lattice and checkerboard lattice are explicitly given. Possible non-Abelian FCI phases which may be realized in a partially filled band with Chern number two are discussed. Generic FTI wavefunctions in the absence of spin conservation are also presented whose low-energy gauge groups can be either SU(m)×SU(m)SU(m)\times SU(m) or Zm×ZmZ_m\times Z_m. The constructed wavefunctions also set up the framework for future variational Monte Carlo simulations.Comment: 24 pages, 13 figures, published versio

    The Genuine Savings Criterion and the Value of Population

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    Arrow, Dasgupta and Maler demonstrate thatin any dynamic model of the economy with changing population, population should properly be one of the state variables of the system. It enters both in the maxim and, at least under total utilitarianism, and into the production function in one way or another. If population growth is exponential and there are constant returns to scale, then a simple transformation to per capita variables can be used to eliminate one state variable. However, this simple transformation cannot be made if growth is not exponential, as it obviously is not and cannot be. If the growth of population is exogenous, then introducing it into the system does not affect the optimal policy. However, if one asks whether the system is sustainable, in the sense of at least maintaining total welfare (integral of discounted utilities), then the criterion is that the value of the rates of change of the state variables is non-negative, so that the shadow price of population becomes relevant. In this paper, we derive explicit formulas in a simple model, showing that the rate of growth of per capita capital is not the correct formula but must have other terms added to it. We also study the question under an alternative criterion of long-run average utilitarianism.

    Spontaneous spin ordering of Dirac spin liquid in a magnetic field

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    The Dirac spin liquid was proposed to be the ground state of the spin-1/2 Kagome antiferromagnets. In a magnetic field BB, we show that the state with Fermi pocket is unstable to the Landau level (LL) state. The LL state breaks the spin rotation around the axis of the magnetic field. We find that the LL state has an in-plane 120^{\circ} q=0q=0 magnetization MM which scales with the external field MBαM\sim B^{\alpha}, where α\alpha is an intrinsic calculable universal number of the Dirac spin liquid. We discuss the related experimental implications which can be used to detect the possible Dirac spin liquid phase in Herbertsmithite ZnCu3_3(OH)6_6Cl2_2.Comment: rewritten for clarit

    Topological surface states in three-dimensional magnetic insulators

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    An electron moving in a magnetically ordered background feels an effective magnetic field that can be both stronger and more rapidly varying than typical externally applied fields. One consequence is that insulating magnetic materials in three dimensions can have topologically nontrivial properties of the effective band structure. For the simplest case of two bands, these "Hopf insulators" are characterized by a topological invariant as in quantum Hall states and Z_2 topological insulators, but instead of a Chern number or parity, the underlying invariant is the Hopf invariant that classifies maps from the 3-sphere to the 2-sphere. This paper gives an efficient algorithm to compute whether a given magnetic band structure has nontrivial Hopf invariant, a double-exchange-like tight-binding model that realizes the nontrivial case, and a numerical study of the surface states of this model.Comment: 4 pages, 2 figures; published versio
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