56 research outputs found

    Development of a small scale semi-intensive prawn hatchery and its role in the development of brakishwater prawn farming in Orissa

    Get PDF
    To develop a continuous seed production technology, particularly of Penaeus monodon, which has maximum demand in brackishwater culture system, a small scale hatchery was designed at Purl Centre In l984-'85 under a semi-intensive system and operated using recirculated water through a biological filtration system. The details of hatchery lay out, tanks, filters, water and air systems, maintenance of breeders, and feeds are given. The system is semi-intensive in the sense that developed feeds were used and salinity and pH were controlled to suit the hatchery needs. The problems encountered in the hatchery such as spawner availability, transportation stress, impact of environmental factors, water quality etc are discussed. The system and its cost of management are brought out with a view towards its suitability as a small scale operation under Indian conditions

    Association of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)

    Get PDF
    BACKGROUND: Based on the site of breakpoint in t(9;22) (q34;q11), bcr-abl fusion in leukemia patients is associated with different types of transcript proteins. In this study we have seen the association of HLA genes with different types of bcr-abl transcripts. The association could predict the bcr-abl peptide presentation by particular HLA molecules. METHODS: The study included a total of 189 patients of mixed ethnicity with chronic myelogenous leukemia and acute lymphocytic leukemia who were being considered for bone marrow transplantation. Typing of bcr-abl transcripts was done by reverse transcriptase PCR method. HLA typing was performed by molecular methods. The bcr-abl and HLA association was studied by calculating the relative risks and chi-square test. RESULTS: Significant negative associations (p < 0.05) were observed with HLA-A*02 (b2a2, e1a2), -A*68 (b2a2, b3a2, e1a2), -B*14 (b2a2, b3a2, e1a2), -B*15 (b2a2, b3a2), -B*40 (b2a2), -DQB1*0303 (b2a2, b3a2), -DQB1*0603 (b2a2), -DRB1*0401 (e1a2), -DRB1*0701 (b3a2), and -DRB1*1101 (b2a2). CONCLUSIONS: The negative associations of a particular bcr-abl transcript with specific HLA alleles suggests that these alleles play a critical role in presenting peptides derived from the chimeric proteins and eliciting a successful T-cell cytotoxic response. Knowledge of differential associations between HLA phenotypes and bcr-abl fusion transcript types would help in developing better strategies for immunization with the bcr-abl peptides against t(9;22) (q34;q11)-positive leukemia

    Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Nutritional vitamin D deficiency is an emerging risk factor for acute myocardial infarction (AMI) and heart failure. The association of 25-hydroxyvitamin D levels with N-terminal pro B-type natriuretic peptide (NT-proBNP), a robust prognostic marker for post-AMI mortality and heart failure, is unknown and could illuminate a potential pathway for adverse outcomes among post-AMI patients with 25-hydroxyvitamin D deficiency.</p> <p>Methods</p> <p>In a cross-sectional analysis, we studied 238 AMI patients from 21 U.S. centers to test the association of nutritional vitamin D (25-hydroxyvitamin D [25(OH)D]) deficiency with NT-proBNP levels. Levels of 25(OH)D levels were categorized as normal (≥30 ng/mL), insufficient (>20 - <30 ng/mL), deficient (>10 - ≤20 ng/mL), or severely deficient (≤10 ng/mL).</p> <p>Results</p> <p>Low 25(OH)D levels were found in 95.7% of AMI patients. No significant trends for higher mean baseline log NT-proBNP levels in severely deficient (6.9 ± 1.3 pg/mL), deficient (6.9 ± 1.2 pg/mL), and insufficient (6.9 ± 0.9 pg/ml) groups were observed as compared with patients having normal (6.1 ± 1.7 pg/mL) levels, <it>P </it>= 0.17. Findings were similar in the subset of patients who had follow-up NT-proBNP levels drawn at one month. In multivariate regression modeling, after adjusting for multiple covariates, 25(OH)D was not associated with NT-proBNP.</p> <p>Conclusions</p> <p>Potential associations between nutritional vitamin D deficiency and prognosis in the setting of AMI are unlikely to be mediated through NT-proBNP pathways. Future studies should examine other mechanisms, such as inflammation and vascular calcification, by which 25(OH)D deficiency could mediate adverse outcomes post-AMI.</p

    Not Available

    No full text
    Not AvailableThe distribution of different species of prawns in the various estuarine systema of Orissa ooast are discussed in relation to their habitat preference and the ecological conditions. In the recent years, with the ahanging ecological conditions, grater reoruitment and establishment of Penaeus semisulcatus and Penaeus joponicus juvenile population wae obssrved in high salinity zone of various estuaries and lagoons. The gradual encroachment of these species in the erstwhile Penaeus monodoo nursery grourid, its probable causes and effects on the recruitment and fishery of P. monodon are discussed The probable migratory pattern of these species is disoussed in relaticn to the distribution of their adult populationNot Availabl

    Not Available

    No full text
    Not AvailableTo develop a continuous seed production technology, particularly of Penaeus monodon, which has maximum demand in brackishwater culture system, a small scale hatchery was designed at Purl Centre In l984-'85 under a semi-intensive system and operated using recirculated water through a biological filtration system. The details of hatchery lay out, tanks, filters, water and air systems, maintenance of breeders, and feeds are given. The system is semi-intensive in the sense that developed feeds were used and salinity and pH were controlled to suit the hatchery needs. The problems encountered in the hatchery such as spawner availability, transportation stress, impact of environmental factors, water quality etc are discussed. The system and its cost of management are brought out with a view towards its suitability as a small scale operation under Indian conditions.Not Availabl
    corecore