COVID-19: Policy Interventions and Socio-economic Impact in Andhra Pradesh, India

The COVID-19 pandemic has claimed several lives and has already adversely affected the livelihoods of millions of vulnerable households. This policy brief surveys the current status of the disease, its spread and its likely socio-economic effects in the context of Andhra Pradesh, India. Given the global scope of the shock, the policy brief emphasizes the need for innovative and bold policy measures, particularly from the states’ perspective

Alternate paths to economic development:a comparative analysis of Brazil and India in the era of neoliberalism

ABSTRACT This paper compares and contrasts Brazilian and Indian strategies of development during the era of neo-liberalism from a long period perspective. The Brazilian economy has attempted to combine the goals of redistribution and social equity with the goals of growth and productivity. India on the other hand has pursued a growth maximizing approach to development, while paying little or no attention to the larger goals of human well-being. The article seeks to understand the dynamics of economic change in the two economies and attempts to draw out the institutional and political factors that have influenced these approaches

COVID-19: Policy Interventions and Socio-economic Impact in Andhra Pradesh, India

The COVID-19 pandemic has claimed several lives and has already adversely affected the livelihoods of millions of vulnerable households. This policy brief surveys the current status of the disease, its spread and its likely socio-economic effects in the context of Andhra Pradesh, India. Given the global scope of the shock, the policy brief emphasizes the need for innovative and bold policy measures, particularly from the states’ perspective

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field