Generating functional analysis of complex formation and dissociation in large protein interaction networks

We analyze large systems of interacting proteins, using techniques from the non-equilibrium statistical mechanics of disordered many-particle systems. Apart from protein production and removal, the most relevant microscopic processes in the proteome are complex formation and dissociation, and the microscopic degrees of freedom are the evolving concentrations of unbound proteins (in multiple post-translational states) and of protein complexes. Here we only include dimer-complexes, for mathematical simplicity, and we draw the network that describes which proteins are reaction partners from an ensemble of random graphs with an arbitrary degree distribution. We show how generating functional analysis methods can be used successfully to derive closed equations for dynamical order parameters, representing an exact macroscopic description of the complex formation and dissociation dynamics in the infinite system limit. We end this paper with a discussion of the possible routes towards solving the nontrivial order parameter equations, either exactly (in specific limits) or approximately.Comment: 14 pages, to be published in Proc of IW-SMI-2009 in Kyoto (Journal of Phys Conference Series

1D generalized statistics gas: A gauge theory approach

A field theory with generalized statistics in one space dimension is introduced. The statistics enters the scene through the coupling of the matter fields to a statistical gauge field, as it happens in the Chern-Simons theory in two dimensions. We study the particle-hole excitations and show that the long wave length physics of this model describes a gas obeying the Haldane generalized exclusion statistics. The statistical interaction is found to provide a way to describe the low-T critical properties of one-dimensional non-Fermi liquids.Comment: 8 pages, revte

On the physical interpretation of effective actions using Schwinger's formula

We show explicitly that Schwinger's formula for one-loop effective actions corresponds to the summation of energies associated with the zero-point oscillations of the fields. We begin with a formal proof, and after that we confirm it using a regularization prescription.Comment: 5 p., REVTEX, IF-UFRJ-9

Prediction of metabolizable energy values in poultry offal meal for broiler chickens.

Projeto/Plano de Ação: 16.00.300.04-00

Electromagnetic Response and Approximate SO(5) Symmetry in High-Tc Superconductors

It has been proposed that the effective Hamiltonian describing high T_c superconductivity in cuprate materials has an approximate SO(5) symmetry relating the superconducting (SC) and antiferromagnetic (AF) phases of these systems. We show that robust consequences of this proposal are potentially large optical conductivities and Raman scattering rates in the AF phase, due to the electromagnetic response of the doubly-charged pseudo Goldstone bosons which must exist there. This provides strong constraints on the properties of the bosons, such as their mass gap and velocity.Comment: 4 pages, 3 figure