Pseudoscalar pole terms contributions to hadronic light-by-light corrections to the muonium hyperfine splitting

The contribution of pseudoscalar pole diagrams to the hadronic light-by-light corrections of order alpha^3 E_F to the ground state hyperfine splitting in hydrogenic atom is calculated in the pseudoscalar pole terms approximation. The vector dominance model for the form factor of the transition of a pseudoscalar meson into two photons is used. With the account of new experimental data on the cross sections sigma (e^+e^-\to \rho, \omega \to \pi^0(\eta)\gamma) in the SND and CMD-2 experiments some other hadronic corrections to the muonium hyperfine splitting are calculated.Comment: 7 pages, REVTEX, 5 figure

Study of an Alternate Mechanism for the Origin of Fermion Generations

In usual extended technicolor (ETC) theories based on the group ${\rm{SU}(N_{ETC}})_{ETC}$, the quarks of charge 2/3 and -1/3 and the charged leptons of all generations arise from ETC fermion multiplets transforming according to the fundamental representation. Here we investigate a different idea for the origin of SM fermion generations, in which quarks and charged leptons of different generations arise from ETC fermions transforming according to different representations of ${\rm{SU}(N_{ETC}})_{ETC}$. Although this mechanism would have the potential, {\it a priori}, to allow a reduction in the value of $N_{ETC}$ relative to conventional ETC models, we show that, at least in simple models, it is excluded by the fact that the technicolor sector is not asymptotically free or by the appearance of fermions with exotic quantum numbers which are not observed.Comment: 6 pages, late

Mesoscopic modelling of financial markets

We derive a mesoscopic description of the behavior of a simple financial market where the agents can create their own portfolio between two investment alternatives: a stock and a bond. The model is derived starting from the Levy-Levy-Solomon microscopic model (Econ. Lett., 45, (1994), 103--111) using the methods of kinetic theory and consists of a linear Boltzmann equation for the wealth distribution of the agents coupled with an equation for the price of the stock. From this model, under a suitable scaling, we derive a Fokker-Planck equation and show that the equation admits a self-similar lognormal behavior. Several numerical examples are also reported to validate our analysis

Optical spectroscopy of the radio pulsar PSR B0656+14

We have obtained the spectrum of a middle-aged PSR B0656+14 in the 4300-9000 AA range with the ESO/VLT/FORS2. Preliminary results show that at 4600-7000 AA the spectrum is almost featureless and flat with a spectral index $\alpha_nu ~ -0.2 that undergoes a change to a positive value at longer wavelengths. Combining with available multiwavelength data suggests two wide, red and blue, flux depressions whose frequency ratio is about 2 and which could be the 1st and 2nd harmonics of electron/positron cyclotron absorption formed at magnetic fields ~10^8G in upper magnetosphere of the pulsar.Comment: 4 pages, 4 figures, To appear in Astrophysics and Space Science, Proceedings of "Isolated Neutron Stars: from the Interior to the Surface", eds. D. Page, R. Turolla and S. Zan

Radiatively Induced Neutrino Masses and Large Higgs-Neutrino Couplings in the Standard Model with Majorana Fields

The Higgs sector of the Standard Model with one right-handed neutrino per family is systematically analyzed. In a model with intergenerational independent mixings between families, we can account for very light neutrinos acquiring Majorana masses radiatively at the first electroweak loop level. We also find that in such a scenario the Higgs coupling to the light-heavy neutrinos and to the heavy-heavy ones may be remarkably enhanced with significant implications for the production of these heavy neutrinos at high energy colliders.Comment: Making the text of an old paper electronically availabl

Designed antitumor peptide for targeted siRNA delivery into cancer spheroids

Antimicrobial/anticancer peptides (AMPs/ACPs) have shown promising results as new therapeutic agents in cancer therapy. Among them, the designed amphiphilic α-helical peptide G(IIKK)3I-NH2 (G3) displayed great affinity and specificity in targeting cancer cells. Here, we report new insights on how G3 penetrates cancer cells. G3 showed high specificity to HCT-116 colon cancer cells compared to the HDFs (human neonatal primary dermal fibroblasts) control. With high concentrations of peptide, a clear cancer cell membrane disruption was observed through SEM. Gene knockdown of the endocytic pathways demonstrated that an energy-dependent endocytic pathway is required for the uptake of the peptide. In addition, G3 can protect and selectively deliver siRNAs into cancer cells and successfully modulated their gene expression. Gene delivery was also tested in 3D cancer spheroids and showed deep penetration delivery into the cancer spheroids. Finally, the in vivo toxicity of G3 was evaluated on zebrafish embryos, showing an increasing toxicity effect with concentration. However, the toxicity of the peptide was attenuated when complexed with siRNA. In addition, negligible toxicity was observed at the concentration range for efficient gene delivery. The current results demonstrate that G3 is promising as an excellent agent for cancer therapy

Long Range Magnetic Order and the Darwin Lagrangian

We simulate a finite system of $N$ confined electrons with inclusion of the Darwin magnetic interaction in two- and three-dimensions. The lowest energy states are located using the steepest descent quenching adapted for velocity dependent potentials. Below a critical density the ground state is a static Wigner lattice. For supercritical density the ground state has a non-zero kinetic energy. The critical density decreases with $N$ for exponential confinement but not for harmonic confinement. The lowest energy state also depends on the confinement and dimension: an antiferromagnetic cluster forms for harmonic confinement in two dimensions.Comment: 5 figure

Hydrodynamics, particle relabelling and relativity

Using the wave equation as an example, it is shown how to extend the hydrodynamic Lagrangian-picture method of constructing field evolution using a continuum of trajectories to second-order theories. The wave equation is represented through Eulerian-picture models that are distinguished by their Lorentz transformation properties. Introducing the idea of the relativity of the particle label, it is demonstrated how the corresponding trajectory models are compatible with the relativity principle. It is also shown how the Eulerian variational formulation may be obtained by canonical transformation from the Lagrangian picture, and how symmetries in the Lagrangian picture may be used to generate Eulerian conserved charges.Comment: 21 page

Lepton flavor violation decays τ−→μ−P1P2\tau^-\to \mu^- P_1 P_2 in the topcolor-assisted technicolor model and the littlest Higgs model with TT parity

The new particles predicted by the topcolor-assisted technicolor ($TC2$) model and the littlest Higgs model with T-parity (called $LHT$ model) can induce the lepton flavor violation ($LFV$) couplings at tree level or one loop level, which might generate large contributions to some $LFV$ processes. Taking into account the constraints of the experimental data on the relevant free parameters, we calculate the branching ratios of the $LFV$ decay processes $\tau^-\to\mu^- P_1 P_2$ with $P_1 P_2$ = $\pi^+\pi^-$, $K^+K^-$ and $K^0\bar{K^0}$ in the context of these two kinds of new physics models. We find that the $TC2$ model and the $LHT$ model can indeed produce significant contributions to some of these $LFV$ decay processes.Comment: 24 pages, 7 figure