74 research outputs found
The measurement of commitment to work
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43493/1/11111_2004_Article_BF00972537.pd
Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19
Anti-SARS-CoV-2 monoclonal antibodies are mainstay COVID-19 therapeutics. Safety, antiviral, and clinical efficacy of bamlanivimab were evaluated in the randomized controlled trial ACTIV-2/A5401. Non-hospitalized adults were randomized 1:1 within 10 days of COVID-19 symptoms to bamlanivimab or blinded-placebo in two dose-cohorts (7000 mg, n = 94; 700 mg, n = 223). No differences in bamlanivimab vs placebo were observed in the primary outcomes: proportion with undetectable nasopharyngeal SARS-CoV-2 RNA at days 3, 7, 14, 21, and 28 (risk ratio = 0.82-1.05 for 7000 mg [p(overall) = 0.88] and 0.81-1.21 for 700 mg [p(overall) = 0.49]), time to symptom improvement (median 21 vs 18.5 days [p = 0.97], 7000 mg; 24 vs 20.5 days [p = 0.08], 700 mg), or grade 3+ adverse events. However, bamlanivimab was associated with lower day 3 nasopharyngeal viral levels and faster reductions in inflammatory markers and viral decay by modeling. This study provides evidence of faster reductions in nasopharyngeal SARS-CoV-2 RNA levels but not shorter symptom durations in non-hospitalized adults with early variants of SARS-CoV-2
Paleobiology of titanosaurs: reproduction, development, histology, pneumaticity, locomotion and neuroanatomy from the South American fossil record
Fil: GarcĂa, Rodolfo A.. Instituto de InvestigaciĂłn en PaleobiologĂa y GeologĂa. Museo Provincial Carlos Ameghino. Cipolletti; ArgentinaFil: Salgado, Leonardo. Instituto de InvestigaciĂłn en PaleobiologĂa y GeologĂa. General Roca. RĂo Negro; ArgentinaFil: Fernández, Mariela. Inibioma-Centro Regional Universitario Bariloche. Bariloche. RĂo Negro; ArgentinaFil: Cerda, Ignacio A.. Instituto de InvestigaciĂłn en PaleobiologĂa y GeologĂa. Museo Provincial Carlos Ameghino. Cipolletti; ArgentinaFil: Carabajal, Ariana Paulina. Museo Carmen Funes. Plaza Huincul. NeuquĂ©n; ArgentinaFil: Otero, Alejandro. Museo de La Plata. Universidad Nacional de La Plata; ArgentinaFil: Coria, Rodolfo A.. Instituto de PaleobiologĂa y GeologĂa. Universidad Nacional de RĂo Negro. NeuquĂ©n; ArgentinaFil: Fiorelli, Lucas E.. Centro Regional de Investigaciones CientĂficas y Transferencia TecnolĂłgica. Anillaco. La Rioja; Argentin
Proteolytic activity of excretory/secretory products of Cochliomyia hominivorax larvae (Diptera: Calliphoridae)
Chapter 8 Setting performance standards for National Board assessments: A reprise on research and development
Networking as a Strategy for Technology Transfer and Commercialization from R&D Laboratories
The microelectronics revolution An assessment of its significance for education and teacher education
Interpreting ambiguous bedforms to distinguish subaerial base surge from subaqueous density current deposits
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