3. The circular restricted three-body problem

<em>The article describes the therapy for atopic dermatitis with topical glucocorticosteroids. Parameters of the «ideal» topical cortico steroid are provided: strong anti-inflammatory effect, low systemic bioavailability, quick action onset, minimal side effects, multiplicity of pharmaceutical forms. It describes results of a number of clinical trials for efficacy and safety of using mometasone furoate in children, a pharmaceutical product close enough to the «ideal» characteristics of a topical corticosteroid.</em><br /><strong><em>Key words: atopic dermatitis, topical glucocorticosteroids, mometasone furoate, children, safety.</em></strong

ALLERGY AND ANTIHISTAMINIC MEDICATIONS

The article reviews the urgent issue of the allergology, which is the application of the antihistaminic medications. The author has demonstrated the advantages of the 2nd generation medications, which have a selective impact on the H1 receptors and do not cause any sedative or anticholinergic effects. She also showed high efficiency of cetirizine, a representative of the given group, for the treatment of the all year round rhinitis and other allergies.Key words: allergies, pathogenesis, treatment, Н1 receptor blockers, children

ALLERGY AND ANTIHISTAMINIC MEDICATIONS

The article reviews the urgent issue of the allergology, which is the application of the antihistaminic medications. The author has demonstrated the advantages of the 2nd generation medications, which have a selective impact on the H1 receptors and do not cause any sedative or anticholinergic effects. She also showed high efficiency of cetirizine, a representative of the given group, for the treatment of the all year round rhinitis and other allergies.Key words: allergies, pathogenesis, treatment, Н1 receptor blockers, children

АЛЛЕРГИЯ И АНТИГИСТАМИННЫЕ ПРЕПАРАТЫ

The article reviews the urgent issue of the allergology, which is the application of the antihistaminic medications. The author has demonstrated the advantages of the 2nd generation medications, which have a selective impact on the H1 receptors and do not cause any sedative or anticholinergic effects. She also showed high efficiency of cetirizine, a representative of the given group, for the treatment of the all year round rhinitis and other allergies.Key words: allergies, pathogenesis, treatment, Н1 receptor blockers, children.В статье рассмотрена актуальная проблема аллергологии – применение антигистаминных препаратов. Автором представлены преимущества лекарственных средств второго и третьего поколения, которые не оказывают седативного и холинолитического эффектов и обладают избирательностью действия на Н1-рецепторы. Продемонстирована высокая эффективность представителя данной группы цетиризина для лечения круглогодичного ринита и других аллергических болезней. Ключевые слова: аллергические болезни, патогенез, лечение, блокаторы Н1-рецепторов, дети.(Педиатрическая фармакология. – 2008;5(3):82-84

MODERN TECHNOLOGIES OF VITAMIN AND MINERAL COMPLEXES PRODUCTION

The article highlights the information on the technology of the vitamin and mineral complexes production, actions to ensure not only high quality production but also safety for the staff and environmental protection.Key words: vitamin and mineral complexes, production technologies

MODERN TECHNOLOGIES OF VITAMIN AND MINERAL COMPLEXES PRODUCTION

The article highlights the information on the technology of the vitamin and mineral complexes production, actions to ensure not only high quality production but also safety for the staff and environmental protection.Key words: vitamin and mineral complexes, production technologies

MULTIVITAMIN EXPERIENCE IN SCHOOLCHILDREN

The article highlights the findings, pertaining to the efficiency and safety of multivitamin Pikovit forte application among children. The researchers came to conclusion that this balanced multivitamin complex is a modern high quality and low allergy medication with a pleasant flavour. It may be applied among children aged over 7 for the intense vitamin based therapy.Key words: multivitamins, children

OMALIZUMAB-BASED TREATMENT OF TEENAGERS, SUFFERING FROM SEVERE ATOPIC BRONCHIAL ASTHMA

Omalizumab, a medicine of the recombinant humanized mono clonal antibodies to Ige, is applied in russia among teenagers throughout a year. it is prescribed to patients with severe persistent incontrolled by iks atopic bronchial asthma (BA). The article generalizes the experience of omalizumab application among teenagers and highlights the first findings in respect of its efficiency and safety. 6 month long omalizumab based treatment contributes to the reduction in the recurrence of the clinically significant BA exacerbations by 65% and the frequency of because hospitalizations by 78%. Against the background of the ongoing treatment, the indices of the bronchial passability get better; the need in the bronchial spasmolytics falls down; BA control improves. Most children have a chance to sizably reduce the dose of the inhalant glucocorticosteroids against the omalizumab based treatment. The authors pointed out to the reduced symptoms of the allergic rhinitis, grass pollen allergy, food allergy among teenagers, who have been receiving the ant Ige therapy for a long time. They also noted the satisfactory profile of omalizumab safety.Key words: omalizumab, ant Ige antibodies, bronchial asthma, treatment, children, teenagers, bronchial asthma control

OMALIZUMAB-BASED TREATMENT OF TEENAGERS, SUFFERING FROM SEVERE ATOPIC BRONCHIAL ASTHMA

Omalizumab, a medicine of the recombinant humanized mono clonal antibodies to Ige, is applied in russia among teenagers throughout a year. it is prescribed to patients with severe persistent incontrolled by iks atopic bronchial asthma (BA). The article generalizes the experience of omalizumab application among teenagers and highlights the first findings in respect of its efficiency and safety. 6 month long omalizumab based treatment contributes to the reduction in the recurrence of the clinically significant BA exacerbations by 65% and the frequency of because hospitalizations by 78%. Against the background of the ongoing treatment, the indices of the bronchial passability get better; the need in the bronchial spasmolytics falls down; BA control improves. Most children have a chance to sizably reduce the dose of the inhalant glucocorticosteroids against the omalizumab based treatment. The authors pointed out to the reduced symptoms of the allergic rhinitis, grass pollen allergy, food allergy among teenagers, who have been receiving the ant Ige therapy for a long time. They also noted the satisfactory profile of omalizumab safety.Key words: omalizumab, ant Ige antibodies, bronchial asthma, treatment, children, teenagers, bronchial asthma control