1,239 research outputs found
Knowledge management and human trafficking: using conceptual knowledge representation, text analytics and open-source data to combat organized crime
Globalization, the ubiquity of mobile communications and the rise of the web have all expanded the environment in which organized criminal entities are conducting their illicit activities, and as a result the environment that law enforcement agencies have to police. This paper triangulates the capability of open-source data analytics, ontological knowledge representation and the wider notion of knowledge management (KM) in order to provide an effective, interdisciplinary means to combat such threats, thus providing law enforcement agencies (LEA’s) with a foundation of competitive advantage over human trafficking and other organized crime
Delivered relative dose intensity in adolescent and young adult germ cell tumours in England: Assessment of data quality and consistency from clinical trials compared to national cancer registration data
Adolescent and young adults (AYA) with germ cell tumours (GCT) have poorer survival rates than children and many older adults with the same cancers. There are several likely contributing factors to this, including the treatment received. The prognostic benefit of intended dose intensity is well documented in GCT from trials comparing regimens. However, evidence specific to AYA is limited by poor recruitment of AYA to trials and dose delivery outside trials not being well examined. We examined the utility of cancer registration data and a clinical trials dataset to investigate the delivery of relative dose intensity (RDI) in routine National Health Service practice in England, compared to within international clinical trials. Linked data from the Cancer Outcomes and Services Dataset (COSD) and the Systemic Anti-Cancer Therapy (SACT) dataset, and data from four international clinical trials were analysed. Survival over time was described using Kaplan-Meier estimation; overall, by age category, International Germ-Cell Cancer Collaborative Group (IGCCCG) classification, stage, tumour subtype, primary site, ethnicity and deprivation. Cox regression models were used to determine the fully adjusted effect of RDI on mortality risk. The quality of both datasets was critically evaluated and clinically enhanced. RDI was found to be well maintained in all datasets with higher RDIs associated with improved survival outcomes. Real-world data demonstrated several strengths, including population coverage and inclusion of sociodemographic variables and comorbidity. It is limited in GCT however, by the poor completion of data items enabling risk classification of patients and a higher proportion of missing data
Destabilization of dark states and optical spectroscopy in Zeeman-degenerate atomic systems
We present a general discussion of the techniques of destabilizing dark
states in laser-driven atoms with either a magnetic field or modulated laser
polarization. We show that the photon scattering rate is maximized at a
particular evolution rate of the dark state. We also find that the atomic
resonance curve is significantly broadened when the evolution rate is far from
this optimum value. These results are illustrated with detailed examples of
destabilizing dark states in some commonly-trapped ions and supported by
insights derived from numerical calculations and simple theoretical models.Comment: 14 pages, 10 figure
Cash Transfers, Young Women’s Economic Well-Being, and HIV Risk: Evidence from HPTN 068
Despite the large interest in economic interventions to reduce HIV risk, little research has been done to show whether there are economic gains of these interventions for younger women and what intermediary role economic resources play in changing participants’ sexual behavior. This paper contributes to this gap by examining the impacts of a conditional cash transfer (CCT) for young women in South Africa on young women’s economic resources and the extent to which they play a role in young women’s health and behavior. We used data from HIV Prevention Trials Network 068 study, which provided transfers to young women (in addition to their parents) conditional on the young woman attending at least 80% of school days in the previous month. We found that the CCT increased young women’s economic wellbeing in terms of having savings, spending money, being unindebted, and food secure. We also investigated heterogeneous effects of the program by household economic status at baseline because the program was not specifically poverty targeted and found that the results were driven by young women from the poorest families. From these results, we examined heterogeneity by baseline poverty for other outcomes related to HIV risk including sexual behavior and psychosocial well-being. We found psychosocial well-being benefits in young women from the poorest families and that economic wellbeing gains explained much these impacts
Nucleon Charge and Magnetization Densities from Sachs Form Factors
Relativistic prescriptions relating Sachs form factors to nucleon charge and
magnetization densities are used to fit recent data for both the proton and the
neutron. The analysis uses expansions in complete radial bases to minimize
model dependence and to estimate the uncertainties in radial densities due to
limitation of the range of momentum transfer. We find that the charge
distribution for the proton is significantly broad than its magnetization
density and that the magnetization density is slightly broader for the neutron
than the proton. The neutron charge form factor is consistent with the Galster
parametrization over the available range of Q^2, but relativistic inversion
produces a softer radial density. Discrete ambiguities in the inversion method
are analyzed in detail. The method of Mitra and Kumari ensures compatibility
with pQCD and is most useful for extrapolating form factors to large Q^2.Comment: To appear in Phys. Rev. C. Two new figures and accompanying text have
been added and several discussions have been clarified with no significant
changes to the conclusions. Now contains 47 pages including 21 figures and 2
table
Linear and Second-order Optical Response of the III-V Mono-layer Superlattices
We report the first fully self-consistent calculations of the nonlinear
optical properties of superlattices. The materials investigated are mono-layer
superlattices with GaP grown on the the top of InP, AlP and GaAs (110)
substrates. We use the full-potential linearized augmented plane wave method
within the generalized gradient approximation to obtain the frequency dependent
dielectric tensor and the second-harmonic-generation susceptibility. The effect
of lattice relaxations on the linear optical properties are studied. Our
calculations show that the major anisotropy in the optical properties is the
result of strain in GaP. This anisotropy is maximum for the superlattice with
maximum lattice mismatch between the constituent materials. In order to
differentiate the superlattice features from the bulk-like transitions an
improvement over the existing effective medium model is proposed. The
superlattice features are found to be more pronounced for the second-order than
the linear optical response indicating the need for full supercell calculations
in determining the correct second-order response.Comment: 9 pages, 4 figures, submitted to Phy. Rev.
CPT, T, and Lorentz Violation in Neutral-Meson Oscillations
Tests of CPT and Lorentz symmetry using neutral-meson oscillations are
studied within a formalism that allows for indirect CPT and T violation of
arbitrary size and is independent of phase conventions. The analysis is
particularly appropriate for studies of CPT and T violation in oscillations of
the heavy neutral mesons D, B_d, and B_s. The general Lorentz- and CPT-breaking
standard-model extension is used to derive an expression for the parameter for
CPT violation. It varies in a prescribed way with the magnitude and orientation
of the meson momentum and consequently also with sidereal time. Decay
probabilities are presented for both uncorrelated and correlated mesons, and
some implications for experiments are discussed.Comment: 11 pages, references added, accepted in Physical Review
Precision Measurement of the Proton and Deuteron Spin Structure Functions g2 and Asymmetries A2
We have measured the spin structure functions g2p and g2d and the virtual
photon asymmetries A2p and A2d over the kinematic range 0.02 < x < 0.8 and 0.7
< Q^2 < 20 GeV^2 by scattering 29.1 and 32.3 GeV longitudinally polarized
electrons from transversely polarized NH3 and 6LiD targets. Our measured g2
approximately follows the twist-2 Wandzura-Wilczek calculation. The twist-3
reduced matrix elements d2p and d2n are less than two standard deviations from
zero. The data are inconsistent with the Burkhardt-Cottingham sum rule if there
is no pathological behavior as x->0. The Efremov-Leader-Teryaev integral is
consistent with zero within our measured kinematic range. The absolute value of
A2 is significantly smaller than the sqrt[R(1+A1)/2] limit.Comment: 12 pages, 4 figures, 2 table
Measurement of the Proton and Deuteron Spin Structure Functions g2 and Asymmetry A2
We have measured the spin structure functions g2p and g2d and the virtual
photon asymmetries A2p and A2d over the kinematic range 0.02 < x < 0.8 and 1.0
< Q^2 < 30(GeV/c)^2 by scattering 38.8 GeV longitudinally polarized electrons
from transversely polarized NH3 and 6LiD targets.The absolute value of A2 is
significantly smaller than the sqrt{R} positivity limit over the measured
range, while g2 is consistent with the twist-2 Wandzura-Wilczek calculation. We
obtain results for the twist-3 reduced matrix elements d2p, d2d and d2n. The
Burkhardt-Cottingham sum rule integral - int(g2(x)dx) is reported for the range
0.02 < x < 0.8.Comment: 12 pages, 4 figures, 1 tabl
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