92 research outputs found

    Spatial segregation measures: a methodological review

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    Quantitative indices of segregation are powerful tools for summarising the spatial relationships between population groups and thereby providing the basis for analysis and public policy intervention. While the broad concept of segregation may be intuitive, measurement is challenging because of the complexity of varied dimensions and spatial arrangements. Many traditional measures can be criticised for over-simplification or over-reduction, not least in their treatment of geographical space. Over the last several decades, however, a series of measures has been developed to explicitly incorporate the spatial arrangement of population groups as well as their interactions. This paper reviews the development of spatial segregation measures, particularly focusing on the mathematical formulation of spatial arrangement/relations. In addition, several related issues are discussed, including representation of spatial interaction, spatial scale and statistical inferences. Also, this paper presents an overview of existing software tools that are readily available for calculating some of the reviewed measures. Finally, discussions on challenges and future research are provided

    The link between ethnic segregation and socio-economic status : An activity space approach

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    The extent to which ethnic segregation results from differences in socio-economic factors remains a seminal topic of debate. The growing literature demonstrating the multifaceted phenomenon of segregation urges more focus on individuals' spatial and social interactions. We applied an activity space approach and considered ethnic differences in individuals' activity spaces as an indicator of spatial segregation. We used mobile phone and survey datasets in Estonia. We show that place-based segregation indices derived from both datasets indicate similar levels of ethnic segregation. From an activity space perspective, the results show that the main socio-economic factor affecting the extensity of activity spaces is self-estimated social status rather than education and income. Results show that ethnic inequality in spatial behaviour is not straightforward, but rather that it is linked to how individuals position themselves in society. We argue that socio-economic factors need to be controlled to examine ethnic segregation from activity space perspective.Peer reviewe

    Further studies on a hybrid cell-surface antigen associated with human chromosome 11 using a monoclonal antibody

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    A monoclonal antibody has been obtained that recognizes an antigen encoded by human chromosome 11. We present evidence that this monoclonal antibody recognizes the same or a similar antigenic activity as that previously called a 1 . Genetic information necessary for a 1 expression and recognition by the monoclonal antibody both map to 11p13 → 11pter. Mutants that have lost a 1 are no longer recognized by the monoclonal antibody. The macroglycolipid fraction of human erythrocyte membranes which contains the a 1 antigenic activity is able to convert antigen-negative Chinese hamster ovary cells into cells which are killed by the monoclonal antibody plus complement.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45556/1/11188_2005_Article_BF01543049.pd

    Observation of a new boson at a mass of 125 GeV with the CMS experiment at the LHC

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    Trends in distribution centres and their locations: sprawl and polarization

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    The logistics industry is an important sector for the Dutch economy. Distribution centres (DCs) are important to perform logistics activities. In 2015 the demand for logistics real estate has been particularly high compared to previous years. To facilitate the logistics sector and to develop sustainable spatial policies – that for example reduce congestion-it is important that spatial planners have insights in logistics location patterns. This paper analyses some trends in the spatial patterns of DC settlements within the Netherlands, based on real estate data. We find that the shares of logistics real estate of the provinces Limburg and Noord-Brabant marginally increased in the period 2004 – 2014, while the shares of all four Randstad provinces marginally decreased. This indicates that, although absolute growth has been high in the periphery (especially along the line Rotterdam – Noord-Brabant – Venlo), on a national level no significant sprawl of logistics real estate from the Randstad towards peripheral regions can be observed. On the regional level, polarization in the periphery is visible within regions that have been forming new logistics clusters. Another phenomenon which is relevant for spatial planners is the growing demand for very large DCs, in particular for e-commerce logistics activities. This implies that municipalities increasingly will have to supply large logistics land plots. Extra attention of spatial policy makers is also needed for re-use or transformation of existing distribution centres – of which the floor space is often considered too small-to prevent further increase of unsalable DCs. This study has not investigated possible explanations for the spatial patterns of logistics real estate within the Netherlands. We hope to follow up the present study with an explanatory analysis.Transport and LogisticsTransport and Plannin

    Options to Eliminate Animal-Derived Components of Cell Culture Media

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