The SAURON project – XVII. Stellar population analysis of the absorption line strength maps of 48 early-type galaxies

The definitive version can be found at: http://onlinelibrary.wiley.com/ Copyright Royal Astronomical SocietyWe present a stellar population analysis of the absorption line strength maps for 48 early-type galaxies from the SAURON sample. Using the line strength index maps of Hβ, Fe5015 and Mg b, measured in the Lick/IDS system and spatially binned to a constant signal-to-noise ratio, together with predictions from up-to-date stellar population models, we estimate the simple stellar population-equivalent (SSP-equivalent) age, metallicity and abundance ratio [α/Fe] over a two-dimensional field extending up to approximately one effective radius. A discussion of calibrations and differences between model predictions is given. Maps of SSP-equivalent age, metallicity and abundance ratio [α/Fe] are presented for each galaxy. We find a large range of SSP-equivalent ages in our sample, of which ∼40 per cent of the galaxies show signs of a contribution from a young stellar population. The most extreme cases of post-starburst galaxies, with SSP-equivalent ages of ≤3 Gyr observed over the full field-of-view, and sometimes even showing signs of residual star formation, are restricted to low-mass systems (σe≤ 100 km s−1 or ∼2 × 1010 M⊙). Spatially restricted cases of young stellar populations in circumnuclear regions can almost exclusively be linked to the presence of star formation in a thin, dusty disc/ring, also seen in the near-UV or mid-IR on top of an older underlying stellar population. The flattened components with disc-like kinematics previously identified in all fast rotators are shown to be connected to regions of distinct stellar populations. These range from the young, still star-forming circumnuclear discs and rings with increased metallicity preferentially found in intermediate-mass fast rotators, to apparently old structures with extended disc-like kinematics, which are observed to have an increased metallicity and mildly depressed [α/Fe] ratio compared to the main body of the galaxy. The slow rotators, often harbouring kinematically decoupled components (KDC) in their central regions, generally show no stellar population signatures over and above the well-known metallicity gradients in early-type galaxies and are largely consistent with old (≥10 Gyr) stellar populations. Using radially averaged stellar population gradients we find in agreement with Spolaor et al. a mass–metallicity gradient relation where low-mass fast rotators form a sequence of increasing metallicity gradient with increasing mass. For more massive systems (above ∼3.5 × 1010 M⊙) there is an overall downturn such that metallicity gradients become shallower with increased scatter at a given mass leading to the most massive systems being slow rotators with relatively shallow metallicity gradients. The observed shallower metallicity gradients and increased scatter could be a consequence of the competition between different star formation and assembly scenarios following a general trend of diminishing gas fractions and more equal-mass mergers with increasing mass, leading to the most massive systems being devoid of ordered motion and signs of recent star formation.Peer reviewe

The dynamics of a senescence plasmid in fungal populations

status: publishe

Testing Mass Determinations of Supermassive Black Holes via Stellar Kinematics

We investigate the accuracy of mass determinations M_BH of supermassive black holes in galaxies using dynamical models of the stellar kinematics. We compare 10 of our M_BH measurements, using integral-field OASIS kinematics, to published values. For a sample of 25 galaxies we confront our new M_BH derived using two modeling methods on the same OASIS data.Comment: 4 pages, 4 figures, LaTeX. To appear in "Hunting for the Dark: The Hidden Side of Galaxy Formation", Malta, 19-23 Oct. 2009, eds. V.P. Debattista and C.C. Popescu, AIP Conf. Ser., in pres

Calsequestrin as a risk factor in Graves’ hyperthyroidism and Graves’ ophthalmopathy patients

Background: The pathogenesis of Graves’ ophthalmopathy (GO), Graves’ hyperthyroidism (GH) and the mechanisms for its link to thyroid autoimmunity are poorly understood. Our research focuses on the role of the skeletal muscle calcium binding protein calsequestrin (CASQ1) in thyroid. We measured the concentration of the CASQ1 protein correlating levels with parameters of the eye signs, CASQ1 antibody levels and CASQ1 gene polymorphism rs3838284. Methods: CASQ1 protein was measured by quantitative Western Blotting. The protein concentrations were expressed as pmol/mg total protein by reference to CASQ1 standards. Results: Western blot analysis showed the presence of two forms of CASQ1 in the thyroid. The mean concentration of CASQ1 protein was significantly reduced in patients with Graves’ disease, compared to thyroid from control subjects with multi-nodular goitre or thyroid cancer. Although in patients with GO it was lower than that, compared with patients with GH this difference was not significant. Reduced CASQ1 in Graves’ thyroid correlated with the homozygous genotype of the rs3838284 CASQ1 polymorphism. Conclusions: Decreased CASQ1 in the thyroid of patients with Graves’ disease compared to thyroid from control subjects is not explained but may reflect consumption of the protein during an autoimmune reaction against CASQ1 in the thyroid

Association of Immunosuppression and Human Immunodeficiency Virus (HIV) Viremia with Anal Cancer Risk in Persons Living with HIV in the United States and Canada

Background: People living with human immunodeficiency virus (HIV; PLWH) have a markedly elevated anal cancer risk, largely due to loss of immunoregulatory control of oncogenic human papillomavirus infection. To better understand anal cancer development and prevention, we determined whether recent, past, cumulative, or nadir/peak CD4+ T-cell count (CD4) and/or HIV-1 RNA level (HIV RNA) best predict anal cancer risk. Methods: We studied 102 777 PLWH during 1996-2014 from 21 cohorts participating in the North American AIDS Cohort Collaboration on Research and Design. Using demographics-adjusted, cohort-stratified Cox models, we assessed associations between anal cancer risk and various time-updated CD4 and HIV RNA measures, including cumulative and nadir/peak measures during prespecified moving time windows. We compared models using the Akaike information criterion. Results: Cumulative and nadir/peak CD4 or HIV RNA measures from approximately 8.5 to 4.5 years in the past were generally better predictors for anal cancer risk than their corresponding more recent measures. However, the best model included CD4 nadir (ie, the lowest CD4) from approximately 8.5 years to 6 months in the past (hazard ratio [HR] for <50 vs ≥500 cells/μL, 13.4; 95% confidence interval [CI], 3.5-51.0) and proportion of time CD4 <200 cells/μL from approximately 8.5 to 4.5 years in the past (a cumulative measure; HR for 100% vs 0%, 3.1; 95% CI, 1.5-6.6). Conclusions: Our results are consistent with anal cancer promotion by severe, prolonged HIV-induced immunosuppression. Nadir and cumulative CD4 may represent useful markers for identifying PLWH at higher anal cancer risk

The SAURON project - XII. Kinematic substructures in early-type galaxies: evidence for disks in fast rotators

Original article can be found at: http://www3.interscience.wiley.com Copyright Royal Astronomical Society / Blackwell. DOI: 10.1111/j.1365-2966.2008.13712.xPeer reviewe