Analytical and numerical investigation of escape rate for a noise driven bath

We consider a system-reservoir model where the reservoir is modulated by an external noise. Both the internal noise of the reservoir and the external noise are stationary, Gaussian and are characterized by arbitrary decaying correlation functions. Based on a relation between the dissipation of the system and the response function of the reservoir driven by external noise we numerically examine the model using a full bistable potential to show that one can recover the turn-over features of the usual Kramers' dynamics when the external noise modulates the reservoir rather than the system directly. We derive the generalized Kramers' rate for this nonequilibrium open system. The theoretical results are verified by numerical simulation.Comment: Revtex, 25 pages, 5 figures. To appear in Phys. Rev.

Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture

The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated variants. We have quantified the variance in liability to disease explained

Carcass merit project: development of EPDS and genetic marker validation

Carcass and Warner-Bratzler shear force data on strip loin steaks have been obtained on over 4,200 cattle from contemporary progeny groups from the most widely used sires in 15 beef cattle breed associations (16 breeds). Trained sensory panel evaluations have been conducted on over 1,500 strip loin steaks from a sample of contemporary progeny groups from sires included in the QTL (quantitative trait loci) validation component of the project. One breed association has published Warner-Bratzler shear force Expected Progeny Differences (EPDs) for 57 sires of two breeds. DNA analyses and screening have been completed for 11 QTL on eight sires from several breeds. EPDs for carcass traits, Warner-Bratzler shear force, and sensory panel traits may be completed for several breeds within the year 2001. Information from this project should allow seedstock producers to improve carcass traits, tenderness, and other palatability traits through classical genetic selection or through DNA marker-assisted selection