545 research outputs found
Comments on Condensates in Non-Supersymmetric Orbifold Field Theories
Non-supersymmetric orbifolds of N=1 super Yang-Mills theories are conjectured
to inherit properties from their supersymmetric parent. We examine this
conjecture by compactifying the Z_2 orbifold theories on a spatial circle of
radius R. We point out that when the orbifold theory lies in the weakly coupled
vacuum of its parent, fractional instantons do give rise to the conjectured
condensate of bi-fundamental fermions. Unfortunately, we show that quantum
effects render this vacuum unstable through the generation of twisted
operators. In the true vacuum state, no fermion condensate forms. Thus, in
contrast to super Yang-Mills, the compactified orbifold theory undergoes a
chiral phase transition as R is varied.Comment: 10 Pages. Added clarifying comments, computational steps and a nice
pretty pictur
Mixed mode data clustering: an approach based on tectrachoric correlations
In this paper we face the problem of clustering mixedmode data by assuming that the observed binary variables aregenerated from latent continuous variables. We perform a principalcomponents analysis on the matrix of tetrachoric correlations and wethen estimate the scores of each latent variable and construct adata matrix with continuous variables to be used in fully Guassianmixture models or in the k-means cluster analysis. The calculationof the expected a posteriori (EAP) estimates may proceed by simplyconsidering a limited number of quadrature points. Results on asimulation study and on a real data set are reported
Natural Theories of Ultra-Low Mass PNGB's: Axions and Quintessence
We consider the Wilson Line PNGB which arises in a U(1)^N gauge theory,
abstracted from a latticized, periodically compactified extra dimension U(1).
Planck scale breaking of the PNGB's global symmetry is suppressed, providing
natural candidates for the axion and quintessence. We construct an explicit
model in which the axion may be viewed as the 5th component of the U(1)_Y gauge
field in a 1+4 latticized periodically compactified extra dimension. We also
construct a quintessence PNGB model where the ultra-low mass arises from
Planck-scale suppressed physics itself.Comment: 20 pages, fixed typo and reference
Ultrafast quasiparticle relaxation dynamics in normal metals and heavy fermion materials
We present a detailed theoretical study of the ultrafast quasiparticle
relaxation dynamics observed in normal metals and heavy fermion materials with
femtosecond time-resolved optical pump-probe spectroscopy. For normal metals, a
nonthermal electron distribution gives rise to a temperature (T) independent
electron-phonon relaxation time at low temperatures, in contrast to the
T^{-3}-divergent behavior predicted by the two-temperature model. For heavy
fermion compounds, we find that the blocking of electron-phonon scattering for
heavy electrons within the density-of-states peak near the Fermi energy is
crucial to explain the rapid increase of the electron-phonon relaxation time
below the Kondo temperature. We propose the hypothesis that the slower Fermi
velocity compared to the sound velocity provides a natural blocking mechanism
due to energy and momentum conservation laws.Comment: 10 pages, 11 figure
Recommended from our members
Numerical simulation of the SLAC X-100 klystron using RKTW2D
We have performed numerical simulations of the X-100 klystron being developed at Stanford Linear Accelerator Center. The X-100 is being developed as a possible source for the next generation of linear collider, and will be required to produce {approx}100 MW of power for a duration of {approx}800 ns. Our simulations were performed using the simulation programs RKTW1D and RKTW2D, developed at Lawrence Livermore National Laboratory. The codes were used to investigate the operation of the klystron over a wide range of operating conditions. We will present comparisons of the simulation results with experimental results. 3 refs., 5 figs
Clinical activity of ipilimumab for metastatic uveal melanoma: a retrospective review of the Dana-Farber Cancer Institute, Massachusetts General Hospital, Memorial Sloan-Kettering Cancer Center, and University Hospital of Lausanne experience.
BACKGROUND: Uveal melanoma exhibits a high incidence of metastases; and, to date, there is no systemic therapy that clearly improves outcomes. The anticytotoxic T-lymphocyte-associated protein 4 (anti-CTLA-4) antibody ipilimumab is a standard of care for metastatic melanoma; however, the clinical activity of CTLA-4 inhibition in patients with metastatic uveal melanoma is poorly defined.
METHODS: To assess ipilimumab in this setting, the authors performed a multicenter, retrospective analysis of 4 hospitals in the United States and Europe. Clinical characteristics, toxicities, and radiographic disease burden, as determined by central, blinded radiology review, were evaluated.
RESULTS: Thirty-nine patients with uveal melanoma were identified, including 34 patients who received 3 mg/kg ipilimumab and 5 who received 10 mg/kg ipilimumab. Immune-related response criteria and modified World Health Organization criteria were used to assess the response rate (RR) and the combined response plus stable disease (SD) rate after 12 weeks, after 23 weeks, and overall (median follow-up, 50.4 weeks [12.6 months]). At week 12, the RR was 2.6%, and the response plus SD rate was 46.%; at week 23, the RR was 2.6%, and the response plus SD rate was 28.2%. There was 1 complete response and 1 late partial response (at 100 weeks after initial SD) for an immune-related RR of 5.1%. Immune-related adverse events were observed in 28 patients (71.8%) and included 7 (17.9%) grade 3 and 4 events. Immune-related adverse events were more frequent in patients who received 10 mg/kg ipilimumab than in those who received 3 mg/kg ipilimumab. The median overall survival from the first dose of ipilimumab was 9.6 months (95% confidence interval, 6.3-13.4 months; range, 1.6-41.6 months). Performance status, lactate dehydrogenase level, and an absolute lymphocyte count ≥ 1000 cells/μL at week 7 were associated significantly with survival.
CONCLUSIONS: In this multicenter, retrospective analysis of 4 hospitals in the United States and Europe of patients with uveal melanoma, durable responses to ipilimumab and manageable toxicity were observed
A Complete Theory of Grand Unification in Five Dimensions
A fully realistic unified theory is constructed, with SU(5) gauge symmetry
and supersymmetry both broken by boundary conditions in a fifth dimension.
Despite the local explicit breaking of SU(5) at a boundary of the dimension,
the large size of the extra dimension allows precise predictions for gauge
coupling unification, alpha_s(M_Z) = 0.118 \pm 0.003, and for Yukawa coupling
unification, m_b(M_Z) = 3.3 \pm 0.2 GeV. A complete understanding of the MSSM
Higgs sector is given; with explanations for why the Higgs triplets are heavy,
why the Higgs doublets are protected from a large tree-level mass, and why the
mu and B parameters are naturally generated to be of order the SUSY breaking
scale. All sources of d=4,5 proton decay are forbidden, while a new origin for
d=6 proton decay is found to be important. Several aspects of flavor follow
from an essentially unique choice of matter location in the fifth dimension:
only the third generation has an SU(5) mass relation, and the lighter two
generations have small mixings with the heaviest generation. The entire
superpartner spectrum is predicted in terms of only two free parameters. The
squark and slepton masses are determined by their location in the fifth
dimension, allowing a significant experimental test of the detailed structure
of the extra dimension. Lepton flavor violation is found to be generically
large in higher dimensional unified theories with high mediation scales of SUSY
breaking. In our theory this forces a common location for all three neutrinos,
predicting large neutrino mixing angles. Rates for mu -> e gamma, mu -> e e e,
mu -> e conversion and tau -> mu gamma are larger in our theory than in
conventional 4D supersymmetric GUTs. Proposed experiments probing mu -> e
transitions will probe the entire interesting parameter space of our theory.Comment: 51 pages, late
Observing Supermassive Black Holes across cosmic time: from phenomenology to physics
In the last decade, a combination of high sensitivity, high spatial
resolution observations and of coordinated multi-wavelength surveys has
revolutionized our view of extra-galactic black hole (BH) astrophysics. We now
know that supermassive black holes reside in the nuclei of almost every galaxy,
grow over cosmological times by accreting matter, interact and merge with each
other, and in the process liberate enormous amounts of energy that influence
dramatically the evolution of the surrounding gas and stars, providing a
powerful self-regulatory mechanism for galaxy formation. The different
energetic phenomena associated to growing black holes and Active Galactic
Nuclei (AGN), their cosmological evolution and the observational techniques
used to unveil them, are the subject of this chapter. In particular, I will
focus my attention on the connection between the theory of high-energy
astrophysical processes giving rise to the observed emission in AGN, the
observable imprints they leave at different wavelengths, and the methods used
to uncover them in a statistically robust way. I will show how such a combined
effort of theorists and observers have led us to unveil most of the SMBH growth
over a large fraction of the age of the Universe, but that nagging
uncertainties remain, preventing us from fully understating the exact role of
black holes in the complex process of galaxy and large-scale structure
formation, assembly and evolution.Comment: 46 pages, 21 figures. This review article appears as a chapter in the
book: "Astrophysical Black Holes", Haardt, F., Gorini, V., Moschella, U and
Treves A. (Eds), 2015, Springer International Publishing AG, Cha
Signal Recovery and System Calibration from Multiple Compressive Poisson Measurements
The measurement matrix employed in compressive sensing typically cannot be known precisely a priori, and must be estimated via calibration. One may take multiple compressive measurements, from which the measurement matrix and underlying signals may be estimated jointly. This is of interest as well when the measurement matrix may change as a function of the details of what is measured. This problem has been considered recently for Gaussian measurement noise, and here we develop this idea with application to Poisson systems. An optimization-based algorithm is proposed, and associated theoretical performance guarantees are established based on newly derived concentration-of-measure results. A Bayesian model is then introduced, to improve exibility and generality. Connections between the optimization-based methods and the Bayesian model are developed, and example results are presented for a real compressive x-ray imaging system
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